- Home
- Publications
- Publication Search
- Publication Details
Title
Mechanistic insights into KDM4A driven genomic instability
Authors
Keywords
-
Journal
BIOCHEMICAL SOCIETY TRANSACTIONS
Volume -, Issue -, Pages -
Publisher
Portland Press Ltd.
Online
2021-01-26
DOI
10.1042/bst20191219
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Targeting the USP1 dependent KDM4A protein stability as a potential prostate cancer therapy
- (2020) Shu‐Zhong Cui et al. CANCER SCIENCE
- Advances in histone demethylase KDM4 as cancer therapeutic targets
- (2020) Dong Hoon Lee et al. FASEB JOURNAL
- SETD2 Restricts Prostate Cancer Metastasis by Integrating EZH2 and AMPK Signaling Pathways
- (2020) Huairui Yuan et al. CANCER CELL
- Upregulation of JMJD2A promotes migration and invasion in bladder cancer through regulation of SLUG
- (2019) Fengyi Wang et al. ONCOLOGY REPORTS
- Recent insights into apoptosis and toxic autophagy: the roles of MDA-7/IL-24, a multidimensional anti-cancer therapeutic
- (2019) Luni Emdad et al. SEMINARS IN CANCER BIOLOGY
- Formate metabolism in health and disease
- (2019) Matthias Pietzke et al. Molecular Metabolism
- Engaging chromatin: PRC2 structure meets function
- (2019) Paul Chammas et al. BRITISH JOURNAL OF CANCER
- High-Throughput Quantitative Top-Down Proteomics: Histone H4
- (2019) Matthew V. Holt et al. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
- Histone Lysine Methylation Dynamics Control EGFR DNA Copy Number Amplification
- (2019) Thomas L Clarke et al. Cancer Discovery
- Small molecule KDM4s inhibitors as anti-cancer agents
- (2018) Hongzhi Lin et al. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
- The histone H4 proteoform dynamics in response to SUV4-20 inhibition reveals single molecule mechanisms of inhibitor resistance
- (2018) Tao Wang et al. Epigenetics & Chromatin
- The JmjN domain as a dimerization interface and a targeted inhibitor of KDM4 demethylase activity
- (2018) May Levin et al. Oncotarget
- CTCF-KDM4A complex correlates with histone modifications that negatively regulate CHD5 gene expression in cancer cell lines
- (2018) Lissania Guerra-Calderas et al. Oncotarget
- Cross-talk between Lysine-Modifying Enzymes Controls Site-Specific DNA Amplifications
- (2018) Sweta Mishra et al. CELL
- Mechanistic and structural studies of KDM-catalysed demethylation of histone 1 isotype 4 at lysine 26
- (2018) Louise J. Walport et al. FEBS LETTERS
- Examining the Roles of H3K4 Methylation States with Systematically Characterized Antibodies
- (2018) Rohan N. Shah et al. MOLECULAR CELL
- Timely double-strand break repair and pathway choice in pericentromeric heterochromatin depend on the histone demethylase dKDM4A
- (2018) Aniek Janssen et al. GENES & DEVELOPMENT
- A nucleosome-free region locally abrogates histone H1–dependent restriction of linker DNA accessibility in chromatin
- (2018) Laxmi Narayan Mishra et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- MiR-10a functions as a tumor suppressor in prostate cancer via targeting KDM4A
- (2018) Haiqi Mu et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Design of KDM4 Inhibitors with Antiproliferative Effects in Cancer Models
- (2017) Young K. Chen et al. ACS Medicinal Chemistry Letters
- H3K14ac is linked to methylation of H3K9 by the triple Tudor domain of SETDB1
- (2017) Renata Z. Jurkowska et al. Nature Communications
- SUMO modification of a heterochromatin histone demethylase JMJD2A enables viral gene transactivation and viral replication
- (2017) Wan-Shan Yang et al. PLoS Pathogens
