Novel artemisinin derivatives with potent anticancer activities and the anti-colorectal cancer effect by the mitochondria-mediated pathway

Artemisinin inhibits the replication of flaviviruses by promoting the type I interferon production

(2020) Xugang Wang et al.   ANTIVIRAL RESEARCH

Synthesis and biological activities of artemisinin-piperazine-dithiocarbamate derivatives

(2019) Jia-Ying Yu et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

A novel derivative of artemisinin inhibits cell proliferation and metastasis via down-regulation of cathepsin K in breast cancer

(2019) Xiangyu Gu et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Design and synthesis of novel artemisinin derivatives with potent activities against colorectal cancer in vitro and in vivo

(2019) Liang-Liang Wang et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Establishing Cation and Radical Donor Ability Scales of Electrophilic F, CF3, and SCF3 Transfer Reagents

(2019) Man Li et al.   ACCOUNTS OF CHEMICAL RESEARCH

Design, synthesis and biological evaluation of artemisinin derivatives containing fluorine atoms as anticancer agents

(2018) Shu Li et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis of novel ring-contracted artemisinin dimers with potent anticancer activities

(2018) Ning Zhang et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Chemical composition, in vitro anti-tumor activities and related mechanisms of the essential oil from the roots of Potentilla discolor

(2018) Jing Zhang et al.   INDUSTRIAL CROPS AND PRODUCTS

Oxytosis/Ferroptosis—(Re-) Emerging Roles for Oxidative Stress-Dependent Non-apoptotic Cell Death in Diseases of the Central Nervous System

(2018) Jan Lewerenz et al.   Frontiers in Neuroscience

Piperazine derivatives with central pharmacological activity used as therapeutic tools

(2018) Adriane F. Brito et al.   FUNDAMENTAL & CLINICAL PHARMACOLOGY

Exploration of novel piperazine or piperidine constructed non-covalent peptidyl derivatives as proteasome inhibitors

(2017) Rangxiao Zhuang et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Bis-Acetyl Carbazole: A Photoremovable Protecting Group for Sequential Release of Two Different Functional Groups and Its Application in Therapeutic Release

(2017) Yarra Venkatesh et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Artemisinin-A Gift from Traditional Chinese Medicine to the World (Nobel Lecture)

(2016) Youyou Tu   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

New 4-Acyl-1-phenylaminocarbonyl-2-phenylpiperazine Derivatives as Potential Inhibitors of Adenovirus Infection. Synthesis, Biological Evaluation, and Structure–activity Relationships

(2016) Javier Sánchez-Céspedes et al.   JOURNAL OF MEDICINAL CHEMISTRY

Dihydroartemisinin induces apoptosis preferentially via a Bim-mediated intrinsic pathway in hepatocarcinoma cells

(2015) Guiqi Qin et al.   APOPTOSIS

Small-Molecule Modulators of Methyl-Lysine Binding for the CBX7 Chromodomain

(2015) Chunyan Ren et al.   CHEMISTRY & BIOLOGY

Fluoroalkane thioheterocyclic derivatives and their antitumor activity

(2015) Guangxiao Li et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Applications of Fluorine in Medicinal Chemistry

(2015) Eric P. Gillis et al.   JOURNAL OF MEDICINAL CHEMISTRY

A Randomised, Double Blind, Placebo-Controlled Pilot Study of Oral Artesunate Therapy for Colorectal Cancer

(2015) Sanjeev Krishna et al.   EBioMedicine

Anti-inflammatory, Antioxidant and Antimicrobial Effects of Artemisinin Extracts fromArtemisia annuaL.

(2015) Wan-Su Kim et al.   KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY

Synthesis, in vitro antiplasmodial activity and cytotoxicity of a series of artemisinin–triazine hybrids and hybrid-dimers

(2014) Theunis T. Cloete et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Enhanced delivery of artemisinin and its analogues to cancer cells by their adducts with human serum transferrin

(2014) Yan Yang et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Antimicrobial Activity of Artemisinin and Precursor Derived fromIn VitroPlantlets ofArtemisia annuaL.

(2014) Suganthi Appalasamy et al.   Biomed Research International

Novel 5-anilinoquinazoline-8-nitro derivatives as inhibitors of VEGFR-2 tyrosine kinase: synthesis, biological evaluation and molecular docking

(2013) Liang Xi et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Anti-cancer activity of DHA on gastric cancer—an in vitro and in vivo study

(2013) Haijun Sun et al.   TUMOR BIOLOGY

Substituted phenoxypropyl-(R)-2-methylpyrrolidine aminomethyl ketones as histamine-3 receptor inverse agonists

(2012) Allison L. Zulli et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Absorption of the novel artemisinin derivatives artemisone and artemiside: Potential application of Pheroid™ technology

(2011) J. Dewald Steyn et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Characterization of Tunable Piperidine and Piperazine Carbamates as Inhibitors of Endocannabinoid Hydrolases

(2010) Jonathan Z. Long et al.   JOURNAL OF MEDICINAL CHEMISTRY

The Molecular Mechanism of Action of Artemisinin—The Debate Continues

(2010) Paul M. O’Neill et al.   MOLECULES