FBXO44 promotes DNA replication-coupled repetitive element silencing in cancer cells

SUV39H1 represses the expression of cytotoxic T-lymphocyte effector genes to promote colon tumor immune evasion

(2019) Chunwan Lu et al.   Cancer Immunology Research

Genomic correlates of response to immune checkpoint blockade

(2019) Tanya E. Keenan et al.   NATURE MEDICINE

Chromatin landscapes reveal developmentally encoded transcriptional states that define human glioblastoma

(2019) Stephen C. Mack et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Proteomics of Melanoma Response to Immunotherapy Reveals Mitochondrial Dependence

(2019) Michal Harel et al.   CELL

Cytosolic DNA Sensing in Organismal Tumor Control

(2018) Claire Vanpouille-Box et al.   CANCER CELL

LSD1 Ablation Stimulates Anti-tumor Immunity and Enables Checkpoint Blockade

(2018) Wanqiang Sheng et al.   CELL

The Immune Landscape of Cancer

(2018) Vésteinn Thorsson et al.   IMMUNITY

The cGAS–cGAMP–STING pathway connects DNA damage to inflammation, senescence, and cancer

(2018) Tuo Li et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Chromosomal instability drives metastasis through a cytosolic DNA response

(2018) Samuel F. Bakhoum et al.   NATURE

N-methyladenine DNA Modification in Glioblastoma

(2018) Qi Xie et al.   CELL

Transposable Elements in Human Cancer: Causes and Consequences of Deregulation

(2017) Sumadi Anwar et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

cGAS surveillance of micronuclei links genome instability to innate immunity

(2017) Karen J. Mackenzie et al.   NATURE

Ten principles of heterochromatin formation and function

(2017) Robin C. Allshire et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Induction of H3K9me3 and DNA methylation by tethered heterochromatin factors inNeurospora crassa

(2017) Jordan D. Gessaman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TNFα blockade overcomes resistance to anti-PD-1 in experimental melanoma

(2017) Florie Bertrand et al.   Nature Communications

Mutational and putative neoantigen load predict clinical benefit of adoptive T cell therapy in melanoma

(2017) Martin Lauss et al.   Nature Communications

Resistance to checkpoint blockade therapy through inactivation of antigen presentation

(2017) Moshe Sade-Feldman et al.   Nature Communications

PRC2 and SWI/SNF Chromatin Remodeling Complexes in Health and Disease

(2016) Cigall Kadoch et al.   BIOCHEMISTRY

Epigenetic regulation of long noncoding RNA UCA1 by SATB1 in breast cancer

(2016) Jong-Joo Lee et al.   BMB Reports

Loss of IFN-γ Pathway Genes in Tumor Cells as a Mechanism of Resistance to Anti-CTLA-4 Therapy

(2016) Jianjun Gao et al.   CELL

An RB-EZH2 Complex Mediates Silencing of Repetitive DNA Sequences

(2016) Charles A. Ishak et al.   MOLECULAR CELL

Long Terminal Repeats: From Parasitic Elements to Building Blocks of the Transcriptional Regulatory Repertoire

(2016) Peter J. Thompson et al.   MOLECULAR CELL

Regulatory activities of transposable elements: from conflicts to benefits

(2016) Edward B. Chuong et al.   NATURE REVIEWS GENETICS

Mutations Associated with Acquired Resistance to PD-1 Blockade in Melanoma

(2016) Jesse M. Zaretsky et al.   NEW ENGLAND JOURNAL OF MEDICINE

deepTools2: a next generation web server for deep-sequencing data analysis

(2016) Fidel Ramírez et al.   NUCLEIC ACIDS RESEARCH

A rapid and efficient method to purify proteins at replication forks under native conditions

(2016) Kai Him Thomas Leung et al.   BIOTECHNIQUES

DNA-Demethylating Agents Target Colorectal Cancer Cells by Inducing Viral Mimicry by Endogenous Transcripts

(2015) David Roulois et al.   CELL

Inhibiting DNA Methylation Causes an Interferon Response in Cancer via dsRNA Including Endogenous Retroviruses

