To protect and modify double-stranded RNA – the critical roles of ADARs in development, immunity and oncogenesis

Membrane and synaptic defects leading to neurodegeneration in Adar mutant Drosophila are rescued by increased autophagy

(2020) Anzer Khan et al.   BMC BIOLOGY

An internal deletion of ADAR rescued by MAVS deficiency leads to a minute phenotype

(2020) Prajakta Bajad et al.   NUCLEIC ACIDS RESEARCH

Deletion of Endonuclease V suppresses chemically induced hepatocellular carcinoma

(2020) Xiang Yi Kong et al.   NUCLEIC ACIDS RESEARCH

Caenorhabditis elegans ADAR editing and the ERI-6/7/MOV10 RNAi pathway silence endogenous viral elements and LTR retrotransposons

(2020) Sylvia E. J. Fischer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ADAR1 mediated regulation of neural crest derived melanocytes and Schwann cell development

(2020) Nadjet Gacem et al.   Nature Communications

Cis- and trans-regulations of pre-mRNA splicing by RNA editing enzymes influence cancer development

(2020) Sze Jing Tang et al.   Nature Communications

Novel Engineered Programmable Systems for ADAR-Mediated RNA Editing

(2020) Guillermo Aquino-Jarquin   Molecular Therapy-Nucleic Acids

irCLASH reveals RNA substrates recognized by human ADARs

(2020) Yulong Song et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

ADAR1-mediated RNA editing is a novel oncogenic process in thyroid cancer and regulates miR-200 activity

(2020) Julia Ramírez-Moya et al.   ONCOGENE

Adar RNA editing-dependent and -independent effects are required for brain and innate immune functions in Drosophila

(2020) Patricia Deng et al.   Nature Communications

ADAR-deficiency perturbs the global splicing landscape in mouse tissues

(2020) Utkarsh Kapoor et al.   GENOME RESEARCH

In Vivo Repair of a Protein Underlying a Neurological Disorder by Programmable RNA Editing

(2020) John R. Sinnamon et al.   Cell Reports

Suppression of adenosine-to-inosine (A-to-I) RNA editome by death associated protein 3 (DAP3) promotes cancer progression

(2020) Jian Han et al.   Science Advances

MicroRNAs: From Mechanism to Organism

(2020) Philipp J. Dexheimer et al.   Frontiers in Cell and Developmental Biology

In vivo RNA editing of point mutations via RNA-guided adenosine deaminases

(2019) Dhruva Katrekar et al.   NATURE METHODS

Precise RNA editing by recruiting endogenous ADARs with antisense oligonucleotides

(2019) Tobias Merkle et al.   NATURE BIOTECHNOLOGY

Double-Stranded RNA Sensors and Modulators in Innate Immunity

(2019) Sun Hur   Annual Review of Immunology

Disruption in A-to-I Editing Levels Affects C. elegans Development More Than a Complete Lack of Editing

(2019) Nabeel S. Ganem et al.   Cell Reports

Cancer the‘RBP’eutics–RNA-binding proteins as therapeutic targets for cancer

(2019) Shakur Mohibi et al.   PHARMACOLOGY & THERAPEUTICS

ADAR1: “Editor-in-Chief” of Cytoplasmic Innate Immunity

(2019) Mart M. Lamers et al.   Frontiers in Immunology

A high resolution A-to-I editing map in the mouse identifies editing events controlled by pre-mRNA splicing

(2019) Konstantin Licht et al.   GENOME RESEARCH

Tumor neoantigens: from basic research to clinical applications

(2019) Tao Jiang et al.   Journal of Hematology & Oncology

RNA binding candidates for human ADAR3 from substrates of a gain of function mutant expressed in neuronal cells

(2019) Yuru Wang et al.   NUCLEIC ACIDS RESEARCH

A-to-I–edited miRNA-379-5p inhibits cancer cell proliferation through CD97-induced apoptosis

