ADAR1-mediated RNA editing is a novel oncogenic process in thyroid cancer and regulates miR-200 activity

Impaired microRNA processing by DICER1 downregulation endows thyroid cancer with increased aggressiveness

(2019) Julia Ramírez-Moya et al.   ONCOGENE

ADAR1 promotes the epithelial-to-mesenchymal transition and stem-like cell phenotype of oral cancer by facilitating oncogenic microRNA maturation

(2019) Xue Liu et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

miRNA-Directed Regulation of the Main Signaling Pathways in Thyroid Cancer

(2019) Julia Ramírez-Moya et al.   Frontiers in Endocrinology

MicroRNA-146b promotes PI3K/AKT pathway hyperactivation and thyroid cancer progression by targeting PTEN

(2018) Julia Ramírez-Moya et al.   ONCOGENE

ADARs and editing: The role of A-to-I RNA modification in cancer progression

(2018) Kajsa Fritzell et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Loss of ADAR1 in tumours overcomes resistance to immune checkpoint blockade

(2018) Jeffrey J. Ishizuka et al.   NATURE

Tumor-derived IFN triggers chronic pathway agonism and sensitivity to ADAR loss

(2018) Huayang Liu et al.   NATURE MEDICINE

Identification of ADAR1 adenosine deaminase dependency in a subset of cancer cells

(2018) Hugh S. Gannon et al.   Nature Communications

ADAR1 Editing and its Role in Cancer

(2018) Li-Di Xu et al.   Genes

Systematic characterization of A-to-I RNA editing hotspots in microRNAs across human cancers

(2017) Yumeng Wang et al.   GENOME RESEARCH

Trends in Thyroid Cancer Incidence and Mortality in the United States, 1974-2013

(2017) Hyeyeun Lim et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Key signaling pathways in thyroid cancer

(2017) Miguel A Zaballos et al.   JOURNAL OF ENDOCRINOLOGY

ADAR1 Activation Drives Leukemia Stem Cell Self-Renewal by Impairing Let-7 Biogenesis

(2016) Maria Anna Zipeto et al.   Cell Stem Cell

β-catenin signaling is required for RAS-driven thyroid cancer through PI3K activation

(2016) Ana Sastre-Perona et al.   Oncotarget

The Genomic Landscape and Clinical Relevance of A-to-I RNA Editing in Human Cancers

(2015) Leng Han et al.   CANCER CELL

The miR-146b-3p/PAX8/NIS Regulatory Circuit Modulates the Differentiation Phenotype and Function of Thyroid Cells during Carcinogenesis

(2015) G. Riesco-Eizaguirre et al.   CANCER RESEARCH

ZEB1: At the crossroads of epithelial-mesenchymal transition, metastasis and therapy resistance

(2015) Peijing Zhang et al.   CELL CYCLE

Three-Dimensional Cell Culture: A Breakthrough in Vivo

(2015) Delphine Antoni et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

An RNA editing fingerprint of cancer stem cell reprogramming

(2015) Leslie A Crews et al.   Journal of Translational Medicine

Reduced adenosine-to-inosine miR-455-5p editing promotes melanoma growth and metastasis

(2015) Einav Shoshan et al.   NATURE CELL BIOLOGY

A-to-I editing of coding and non-coding RNAs by ADARs

(2015) Kazuko Nishikura   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Elevated RNA Editing Activity Is a Major Contributor to Transcriptomic Diversity in Tumors

(2015) Nurit Paz-Yaacov et al.   Cell Reports

RNA Editome Imbalance in Hepatocellular Carcinoma

(2014) L. Qi et al.   CANCER RESEARCH

Integrated Genomic Characterization of Papillary Thyroid Carcinoma

(2014) Nishant Agrawal et al.   CELL

MiR-200, a new star miRNA in human cancer

(2013) Xiangling Feng et al.   CANCER LETTERS

Adenosine-to-Inosine RNA Editing Mediated by ADARs in Esophageal Squamous Cell Carcinoma

(2013) Y.-R. Qin et al.   CANCER RESEARCH

The Role of Epithelial Mesenchymal Transition Markers in Thyroid Carcinoma Progression

(2013) Celina Montemayor-Garcia et al.   ENDOCRINE PATHOLOGY

MicroRNA-mediated loss of ADAR1 in metastatic melanoma promotes tumor growth

(2013) Yael Nemlich et al.   JOURNAL OF CLINICAL INVESTIGATION

Deregulation of microRNA expression in thyroid neoplasias

(2013) Pierlorenzo Pallante et al.   Nature Reviews Endocrinology

Review of MiR-200b and cancer chemosensitivity

(2012) Bing Feng et al.   BIOMEDICINE & PHARMACOTHERAPY

Overexpression of ZEB1 associated with metastasis and invasion in patients with gastric carcinoma

(2012) Baoqing Jia et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Involvement of ZEB1 and E-cadherin in the invasion of lung squamous cell carcinoma

(2012) Jiaxing Zhang et al.   MOLECULAR BIOLOGY REPORTS

ADAR1 promotes malignant progenitor reprogramming in chronic myeloid leukemia

(2012) Q. Jiang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNAs as regulators of epithelial-mesenchymal transition

(2011) Philip A. Gregory et al.   CELL CYCLE

Overexpression of ZEB1 relates to metastasis and invasion in osteosarcoma

(2011) Aidong Shen et al.   JOURNAL OF SURGICAL ONCOLOGY

Downregulation of microRNAs directs the EMT and invasive potential of anaplastic thyroid carcinomas

(2010) J Braun et al.   ONCOGENE

ZEB1 represses E-cadherin and induces an EMT by recruiting the SWI/SNF chromatin-remodeling protein BRG1

(2010) E Sánchez-Tilló et al.   ONCOGENE

Large-scale mRNA sequencing determines global regulation of RNA editing during brain development

(2009) H. Wahlstedt et al.   GENOME RESEARCH

A Double-Negative Feedback Loop between ZEB1-SIP1 and the microRNA-200 Family Regulates Epithelial-Mesenchymal Transition

(2008) C. P. Bracken et al.   CANCER RESEARCH

The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2

(2008) S.-M. Park et al.   GENES & DEVELOPMENT

The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1

(2008) Philip A. Gregory et al.   NATURE CELL BIOLOGY

The microRNA-200 Family Regulates Epithelial to Mesenchymal Transition

(2008) Emily L. Paterson et al.   TheScientificWorldJOURNAL