- Dual Chromatin and Cytoskeletal Remodeling by SETD2
- (2016) In Young Park et al. CELL
- Silencing the epigenetic silencer KDM4A for TRAIL and DR5 simultaneous induction and antitumor therapy
- (2016) Junjian Wang et al. CELL DEATH AND DIFFERENTIATION
- Continual removal of H3K9 promoter methylation by Jmjd2 demethylases is vital for ESC self‐renewal and early development
- (2016) Marianne Terndrup Pedersen et al. EMBO JOURNAL
- Lgr4 promotes prostate tumorigenesis through the Jmjd2a/AR signaling pathway
- (2016) Jianwei Zhang et al. EXPERIMENTAL CELL RESEARCH
- Regulation of Transient Site-specific Copy Gain by MicroRNA
- (2016) Joshua C. Black et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Downregulation of KDM4A Suppresses the Survival of Glioma Cells by Promoting Autophagy
- (2016) Bo Wang et al. JOURNAL OF MOLECULAR NEUROSCIENCE
- Structural basis for activity regulation of MLL family methyltransferases
- (2016) Yanjing Li et al. NATURE
- Reader domain specificity and lysine demethylase-4 family function
- (2016) Zhangli Su et al. Nature Communications
- Acetylation Mimics Within a Single Nucleosome Alter Local DNA Accessibility In Compacted Nucleosome Arrays
- (2016) Laxmi N. Mishra et al. Scientific Reports
- KDM4A Coactivates E2F1 to Regulate the PDK-Dependent Metabolic Switch between Mitochondrial Oxidation and Glycolysis
- (2016) Ling-Yu Wang et al. Cell Reports
- Too little O2Too much gain
- (2015) Joshua C Black et al. CELL CYCLE
- Emerging roles of lysine methylation on non-histone proteins
- (2015) Xi Zhang et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Rph1/KDM4 Mediates Nutrient-Limitation Signaling that Leads to the Transcriptional Induction of Autophagy
- (2015) Amélie Bernard et al. CURRENT BIOLOGY
- Advances in the development of histone lysine demethylase inhibitors
- (2015) Tamara Maes et al. CURRENT OPINION IN PHARMACOLOGY
- Hypoxia drives transient site-specific copy gain and drug-resistant gene expression
- (2015) Joshua C. Black et al. GENES & DEVELOPMENT
- Jumonji domain containing 2A predicts prognosis and regulates cell growth in lung cancer depending on miR-150
- (2015) WEIHUA XU et al. ONCOLOGY REPORTS
- Targeting histone lysine methylation in cancer
- (2015) John McGrath et al. PHARMACOLOGY & THERAPEUTICS
- Lysine Demethylase KDM4A Associates with Translation Machinery and Regulates Protein Synthesis
- (2015) C. Van Rechem et al. Cancer Discovery
- Overexpression of KDM4 lysine demethylases disrupts the integrity of the DNA mismatch repair pathway
- (2015) S. W. Awwad et al. Biology Open
- JMJD2A predicts prognosis and regulates cell growth in human gastric cancer
- (2014) Cheng-En Hu et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Interpreting the language of histone and DNA modifications
- (2014) Scott B. Rothbart et al. Biochimica et Biophysica Acta-Gene Regulatory Mechanisms
- A Cell-Permeable Ester Derivative of the JmjC Histone Demethylase Inhibitor IOX1
- (2014) Rachel Schiller et al. ChemMedChem
- The Demethylase JMJD2C Localizes to H3K4me3-Positive Transcription Start Sites and Is Dispensable for Embryonic Development
- (2014) M. T. Pedersen et al. MOLECULAR AND CELLULAR BIOLOGY
- PhosphoSitePlus, 2014: mutations, PTMs and recalibrations
- (2014) Peter V. Hornbeck et al. NUCLEIC ACIDS RESEARCH
- Erasers of Histone Acetylation: The Histone Deacetylase Enzymes
- (2014) E. Seto et al. Cold Spring Harbor Perspectives in Biology
- SETD2-Dependent Histone H3K36 Trimethylation Is Required for Homologous Recombination Repair and Genome Stability