(2019) Xiaoyan Xu et al.   JOURNAL OF CLINICAL INVESTIGATION

Cardiac valve involvement in ADAR-related type I interferonopathy

(2019) Yanick Crow et al.   JOURNAL OF MEDICAL GENETICS

Stress granules and neurodegeneration

(2019) Benjamin Wolozin et al.   NATURE REVIEWS NEUROSCIENCE

The Editor’s I on Disease Development

(2019) Mamta Jain et al.   TRENDS IN GENETICS

Selective Recognition of RNA Substrates by ADAR Deaminase Domains

(2018) Yuru Wang et al.   BIOCHEMISTRY

A-to-I RNA Editing Contributes to Proteomic Diversity in Cancer

(2018) Xinxin Peng et al.   CANCER CELL

CircNT5E acts as a sponge of microRNA-422a to promote glioblastoma tumorigenesis

(2018) Renjie Wang et al.   CANCER RESEARCH

Human ADAR1 Prevents Endogenous RNA from Triggering Translational Shutdown

(2018) Hachung Chung et al.   CELL

Breaching Self-Tolerance to Alu Duplex RNA Underlies MDA5-Mediated Inflammation

(2018) Sadeem Ahmad et al.   CELL

All I's on the RADAR: role of ADAR in gene regulation

(2018) Galina Shevchenko et al.   FEBS LETTERS

C. elegansADARs antagonize silencing of cellular dsRNAs by the antiviral RNAi pathway

(2018) Daniel P. Reich et al.   GENES & DEVELOPMENT

Eight Novel Mutations of the ADAR1 Gene in Chinese Patients with Dyschromatosis Symmetrica Hereditaria

(2018) Zhuang-li Tang et al.   Genetic Testing and Molecular Biomarkers

RNA editing in nascent RNA affects pre-mRNA splicing

(2018) Yun-Hua Esther Hsiao et al.   GENOME RESEARCH

Decreased A-to-I RNA editing as a source of keratinocytes' dsRNA in psoriasis

(2018) Lea Shallev et al.   RNA

ADARs and editing: The role of A-to-I RNA modification in cancer progression

(2018) Kajsa Fritzell et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

A-to-I miR-378a-3p editing can prevent melanoma progression via regulation of PARVA expression

(2018) Guermarie Velazquez-Torres et al.   Nature Communications

Increased RNA Editing May Provide a Source for Autoantigens in Systemic Lupus Erythematosus

(2018) Shalom Hillel Roth et al.   Cell Reports

Adar3 Is Involved in Learning and Memory in Mice

(2018) Dessislava Mladenova et al.   Frontiers in Neuroscience

Aberrant hyperediting of the myeloma transcriptome by ADAR1 confers oncogenicity and is a marker of poor prognosis

(2018) Phaik Ju Teoh et al.   BLOOD

A protein–protein interaction underlies the molecular basis for substrate recognition by an adenosine-to-inosine RNA-editing enzyme

(2018) Suba Rajendren et al.   NUCLEIC ACIDS RESEARCH

RNA editing derived epitopes function as cancer antigens to elicit immune responses

(2018) Minying Zhang et al.   Nature Communications

ADAR3 expression is an independent prognostic factor in lower-grade diffuse gliomas and positively correlated with the editing level of GRIA2Q607R

(2018) Ying Zhang et al.   Cancer Cell International

Current strategies for Site-Directed RNA Editing using ADARs

(2018) Maria Fernanda Montiel-Gonzalez et al.   METHODS

Loss of ADAR1 in tumours overcomes resistance to immune checkpoint blockade

(2018) Jeffrey J. Ishizuka et al.   NATURE

Tumor-derived IFN triggers chronic pathway agonism and sensitivity to ADAR loss

(2018) Huayang Liu et al.   NATURE MEDICINE

Inosine induces context-dependent recoding and translational stalling

(2018) Konstantin Licht et al.   NUCLEIC ACIDS RESEARCH

Identification of ADAR1 adenosine deaminase dependency in a subset of cancer cells

(2018) Hugh S. Gannon et al.   Nature Communications

Systematic characterization of A-to-I RNA editing hotspots in microRNAs across human cancers

(2017) Yumeng Wang et al.   GENOME RESEARCH

Adenosine Deaminase That Acts on RNA 3 (ADAR3) Binding to Glutamate Receptor Subunit B Pre-mRNA Inhibits RNA Editing in Glioblastoma

(2017) Eimile Oakes et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A-to-I RNA Editing Up-regulates Human Dihydrofolate Reductase in Breast Cancer

(2017) Masataka Nakano et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A-to-I RNA Editing in the Earliest-Diverging Eumetazoan Phyla

