ERK-mediated TIMELESS expression suppresses G2/M arrest in colon cancer cells

Aberrant TIMELESS expression is associated with poor clinical survival and lymph node metastasis in early-stage cervical carcinoma

(2016) Weijing Zhang et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

KSR1 and EPHB4 Regulate Myc and PGC1β To Promote Survival of Human Colon Tumors

(2016) Jamie L. McCall et al.   MOLECULAR AND CELLULAR BIOLOGY

MYC Disrupts the Circadian Clock and Metabolism in Cancer Cells

(2015) Brian J. Altman et al.   Cell Metabolism

AMPK Promotes Aberrant PGC1β Expression To Support Human Colon Tumor Cell Survival

(2015) Kurt W. Fisher et al.   MOLECULAR AND CELLULAR BIOLOGY

Timeless Interacts with PARP-1 to Promote Homologous Recombination Repair

(2015) Si Xie et al.   MOLECULAR CELL

Morphological characterization of mammalian Timeless in the mouse brain development

(2015) Yutaka Inaguma et al.   NEUROSCIENCE RESEARCH

TIMELESS Forms a Complex with PARP1 Distinct from Its Complex with TIPIN and Plays a Role in the DNA Damage Response

(2015) Lauren M. Young et al.   Cell Reports

Potential cancer-related role of circadian gene TIMELESS suggested by expression profiling and in vitro analyses

(2013) Yingying Mao et al.   BMC CANCER

Separation of intra-S checkpoint protein contributions to DNA replication fork protection and genomic stability in normal human fibroblasts

(2013) Stephanie L. Smith-Roe et al.   CELL CYCLE

Timeless-Dependent DNA Replication-Coupled Recombination Promotes Kaposi's Sarcoma-Associated Herpesvirus Episome Maintenance and Terminal Repeat Stability

(2013) J. Dheekollu et al.   JOURNAL OF VIROLOGY

Human Tim-Tipin complex affects the biochemical properties of the replicative DNA helicase and DNA polymerases

(2013) W.-H. Cho et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Using Functional Signature Ontology (FUSION) to Identify Mechanisms of Action for Natural Products

(2013) M. B. Potts et al.   Science Signaling

Epigenetic and genetic features of 24 colon cancer cell lines

(2013) D Ahmed et al.   Oncogenesis

TIMELESSis overexpressed in lung cancer and its expression correlates with poor patient survival

(2012) Kenya Yoshida et al.   CANCER SCIENCE

Timeless preserves telomere length by promoting efficient DNA replication through human telomeres

(2012) Adam R. Leman et al.   CELL CYCLE

Clock Gene Expression Levels and Relationship With Clinical and Pathological Features in Colorectal Cancer Patients

(2011) G. Mazzoccoli et al.   CHRONOBIOLOGY INTERNATIONAL

The Replisome Pausing Factor Timeless Is Required for Episomal Maintenance of Latent Epstein-Barr Virus

(2011) J. Dheekollu et al.   JOURNAL OF VIROLOGY

Genetic and epigenetic associations of circadian geneTIMELESSand breast cancer risk

(2011) Alan Fu et al.   MOLECULAR CARCINOGENESIS

An Unexpected Role for the Clock Protein Timeless in Developmental Apoptosis

(2011) Linda P. O'Reilly et al.   PLoS One

Timeless Links Replication Termination to Mitotic Kinase Activation

(2011) Jayaraju Dheekollu et al.   PLoS One

Human Timeless and Tipin stabilize replication forks and facilitate sister-chromatid cohesion

(2010) A. R. Leman et al.   JOURNAL OF CELL SCIENCE

Immortalized Epithelial Cells Derived From Human Colon Biopsies Express Stem Cell Markers and Differentiate In Vitro

(2009) Andres I. Roig et al.   GASTROENTEROLOGY

Mammalian TIMELESS Is Required for ATM-dependent CHK2 Activation and G2/M Checkpoint Control

(2009) Xiaoming Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tim–Tipin dysfunction creates an indispensible reliance on the ATR–Chk1 pathway for continued DNA synthesis

(2009) Kevin D. Smith et al.   JOURNAL OF CELL BIOLOGY

Timeless Maintains Genomic Stability and Suppresses Sister Chromatid Exchange during Unperturbed DNA Replication

(2008) Karen A. Urtishak et al.   JOURNAL OF BIOLOGICAL CHEMISTRY