Mangiferin and organ fibrosis: A mini review

Mangiferin Alleviates Renal Interstitial Fibrosis in Streptozotocin-Induced Diabetic Mice through Regulating the PTEN/PI3K/Akt Signaling Pathway

(2020) Yanyan Song et al.   Journal of Diabetes Research

Mangiferin exert cardioprotective and anti-apoptotic effects in heart failure induced rats

(2020) Tiechao Jiang et al.   LIFE SCIENCES

Mangiferin activates Nrf2 to attenuate cardiac fibrosis via redistributing glutaminolysis-derived glutamate

(2020) Junna Song et al.   PHARMACOLOGICAL RESEARCH

Therapeutic effects of mangiferin on sepsis-associated acute lung and kidney injuries via the downregulation of vascular permeability and protection of inflammatory and oxidative damages

(2020) Dong Zhang et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Mangiferin attenuates bleomycin-induced pulmonary fibrosis in mice through inhibiting TLR4/p65 and TGF-β1/Smad2/3 pathway

(2019) Li Jia et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Fibrosis and alcohol-related liver disease

(2019) Carolin Lackner et al.   JOURNAL OF HEPATOLOGY

Towards better definition, quantification and treatment of fibrosis in heart failure. A scientific roadmap by the Committee of Translational Research of the Heart Failure Association (HFA) of the European Society of Cardiology

(2019) Rudolf A. de Boer et al.   EUROPEAN JOURNAL OF HEART FAILURE

Lymphangiogenesis in kidney and lymph node mediates renal inflammation and fibrosis

(2019) Guangchang Pei et al.   Science Advances

Inflammation and renal fibrosis: Recent developments on key signaling molecules as potential therapeutic targets

(2018) Wenshan Lv et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

The macrophage phenotype and inflammasome component NLRP3 contributes to nephrocalcinosis-related chronic kidney disease independent from IL-1–mediated tissue injury

(2018) Hans-Joachim Anders et al.   KIDNEY INTERNATIONAL

Natural products targeting ER stress pathway for the treatment of cardiovascular diseases

(2018) Ker Woon Choy et al.   PHARMACOLOGICAL RESEARCH

Mangiferin Ameliorates Cisplatin Induced Acute Kidney Injury by Upregulating Nrf-2 via the Activation of PI3K and Exhibits Synergistic Anticancer Activity With Cisplatin

(2018) Pritam Sadhukhan et al.   Frontiers in Pharmacology

Mangiferin attenuates cisplatin-induced acute kidney injury in rats mediating modulation of MAPK pathway

(2018) Anil Kumar Sahu et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Toll-like receptors in the pathogenesis of pulmonary fibrosis

(2017) Theodoros Karampitsakos et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Traditional Chinese medicine for pulmonary fibrosis therapy: Progress and future prospects

(2017) Liu-Cheng Li et al.   JOURNAL OF ETHNOPHARMACOLOGY

Antioxidants and NOX1/NOX4 inhibition blocks TGFβ1-induced CCN2 and α-SMA expression in dermal and gingival fibroblasts

(2017) Hannah Murphy-Marshman et al.   PLoS One

A 1H-NMR based metabolomics study of the intervention effect of mangiferin on hyperlipidemia hamsters induced by a high-fat diet

(2017) Fuchuan Guo et al.   Food & Function

Nrf2/HO-1 mediates the neuroprotective effect of mangiferin on early brain injury after subarachnoid hemorrhage by attenuating mitochondria-related apoptosis and neuroinflammation

(2017) Zefeng Wang et al.   Scientific Reports

The potential role of mangiferin in cancer treatment through its immunomodulatory, anti-angiogenic, apoptopic, and gene regulatory effects

(2016) Alberto J. Núñez Selles et al.   BIOFACTORS

Mangiferin: A xanthonoid with multipotent anti-inflammatory potential

(2016) Sukanya Saha et al.   BIOFACTORS

Mangiferin modulation of metabolism and metabolic syndrome

(2016) Ekaterina Vladimirovna Fomenko et al.   BIOFACTORS

Reactive oxygen species and fibrosis: further evidence of a significant liaison

(2016) Kati Richter et al.   CELL AND TISSUE RESEARCH

Mangiferin protect myocardial insults through modulation of MAPK/TGF-β pathways

(2016) Kapil Suchal et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Nonalcoholic Fatty Liver Disease

(2016) Rotonya M. Carr et al.   GASTROENTEROLOGY CLINICS OF NORTH AMERICA

Idiopathic pulmonary fibrosis: an Australian perspective

(2016) J. Prasad et al.   INTERNAL MEDICINE JOURNAL

Mango peel powder supplementation prevents oxidative stress, inflammation, and fibrosis in carbon tetrachloride induced hepatic dysfunction in rats

(2016) Anayt Ulla et al.   JOURNAL OF FOOD BIOCHEMISTRY

Mechanical control of cardiac myofibroblasts

(2016) Sander van Putten et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

The next generation of therapeutics for chronic kidney disease

(2016) Matthew D. Breyer et al.   NATURE REVIEWS DRUG DISCOVERY

Protective effect of polyphenols in an inflammatory process associated with experimental pulmonary fibrosis in mice