(2017) Hagit T. Porath et al.   MOLECULAR BIOLOGY AND EVOLUTION

ADAR2/miR-589-3p axis controls glioblastoma cell migration/invasion

(2017) Valeriana Cesarini et al.   NUCLEIC ACIDS RESEARCH

Human cancer tissues exhibit reduced A-to-I editing of miRNAs coupled with elevated editing of their targets

(2017) Yishay Pinto et al.   NUCLEIC ACIDS RESEARCH

RNA editing ofSLC22A3drives early tumor invasion and metastasis in familial esophageal cancer

(2017) Li Fu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Site-directed RNA repair of endogenous Mecp2 RNA in neurons

(2017) John R. Sinnamon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Abundant off-target edits from site-directed RNA editing can be reduced by nuclear localization of the editing enzyme

(2017) Isabel C. Vallecillo-Viejo et al.   RNA Biology

ALU ternative Regulation for Gene Expression

(2017) Ling-Ling Chen et al.   TRENDS IN CELL BIOLOGY

Pathogenesis of Human Systemic Lupus Erythematosus: A Cellular Perspective

(2017) Vaishali R. Moulton et al.   TRENDS IN MOLECULAR MEDICINE

ADAR1 expression is associated with tumour-infiltrating lymphocytes in triple-negative breast cancer

(2017) In Hye Song et al.   TUMOR BIOLOGY

RNA editing of AZIN1 induces the malignant progression of non-small-cell lung cancers

(2017) Xueda Hu et al.   TUMOR BIOLOGY

ADAR1-mediated 3′ UTR editing and expression control of antiapoptosis genes fine-tunes cellular apoptosis response

(2017) Chang-Ching Yang et al.   Cell Death & Disease

Alu-dependent RNA editing of GLI1 promotes malignant regeneration in multiple myeloma

(2017) Elisa Lazzari et al.   Nature Communications

The C. elegans neural editome reveals an ADAR target mRNA required for proper chemotaxis

(2017) Sarah N Deffit et al.   eLife

Differential Binding of Three Major Human ADAR Isoforms to Coding and Long Non-Coding Transcripts

(2017) Josephine Galipon et al.   Genes

ADAR-Mediated RNA Editing Predicts Progression and Prognosis of Gastric Cancer

(2016) Tim Hon Man Chan et al.   GASTROENTEROLOGY

ADAR2 functions as a tumor suppressor via editing IGFBP7 in esophageal squamous cell carcinoma

(2016) Yuan-Bin Chen et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Structures of human ADAR2 bound to dsRNA reveal base-flipping mechanism and basis for site selectivity

(2016) Melissa M Matthews et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Neurologic Phenotypes Associated with Mutations in TREX1, RNASEH2A, RNASEH2B, RNASEH2C, SAMHD1, ADAR1, and IFIH1: Aicardi–Goutières Syndrome and Beyond

(2016) Yanick Crow et al.   NEUROPEDIATRICS

Transandcisfactors affecting A-to-I RNA editing efficiency of a noncoding editing target inC. elegans

(2016) Michael C. Washburn et al.   RNA

The mRNA-edited form of GABRA3 suppresses GABRA3-mediated Akt activation and breast cancer metastasis

(2016) Kiranmai Gumireddy et al.   Nature Communications

Structures of human ADAR2 bound to dsRNA reveal base-flipping mechanism and basis for site selectivity

(2016) Melissa M Matthews et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The origin of the ADAR gene family and animal RNA editing

(2015) Laura F Grice et al.   BMC EVOLUTIONARY BIOLOGY

The Genomic Landscape and Clinical Relevance of A-to-I RNA Editing in Human Cancers

(2015) Leng Han et al.   CANCER CELL

RNA over-editing of BLCAP contributes to hepatocarcinogenesis identified by whole-genome and transcriptome sequencing

(2015) Xueda Hu et al.   CANCER LETTERS

The dynamic epitranscriptome: A to I editing modulates genetic information

(2015) Mansoureh Tajaddod et al.   CHROMOSOMA

Isoforms of RNA-Editing Enzyme ADAR1 Independently Control Nucleic Acid Sensor MDA5-Driven Autoimmunity and Multi-organ Development

(2015) Kathleen Pestal et al.   IMMUNITY

The emerging role of RNA editing in plasticity

(2015) J. J. C. Rosenthal   JOURNAL OF EXPERIMENTAL BIOLOGY

hiCLIP reveals the in vivo atlas of mRNA secondary structures recognized by Staufen 1

