Piperazine derivatives with central pharmacological activity used as therapeutic tools

Atropinic (anticholinergic) burden in antipsychotic-treated patients

(2017) François Montastruc et al.   FUNDAMENTAL & CLINICAL PHARMACOLOGY

A new piperazine derivative: 1-(4-(3,5-di-tert-butyl-4-hydroxybenzyl) piperazin-1-yl)-2-methoxyethan-1-one with antioxidant and central activity

(2017) Adriane F. Brito et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Clozapine v. first- and second-generation antipsychotics in treatment-refractory schizophrenia: systematic review and meta-analysis

(2016) Dan Siskind et al.   BRITISH JOURNAL OF PSYCHIATRY

Piperazine derivatives for therapeutic use: a patent review (2010-present)

(2016) Anuj K. Rathi et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Xylopia aethiopica fruit extract exhibits antidepressant-like effect via interaction with serotonergic neurotransmission in mice

(2016) Robert P. Biney et al.   JOURNAL OF ETHNOPHARMACOLOGY

Involvement of the monoamine system in antidepressant-like properties of 4-(1-phenyl-1h-pyrazol-4-ylmethyl)-piperazine-1-carboxylic acid ethyl ester

(2015) Pablinny Moreira Galdino et al.   LIFE SCIENCES

PATHOPHYSIOLOGY OF DEPRESSION: DO WE HAVE ANY SOLID EVIDENCE OF INTEREST TO CLINICIANS?

(2015) GREGOR HASLER   World Psychiatry

Clozapine: a review of clinical practice guidelines and prescribing trends

(2014) Stephanie Warnez et al.   BMC Psychiatry

Update on 1-benzylpiperazine (BZP) party pills

(2013) Márcia Sá Monteiro et al.   ARCHIVES OF TOXICOLOGY

Cannabidiol reverses the mCPP-induced increase in marble-burying behavior

(2013) Mirella Nardo et al.   FUNDAMENTAL & CLINICAL PHARMACOLOGY

Neurobiology of Major Depressive Disorder

(2013) Rosa Villanueva   NEURAL PLASTICITY

New insights into pharmacological profile of LASSBio-579, a multi-target N-phenylpiperazine derivative active on animal models of schizophrenia

(2012) Gilda Neves et al.   BEHAVIOURAL BRAIN RESEARCH

Biotransformation of LASSBio-579 and pharmacological evaluation of p -hydroxylated metabolite a N -phenylpiperazine antipsychotic lead compound

(2012) Tatiana F. Gomes et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Central pharmacological activity of a new piperazine derivative: 4-(1-Phenyl-1h-pyrazol-4-ylmethyl)-piperazine-1-carboxylic acid ethyl ester

(2012) Adriane Ferreira de Brito et al.   LIFE SCIENCES

Piperazine compounds as drugs of abuse

(2011) M.D. Arbo et al.   DRUG AND ALCOHOL DEPENDENCE

GABAergic and nitriergic modulation by curcumin for its antianxiety-like activity in mice

(2010) Neeraj Gilhotra et al.   BRAIN RESEARCH

A comparison of 1-benzylpiperazine and methamphetamine in their acute effects on anxiety-related behavior of hooded rats

(2008) Cherie E. Herbert et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR