Tumor Reliance on Cytosolic versus Mitochondrial One-Carbon Flux Depends on Folate Availability
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Title
Tumor Reliance on Cytosolic versus Mitochondrial One-Carbon Flux Depends on Folate Availability
Authors
Keywords
folate cycle, one-carbon flux, cancer metabolism, serine hydroxymethyltransferase, SHMT, reduced folate carrier, mitochondria, physiologic medium, in vivo, metabolomics, isotope tracing
Journal
Cell Metabolism
Volume 33, Issue 1, Pages 190-198.e6
Publisher
Elsevier BV
Online
2020-12-16
DOI
10.1016/j.cmet.2020.12.002
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