(2015) Yoichiro Sugimoto et al.   NATURE

The octopus genome and the evolution of cephalopod neural and morphological novelties

(2015) Caroline B. Albertin et al.   NATURE

Reduced adenosine-to-inosine miR-455-5p editing promotes melanoma growth and metastasis

(2015) Einav Shoshan et al.   NATURE CELL BIOLOGY

Noncoding regions ofC. elegansmRNA undergo selective adenosine to inosine deamination and contain a small number of editing sites per transcript

(2015) Emily C Wheeler et al.   RNA Biology

The Ro60 autoantigen binds endogenous retroelements and regulates inflammatory gene expression

(2015) T. Hung et al.   SCIENCE

RNA editing by ADAR1 prevents MDA5 sensing of endogenous dsRNA as nonself

(2015) B. J. Liddicoat et al.   SCIENCE

Genomic analysis of ADAR1 binding and its involvement in multiple RNA processing pathways

(2015) Jae Hoon Bahn et al.   Nature Communications

Profiling RNA editing in human tissues: towards the inosinome Atlas

(2015) Ernesto Picardi et al.   Scientific Reports

Elevated RNA Editing Activity Is a Major Contributor to Transcriptomic Diversity in Tumors

(2015) Nurit Paz-Yaacov et al.   Cell Reports

ADAR1, inosine and the immune sensing system: distinguishing self from non-self

(2015) Brian J. Liddicoat et al.   Wiley Interdisciplinary Reviews-RNA

To edit or not to edit: regulation of ADAR editing specificity and efficiency

(2015) Sarah N. Deffit et al.   Wiley Interdisciplinary Reviews-RNA

The majority of transcripts in the squid nervous system are extensively recoded by A-to-I RNA editing

(2015) Shahar Alon et al.   eLife

Modulation of microRNA editing, expression and processing by ADAR2 deaminase in glioblastoma

(2015) Sara Tomaselli et al.   GENOME BIOLOGY

RNA interference-mediated antiviral defense in insects

(2015) Don B Gammon et al.   Current Opinion in Insect Science

Positive correlation between ADAR expression and its targets suggests a complex regulation mediated by RNA editing in the human brain

(2015) Noa Liscovitch et al.   RNA Biology

Five novel mutations in the ADAR1 gene associated with dyschromatosis symmetrica hereditaria

(2014) Qi Liu et al.   BMC Medical Genetics

RNA editing inRHOQpromotes invasion potential in colorectal cancer

(2014) Sae-Won Han et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Adenosine Deaminase Acting on RNA 1 Limits RIG-I RNA Detection and Suppresses IFN Production Responding to Viral and Endogenous RNAs

(2014) Shengyong Yang et al.   JOURNAL OF IMMUNOLOGY

Gain-of-function mutations in IFIH1 cause a spectrum of human disease phenotypes associated with upregulated type I interferon signaling

(2014) Gillian I Rice et al.   NATURE GENETICS

Mapping the miRNA interactome by cross-linking ligation and sequencing of hybrids (CLASH)

(2014) Aleksandra Helwak et al.   Nature Protocols

Optimal guideRNAs for re-directing deaminase activity of hADAR1 and hADAR2 in trans

(2014) Marius F. Schneider et al.   NUCLEIC ACIDS RESEARCH

Deciphering key features in protein structures with the new ENDscript server

(2014) Xavier Robert et al.   NUCLEIC ACIDS RESEARCH

A bimodular nuclear localization signal assembled via an extended double-stranded RNA-binding domain acts as an RNA-sensing signal for transportin 1

(2014) P. Barraud et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

‘Black sheep’ that don’t leave the double-stranded RNA-binding domain fold

(2014) Michael L. Gleghorn et al.   TRENDS IN BIOCHEMICAL SCIENCES

The RNA-Editing Enzyme ADAR1 Controls Innate Immune Responses to RNA

(2014) Niamh M. Mannion et al.   Cell Reports

The dsRBP and Inactive Editor ADR-1 Utilizes dsRNA Binding to Regulate A-to-I RNA Editing across the C. elegans Transcriptome