(2015) Daniela Impellizzeri et al.   BRITISH JOURNAL OF NUTRITION

Fibrosis — A Common Pathway to Organ Injury and Failure

(2015) Don C. Rockey et al.   NEW ENGLAND JOURNAL OF MEDICINE

Mangiferin supplementation improves serum lipid profiles in overweight patients with hyperlipidemia: a double-blind randomized controlled trial

(2015) Lixin Na et al.   Scientific Reports

Comparative Pharmacokinetic Study of Mangiferin After Oral Administration of Pure Mangiferin and US Patented Polyherbal Formulation to Rats

(2014) Ananth Kumar Kammalla et al.   AAPS PHARMSCITECH

Mangiferin Attenuates Renal Fibrosis Through Down-Regulation of Osteopontin in Diabetic Rats

(2014) Xia Zhu et al.   PHYTOTHERAPY RESEARCH

Mangiferin Attenuates Diabetic Nephropathy by Inhibiting Oxidative Stress Mediated Signaling Cascade, TNFα Related and Mitochondrial Dependent Apoptotic Pathways in Streptozotocin-Induced Diabetic Rats

(2014) Pabitra Bikash Pal et al.   PLoS One

Mangiferin treatment inhibits hepatic expression of acyl-coenzyme A:diacylglycerol acyltransferase-2 in fructose-fed spontaneously hypertensive rats: a link to amelioration of fatty liver

(2014) Xiaomang Xing et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Fibroblasts in fibrosis: novel roles and mediators

(2014) Ryan T. Kendall et al.   Frontiers in Pharmacology

Mangiferin mitigates diabetic cardiomyopathy in streptozotocin-diabetic rats

(2013) Jun Hou et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Renal Interstitial Infiltration and Tertiary Lymphoid Organ Neogenesis in IgA Nephropathy

(2013) G. Pei et al.   Clinical Journal of the American Society of Nephrology

Xanthones as Potential Antioxidants

(2013) S.S. Panda et al.   CURRENT MEDICINAL CHEMISTRY

Improving permeability and oral absorption of mangiferin by phospholipid complexation

(2013) Hequn Ma et al.   FITOTERAPIA

Soya phospholipid complex of mangiferin enhances its hepatoprotectivity by improving its bioavailability and pharmacokinetics

(2013) Sauvik Bhattacharyya et al.   JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE

Sustained Wnt/β-Catenin Signaling Rescues High Glucose Induction of Transforming Growth Factor-β1-Mediated Renal Fibrosis

(2012) Cheng Ho et al.   AMERICAN JOURNAL OF THE MEDICAL SCIENCES

Inhibition of high glucose-induced inflammatory response and macrophage infiltration by a novel curcumin derivative prevents renal injury in diabetic rats

(2012) Yong Pan et al.   BRITISH JOURNAL OF PHARMACOLOGY

Neuropharmacological effect of Mangiferin on brain cholinesterase and brain biogenic amines in the management of Alzheimer's disease

(2012) Siddaruda M. Biradar et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Mechanisms of fibrosis: therapeutic translation for fibrotic disease

(2012) Thomas A Wynn et al.   NATURE MEDICINE

Cardioprotective Effect of Mangiferin on Left Ventricular Remodeling in Rats

(2012) Dezhi Zheng et al.   PHARMACOLOGY

Mangiferin exerts hepatoprotective activity against D-galactosamine induced acute toxicity and oxidative/nitrosative stress via Nrf2–NFκB pathways

(2012) Joydeep Das et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Pharmacokinetic study of mangiferin in human plasma after oral administration

(2011) Shaoying Hou et al.   FOOD CHEMISTRY

Molecular and cellular mechanisms involved in cardiac remodeling after acute myocardial infarction

(2011) Gemma Vilahur et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Structure elucidation of in vivo and in vitro metabolites of mangiferin

(2011) Huihui Liu et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Myofibroblast differentiation during fibrosis: role of NAD(P)H oxidases

(2011) Jeffrey L. Barnes et al.   KIDNEY INTERNATIONAL

Scraping fibrosis: Expressway to the core of fibrosis

(2011) Wajahat Z Mehal et al.   NATURE MEDICINE

Critical role for osteopontin in diabetic nephropathy

(2010) Susanne B. Nicholas et al.   KIDNEY INTERNATIONAL

Transcription factors in the pathogenesis of diabetic nephropathy

(2009) Amber Paratore Sanchez et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

Determination of mangiferin in rat plasma by liquid–liquid extraction with UPLC–MS/MS

(2009) Dandan Han et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Regulation of glutathione synthesis

(2008) Shelly C. Lu   MOLECULAR ASPECTS OF MEDICINE

Salacia oblonga root decreases cardiac hypertrophy in Zucker diabetic fatty rats: inhibition of cardiac expression of angiotensin II type 1 receptor

(2007) T. H. Huang et al.   DIABETES OBESITY & METABOLISM

Cellular and molecular mechanisms of fibrosis

(2007) TA Wynn   JOURNAL OF PATHOLOGY

Protective effects of Mangifera indica L extract (Vimang), and its major component mangiferin, on iron-induced oxidative damage to rat serum and liver

(2007) Gilberto L. Pardo-Andreu et al.   PHARMACOLOGICAL RESEARCH