Competition between translation initiation factor eIF5 and its mimic protein 5MP determines non-AUG initiation rate genome-wide

Translation from unconventional 5′ start sites drives tumour initiation

(2017) Ataman Sendoel et al.   NATURE

Molecular Landscape of the Ribosome Pre-initiation Complex during mRNA Scanning: Structural Role for eIF3c and Its Control by eIF5

(2017) Eiji Obayashi et al.   Cell Reports

Cap-independent translation by DAP5 controls cell fate decisions in human embryonic stem cells

(2016) Yael Yoffe et al.   GENES & DEVELOPMENT

Upstream Open Reading Frames Differentially Regulate Gene-specific Translation in the Integrated Stress Response

(2016) Sara K. Young et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Overexpression of eIF5 or its protein mimic 5MP perturbs eIF2 function and inducesATF4translation through delayed re-initiation

(2016) Caitlin Kozel et al.   NUCLEIC ACIDS RESEARCH

Nat1promotes translation of specific proteins that induce differentiation of mouse embryonic stem cells

(2016) Hayami Sugiyama et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Translational control by 5'-untranslated regions of eukaryotic mRNAs

(2016) A. G. Hinnebusch et al.   SCIENCE

Systematic analysis of thePTEN5′ leader identifies a major AUU initiated proteoform

(2016) Ioanna Tzani et al.   Open Biology

Regulation of osteoblast development by Bcl-2-associated athanogene-1 (BAG-1)

(2016) Joanna Greenhough et al.   Scientific Reports

ABC50 mutants modify translation start codon selection

(2015) Joanna D. Stewart et al.   BIOCHEMICAL JOURNAL

Translational Tolerance of Mitochondrial Genes to Metabolic Energy Stress Involves TISU and eIF1-eIF4GI Cooperation in Start Codon Selection

(2015) Hadar Sinvani et al.   Cell Metabolism

The Scanning Mechanism of Eukaryotic Translation Initiation

(2014) Alan G. Hinnebusch   Annual Review of Biochemistry

Pioneer transcription factors in cell reprogramming

(2014) Makiko Iwafuchi-Doi et al.   GENES & DEVELOPMENT

Essential role of eIF5-mimic protein in animal development is linked to control of ATF4 expression

(2014) Hiroyuki Hiraishi et al.   NUCLEIC ACIDS RESEARCH

The Interaction between Eukaryotic Initiation Factor 1A and eIF5 Retains eIF1 within Scanning Preinitiation Complexes

(2013) Rafael E. Luna et al.   BIOCHEMISTRY

Coordinated Movements of Eukaryotic Translation Initiation Factors eIF1, eIF1A, and eIF5 Trigger Phosphate Release from eIF2 in Response to Start Codon Recognition by the Ribosomal Preinitiation Complex

(2013) Jagpreet S. Nanda et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

β-Hairpin Loop of Eukaryotic Initiation Factor 1 (eIF1) Mediates 40 S Ribosome Binding to Regulate Initiator tRNAMetRecruitment and Accuracy of AUG Selectionin Vivo

(2013) Pilar Martin-Marcos et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Global mapping of translation initiation sites in mammalian cells at single-nucleotide resolution

(2012) S. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Leucine-tRNA Initiates at CUG Start Codons for Protein Synthesis and Presentation by MHC Class I

(2012) S. R. Starck et al.   SCIENCE

The C-Terminal Domain of Eukaryotic Initiation Factor 5 Promotes Start Codon Recognition by Its Dynamic Interplay with eIF1 and eIF2β

(2012) Rafael E. Luna et al.   Cell Reports

Ribosome Profiling of Mouse Embryonic Stem Cells Reveals the Complexity and Dynamics of Mammalian Proteomes

(2011) Nicholas T. Ingolia et al.   CELL

Efficient expression and purification of human replication fork-stabilizing factor, Claspin, from mammalian cells: DNA-binding activity and novel protein interactions

(2011) Syuzi Uno et al.   GENES TO CELLS

Functional Elements in Initiation Factors 1, 1A, and 2  Discriminate against Poor AUG Context and Non-AUG Start Codons

(2011) P. Martin-Marcos et al.   MOLECULAR AND CELLULAR BIOLOGY

Mechanisms of translational regulation by a human eIF5-mimic protein

(2011) Chingakham Ranjit Singh et al.   NUCLEIC ACIDS RESEARCH

Identification of evolutionarily conserved non-AUG-initiated N-terminal extensions in human coding sequences

(2011) Ivaylo P. Ivanov et al.   NUCLEIC ACIDS RESEARCH

Upstream open reading frames: Molecular switches in (patho)physiology

(2010) Klaus Wethmar et al.   BIOESSAYS

The GCN2-ATF4 pathway is critical for tumour cell survival and proliferation in response to nutrient deprivation

(2010) Jiangbin Ye et al.   EMBO JOURNAL

Initiation context modulates autoregulation of eukaryotic translation initiation factor 1 (eIF1)

(2010) I. P. Ivanov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

BZW1, a novel proliferation regulator that promotes growth of salivary muocepodermoid carcinoma

(2009) Shaoqing Li et al.   CANCER LETTERS

eIF1 Controls Multiple Steps in Start Codon Recognition during Eukaryotic Translation Initiation

(2009) Jagpreet S. Nanda et al.   JOURNAL OF MOLECULAR BIOLOGY

DAP5 Promotes Cap-Independent Translation of Bcl-2 and CDK1 to Facilitate Cell Survival during Mitosis

(2008) Lea Marash et al.   MOLECULAR CELL

Rapid evolution of protein kinase PKR alters sensitivity to viral inhibitors

(2008) Stefan Rothenburg et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY