Circadian clock genes promote glioma progression by affecting tumour immune infiltration and tumour cell proliferation

Targeting of immunosuppressive myeloid cells from glioblastoma patients by modulation of size and surface charge of lipid nanocapsules

(2020) Laura Pinton et al.   JOURNAL OF NANOBIOTECHNOLOGY

Adult Human Glioblastomas Harbor Radial Glia-like Cells

(2020) Rong Wang et al.   Stem Cell Reports

High Dimensional Mass Cytometry Analysis Reveals Characteristics of the Immunosuppressive Microenvironment in Diffuse Astrocytomas

(2020) Weilun Fu et al.   Frontiers in Oncology

Circadian clock and cancer: From a viewpoint of cellular differentiation

(2020) Yoshiki Tsuchiya et al.   INTERNATIONAL JOURNAL OF UROLOGY

Construction of a human cell landscape at single-cell level

(2020) Xiaoping Han et al.   NATURE

Modifying the tumour microenvironment and reverting tumour cells: New strategies for treating malignant tumours

(2020) Ya Qi Cheng et al.   CELL PROLIFERATION

Approaches to treat immune hot, altered and cold tumours with combination immunotherapies

(2019) Jérôme Galon et al.   NATURE REVIEWS DRUG DISCOVERY

ERK-mediated TIMELESS expression suppresses G2/M arrest in colon cancer cells

(2019) Beth K. Neilsen et al.   PLoS One

An Overview of the Polymorphisms of Circadian Genes Associated With Endocrine Cancer

(2019) Sonia Morales-Santana et al.   Frontiers in Endocrinology

Overexpression of Claspin and Timeless protects cancer cells from replication stress in a checkpoint-independent manner

(2019) Julien N. Bianco et al.   Nature Communications

Circadian Clocks and Cancer: Timekeeping Governs Cellular Metabolism

(2019) Amandine Verlande et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Circadian Clock Genes and the Transcriptional Architecture of the Clock Mechanism

(2019) Kimberly H. Cox et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Timeless-Stimulated miR-5188-FOXO1/β-Catenin-c-Jun Feedback Loop Promotes Stemness via Ubiquitination of β-Catenin in Breast Cancer

(2019) Yujiao Zou et al.   MOLECULAR THERAPY

Targeting Glioblastoma Stem Cells through Disruption of the Circadian Clock

(2019) Zhen Dong et al.   Cancer Discovery

Alterations to the circadian clock make brain tumours vulnerable

(2019) Guiomar Solanas et al.   NATURE

Circadian clock associates with tumor microenvironment in thoracic cancers

(2019) Yong Yang et al.   Aging-US

Rotating Night Shift work and Colorectal Cancer Risk in the Nurses' Health Studies

(2018) Kyriaki Papantoniou et al.   INTERNATIONAL JOURNAL OF CANCER

The analysis of deregulated expression of the timeless genes in gliomas

(2018) QianXue Chen et al.   Journal of Cancer Research and Therapeutics

Sleep and circadian disruption and incident breast cancer risk: An evidence-based and theoretical review

(2018) Laura B. Samuelsson et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Evolution of pallium, hippocampus, and cortical cell types revealed by single-cell transcriptomics in reptiles

(2018) Maria Antonietta Tosches et al.   SCIENCE

Pharmacological activation of REV-ERBs is lethal in cancer and oncogene-induced senescence

(2018) Gabriele Sulli et al.   NATURE

Deoxypodophyllotoxin triggers parthanatos in glioma cells via induction of excessive ROS

(2016) Diandong Ma et al.   CANCER LETTERS

Circadian Rhythm Disruption Promotes Lung Tumorigenesis

(2016) Thales Papagiannakopoulos et al.   Cell Metabolism

Dysregulation of metallothionein and circadian genes in human hepatocellular carcinoma

(2016) Huan Li et al.   CHRONOBIOLOGY INTERNATIONAL

Aberrant TIMELESS expression is associated with poor clinical survival and lymph node metastasis in early-stage cervical carcinoma

(2016) Weijing Zhang et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Knockdown of PREX2a inhibits the malignant phenotype of glioma cells

(2016) LIANG LIU et al.   Molecular Medicine Reports

Current and future strategies for treatment of glioma

(2016) Nancy Ann Oberheim Bush et al.   NEUROSURGICAL REVIEW

Circadian clock gene Per2 plays an important role in cell proliferation, apoptosis and cell cycle progression in human oral squamous cell carcinoma

(2016) QINGQING WANG et al.   ONCOLOGY REPORTS

Microglia inflammatory responses are controlled by an intrinsic circadian clock

(2015) Laura K. Fonken et al.   BRAIN BEHAVIOR AND IMMUNITY

The Molecular Signatures Database Hallmark Gene Set Collection

(2015) Arthur Liberzon et al.   Cell Systems

The epidemiology of glioma in adults: a "state of the science" review

(2014) Q. T. Ostrom et al.   NEURO-ONCOLOGY

Induction of the CLOCK Gene by E2-ERα Signaling Promotes the Proliferation of Breast Cancer Cells

(2014) Liyun Xiao et al.   PLoS One

GSVA: gene set variation analysis for microarray and RNA-Seq data

(2013) Sonja Hänzelmann et al.   BMC BIOINFORMATICS

Circadian gene Clock contributes to cell proliferation and migration of glioma and is directly regulated by tumor-suppressive miR-124

(2013) Aihua Li et al.   FEBS LETTERS

Spatiotemporal Dynamics of Intratumoral Immune Cells Reveal the Immune Landscape in Human Cancer

(2013) Gabriela Bindea et al.   IMMUNITY

Microenvironmental regulation of tumor progression and metastasis

(2013) Daniela F Quail et al.   NATURE MEDICINE

Bmal1 suppresses cancer cell invasion by blocking the phosphoinositide 3-kinase-Akt-MMP-2 signaling pathway

(2013) CHAN-HUN JUNG et al.   ONCOLOGY REPORTS

Inferring tumour purity and stromal and immune cell admixture from expression data

(2013) Kosuke Yoshihara et al.   Nature Communications

Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists

(2012) Laura A. Solt et al.   NATURE

clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters

(2012) Guangchuang Yu et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

Deregulated Expression of the Clock Genes in Gliomas

(2012) Zhijun Chen et al.   TECHNOLOGY IN CANCER RESEARCH & TREATMENT

GISTIC2.0 facilitates sensitive and confident localization of the targets of focal somatic copy-number alteration in human cancers

(2011) Craig H Mermel et al.   GENOME BIOLOGY

Systems Biology of Mammalian Circadian Clocks

(2010) Hideki Ukai et al.   Annual Review of Physiology

ConsensusClusterPlus: a class discovery tool with confidence assessments and item tracking

(2010) Matthew D. Wilkerson et al.   BIOINFORMATICS

Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1

(2010) Roel G.W. Verhaak et al.   CANCER CELL

In This Issue: Circadian Disruption and Cancer

(2009) Keith I. Block et al.   INTEGRATIVE CANCER THERAPIES

A Large Scale shRNA Barcode Screen Identifies the Circadian Clock Component ARNTL as Putative Regulator of the p53 Tumor Suppressor Pathway

(2009) Jasper Mullenders et al.   PLoS One

Therapeutic Targets in Malignant Glioblastoma Microenvironment

(2009) Mary Helen Barcellos-Hoff et al.   SEMINARS IN RADIATION ONCOLOGY