(2014) Michael C. Washburn et al.   Cell Reports

Psoriasis

(2014) P. Di Meglio et al.   Cold Spring Harbor Perspectives in Medicine

Potent and Selective Inhibition of A-to-I RNA Editing with 2′-O-Methyl/Locked Nucleic Acid-Containing Antisense Oligoribonucleotides

(2013) Rena A. Mizrahi et al.   ACS Chemical Biology

Adenosine-to-Inosine RNA Editing Mediated by ADARs in Esophageal Squamous Cell Carcinoma

(2013) Y.-R. Qin et al.   CANCER RESEARCH

ADAR1 Forms a Complex with Dicer to Promote MicroRNA Processing and RNA-Induced Gene Silencing

(2013) Hiromitsu Ota et al.   CELL

STAU1 binding 3' UTR IRAlus complements nuclear retention to protect cells from PKR-mediated translational shutdown

(2013) R. A. Elbarbary et al.   GENES & DEVELOPMENT

A disrupted RNA editing balance mediated by ADARs (Adenosine DeAminases that act on RNA) in human hepatocellular carcinoma

(2013) Tim Hon Man Chan et al.   GUT

NovelADAR1mutations including a single amino acid deletion in the deaminase domain underlie dyschromatosis symmetrica hereditaria in Japanese families

(2013) Michihiro Kono et al.   INTERNATIONAL JOURNAL OF DERMATOLOGY

A type I interferon signature identifies bilateral striatal necrosis due to mutations inADAR1

(2013) John H Livingston et al.   JOURNAL OF MEDICAL GENETICS

Recoding RNA editing of AZIN1 predisposes to hepatocellular carcinoma

(2013) Leilei Chen et al.   NATURE MEDICINE

Genome-wide analysis of A-to-I RNA editing by single-molecule sequencing in Drosophila

(2013) Georges St Laurent et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

ADAR2-Mediated Editing of miR-214 and miR-122 Precursor and Antisense RNA Transcripts in Liver Cancers

(2013) Wan-Hsin Liu et al.   PLoS One

Correction of mutations within the cystic fibrosis transmembrane conductance regulator by site-directed RNA editing

(2013) M. F. Montiel-Gonzalez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RNA editing of the GLI1 transcription factor modulates the output of Hedgehog signaling

(2013) Takashi Shimokawa et al.   RNA Biology

ADAR1 regulates ARHGAP26 gene expression through RNA editing by disrupting miR-30b-3p and miR-573 binding

(2013) Q. Wang et al.   RNA

Global regulation of alternative splicing by adenosine deaminase acting on RNA (ADAR)

(2013) O. Solomon et al.   RNA

Endonuclease V cleaves at inosines in RNA

(2013) Erik Sebastian Vik et al.   Nature Communications

Adenosine-to-inosine RNA editing and human disease

(2013) William Slotkin et al.   Genome Medicine

An RNA-Deaminase Conjugate Selectively Repairs Point Mutations

(2012) Thorsten Stafforst et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Down-regulation of miR-214 contributes to intrahepatic cholangiocarcinoma metastasis by targeting Twist

(2012) Bin Li et al.   FEBS Journal

A novel mutation of the DSRAD gene in a Chinese family with dyschromatosis symmetrica hereditaria

(2012) M.L. Lai et al.   GENETICS AND MOLECULAR RESEARCH

A-to-I editing of microRNAs in the mammalian brain increases during development

(2012) Y. Ekdahl et al.   GENOME RESEARCH

Effects of ADARs on small RNA processing pathways in C. elegans

(2012) M. B. Warf et al.   GENOME RESEARCH

Extra Double-stranded RNA Binding Domain (dsRBD) in a Squid RNA Editing Enzyme Confers Resistance to High Salt Environment

(2012) Juan Pablo Palavicini et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Attenuated adenosine-to-inosine editing of microRNA-376a* promotes invasiveness of glioblastoma cells

(2012) Yukti Choudhury et al.   JOURNAL OF CLINICAL INVESTIGATION

Dyschromatosis symmetrica hereditaria

(2012) Masahiro Hayashi et al.   JOURNAL OF DERMATOLOGY

Mutations in ADAR1 cause Aicardi-Goutières syndrome associated with a type I interferon signature

(2012) Gillian I Rice et al.   NATURE GENETICS

Inverted Alu dsRNA structures do not affect localization but can alter translation efficiency of human mRNAs independent of RNA editing