(2015) Katherine B. Chiappinelli et al.   CELL

Repeat DNA in genome organization and stability

(2015) Jan Padeken et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Two distinct modes for propagation of histone PTMs across the cell cycle

(2015) Constance Alabert et al.   GENES & DEVELOPMENT

A Role for Widely Interspaced Zinc Finger (WIZ) in Retention of the G9a Methyltransferase on Chromatin

(2015) Jeremy M. Simon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Association of the Xeroderma Pigmentosum Group D DNA Helicase (XPD) with Transcription Factor IIH Is Regulated by the Cytosolic Iron-Sulfur Cluster Assembly Pathway

(2015) Ajay A. Vashisht et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Oncogenic cancer/testis antigens: prime candidates for immunotherapy

(2015) Morten F. Gjerstorff et al.   Oncotarget

FBXO44-Mediated Degradation of RGS2 Protein Uniquely Depends on a Cullin 4B/DDB1 Complex

(2015) Benita Sjögren et al.   PLoS One

Transcriptional landscape of repetitive elements in normal and cancer human cells

(2014) Steven W Criscione et al.   BMC GENOMICS

Suv39h-Dependent H3K9me3 Marks Intact Retrotransposons and Silences LINE Elements in Mouse Embryonic Stem Cells

(2014) Aydan Bulut-Karslioglu et al.   MOLECULAR CELL

PD-1 blockade induces responses by inhibiting adaptive immune resistance

(2014) Paul C. Tumeh et al.   NATURE

Nascent chromatin capture proteomics determines chromatin dynamics during DNA replication and identifies unknown fork components

(2014) Constance Alabert et al.   NATURE CELL BIOLOGY

Molecular Mechanisms of DNA Replication Checkpoint Activation

(2014) Bénédicte Recolin et al.   Genes

GSVA: gene set variation analysis for microarray and RNA-Seq data

(2013) Sonja Hänzelmann et al.   BMC BIOINFORMATICS

Mechanisms and function of substrate recruitment by F-box proteins

(2013) Jeffrey R. Skaar et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

CRL4B promotes tumorigenesis by coordinating with SUV39H1/HP1/DNMT3A in DNA methylation-based epigenetic silencing

(2013) Y Yang et al.   ONCOGENE

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

CRL4B Catalyzes H2AK119 Monoubiquitination and Coordinates with PRC2 to Promote Tumorigenesis

(2012) Huili Hu et al.   CANCER CELL

Fast gapped-read alignment with Bowtie 2

(2012) Ben Langmead et al.   NATURE METHODS

Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks

(2012) Cole Trapnell et al.   Nature Protocols

VennDiagram: a package for the generation of highly-customizable Venn and Euler diagrams in R

(2011) Hanbo Chen et al.   BMC BIOINFORMATICS

A cell spot microarray method for production of high density siRNA transfection microarrays

(2011) Juha K Rantala et al.   BMC GENOMICS

CRL4Cdt2

(2011) Tarek Abbas et al.   CELL CYCLE

A model for mitotic inheritance of histone lysine methylation

(2011) Mo Xu et al.   EMBO REPORTS

Mi-2/NuRD complex function is required for normal S phase progression and assembly of pericentric heterochromatin

(2011) Jennifer K. Sims et al.   MOLECULAR BIOLOGY OF THE CELL

Interplay between oncogene-induced DNA damage response and heterochromatin in senescence and cancer

(2011) Raffaella Di Micco et al.   NATURE CELL BIOLOGY

A mobile threat to genome stability: The impact of non-LTR retrotransposons upon the human genome

(2010) Miriam K. Konkel et al.   SEMINARS IN CANCER BIOLOGY

DNA Methylation and Normal Chromosome Behavior in Neurospora Depend on Five Components of a Histone Methyltransferase Complex, DCDC

(2010) Zachary A. Lewis et al.   PLoS Genetics

RNA Interference Guides Histone Modification during the S Phase of Chromosomal Replication

(2008) Anna Kloc et al.   CURRENT BIOLOGY

Cell cycle control of centromeric repeat transcription and heterochromatin assembly

(2008) Ee Sin Chen et al.   NATURE