(2012) Claire R. Capshew et al.   NUCLEIC ACIDS RESEARCH

Steric antisense inhibition of AMPA receptor Q/R editing reveals tight coupling to intronic editing sites and splicing

(2012) Andrew C. Penn et al.   NUCLEIC ACIDS RESEARCH

ADAR2-editing activity inhibits glioblastoma growth through the modulation of the CDC14B/Skp2/p21/p27 axis

(2012) F Galeano et al.   ONCOGENE

Mechanistic insights into editing-site specificity of ADARs

(2012) A. Kuttan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The ADAR protein family

(2012) Yiannis A Savva et al.   GENOME BIOLOGY

3'-UTR-located inverted Alu repeats facilitate mRNA translational repression and stress granule accumulation

(2012) Terry Fitzpatrick et al.   Nucleus

Immune Signaling by RIG-I-like Receptors

(2011) Yueh-Ming Loo et al.   IMMUNITY

Functional conservation in human and Drosophila of Metazoan ADAR2 involved in RNA editing: loss of ADAR1 in insects

(2011) Liam P. Keegan et al.   NUCLEIC ACIDS RESEARCH

Site-selective versus promiscuous A-to-I editing

(2011) Helene Wahlstedt et al.   Wiley Interdisciplinary Reviews-RNA

Functions and Regulation of RNA Editing by ADAR Deaminases

(2010) Kazuko Nishikura   Annual Review of Biochemistry

Consistent levels of A-to-I RNA editing across individuals in coding sequences and non-conserved Alu repeats

(2010) Shoshana Greenberger et al.   BMC GENOMICS

The Solution Structure of the ADAR2 dsRBM-RNA Complex Reveals a Sequence-Specific Readout of the Minor Groove

(2010) Richard Stefl et al.   CELL

The developmental transcriptome of Drosophila melanogaster

(2010) Brenton R. Graveley et al.   NATURE

Double-stranded RNAs containing multiple IU pairs are sufficient to suppress interferon induction and apoptosis

(2010) Patrice Vitali et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

RNA editing enzyme adenosine deaminase is a restriction factor for controlling measles virus replication that also is required for embryogenesis

(2010) S. V. Ward et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RNA-Regulated Interaction of Transportin-1 and Exportin-5 with the Double-Stranded RNA-Binding Domain Regulates Nucleocytoplasmic Shuttling of ADAR1

(2009) J. Fritz et al.   MOLECULAR AND CELLULAR BIOLOGY

Altered Nuclear Retention of mRNAs Containing Inverted Repeats in Human Embryonic Stem Cells: Functional Role of a Nuclear Noncoding RNA

(2009) Ling-Ling Chen et al.   MOLECULAR CELL

Identification of a selective nuclear import signal in adenosine deaminases acting on RNA

(2009) Stefan Maas et al.   NUCLEIC ACIDS RESEARCH

Novel Exon of Mammalian ADAR2 Extends Open Reading Frame

(2009) Stefan Maas et al.   PLoS One

RNA Editing Genes Associated with Extreme Old Age in Humans and with Lifespan in C. elegans

(2009) Paola Sebastiani et al.   PLoS One

An extra double-stranded RNA binding domain confers high activity to a squid RNA editing enzyme

(2009) J. P. Palavicini et al.   RNA

Down-regulation of RNA Editing in Pediatric Astrocytomas

(2008) Caterina Cenci et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Six novel mutations of theADAR1gene in patients with dyschromatosis symmetrica hereditaria: Histological observation and comparison of genotypes and clinical phenotypes

(2008) Taisuke KONDO et al.   JOURNAL OF DERMATOLOGY

Regulated RNA Editing and Functional Epistasis inShakerPotassium Channels

(2008) Lindsey Ingleby et al.   JOURNAL OF GENERAL PHYSIOLOGY

MicroRNA 21 Promotes Glioma Invasion by Targeting Matrix Metalloproteinase Regulators

(2008) G. Gabriely et al.   MOLECULAR AND CELLULAR BIOLOGY

ADAR1 is essential for the maintenance of hematopoiesis and suppression of interferon signaling

(2008) Jochen C Hartner et al.   NATURE IMMUNOLOGY

C. elegans and H. sapiens mRNAs with edited 3' UTRs are present on polysomes

(2008) H. A. Hundley et al.   RNA