- (2014) Sophia X. Pfister et al. Cell Reports
- The Histone Mark H3K36me3 Regulates Human DNA Mismatch Repair through Its Interaction with MutSα
- (2013) Feng Li et al. CELL
- KDM4A Lysine Demethylase Induces Site-Specific Copy Gain and Rereplication of Regions Amplified in Tumors
- (2013) Joshua C. Black et al. CELL
- Regulation of nucleosome dynamics by histone modifications
- (2013) Gabriel E Zentner et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- H3K56me3 Is a Novel, Conserved Heterochromatic Mark That Largely but Not Completely Overlaps with H3K9me3 in Both Regulation and Localization
- (2013) Antonia P. M. Jack et al. PLoS One
- Epigenetic Activation of AP1 Promotes Squamous Cell Carcinoma Metastasis
- (2013) X. Ding et al. Science Signaling
- 5-Carboxy-8-hydroxyquinoline is a broad spectrum 2-oxoglutarate oxygenase inhibitor which causes iron translocation
- (2013) Richard J. Hopkinson et al. Chemical Science
- A small molecule modulates Jumonji histone demethylase activity and selectively inhibits cancer growth
- (2013) Lei Wang et al. Nature Communications
- Set2 mediated H3 lysine 36 methylation: regulation of transcription elongation and implications in organismal development
- (2013) Swaminathan Venkatesh et al. Wiley Interdisciplinary Reviews-Developmental Biology
- RNF8- and RNF168-dependent degradation of KDM4A/JMJD2A triggers 53BP1 recruitment to DNA damage sites
- (2012) Frédérick A Mallette et al. EMBO JOURNAL
- Oncogenic features of the JMJD2A histone demethylase in breast cancer
- (2012) WILLIAM L. BERRY et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Understanding the language of Lys36 methylation at histone H3
- (2012) Eric J. Wagner et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Structural and Functional Analysis of JMJD2D Reveals Molecular Basis for Site-Specific Demethylation among JMJD2 Demethylases
- (2012) Swathi Krishnan et al. STRUCTURE
- JMJD2A Promotes Cellular Transformation by Blocking Cellular Senescence through Transcriptional Repression of the Tumor Suppressor CHD5
- (2012) Frédérick A. Mallette et al. Cell Reports
- Structural and Evolutionary Basis for the Dual Substrate Selectivity of Human KDM4 Histone Demethylase Family
- (2011) Lars Hillringhaus et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The SKP1-Cul1-F-box and Leucine-rich Repeat Protein 4 (SCF-FbxL4) Ubiquitin Ligase Regulates Lysine Demethylase 4A (KDM4A)/Jumonji Domain-containing 2A (JMJD2A) Protein
- (2011) Capucine Van Rechem et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The JMJD2A demethylase regulates apoptosis and proliferation in colon cancer cells
- (2011) Tae-Dong Kim et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Apoptosis in cancer: from pathogenesis to treatment
- (2011) Rebecca SY Wong JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- SCFFBXO22 Regulates Histone H3 Lysine 9 and 36 Methylation Levels by Targeting Histone Demethylase KDM4A for Ubiquitin-Mediated Proteasomal Degradation
- (2011) M.-K. M. Tan et al. MOLECULAR AND CELLULAR BIOLOGY
- Systems-wide proteomic characterization of combinatorial post-translational modification patterns
- (2010) Nicolas L Young et al. Expert Review of Proteomics
- Structural Characterization of Formaldehyde-Induced Cross-Links Between Amino Acids and Deoxynucleosides and Their Oligomers
- (2010) Kun Lu et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Quantitative proteomics reveals direct and indirect alterations in the histone code following methyltransferase knockdown
- (2010) Mariana D. Plazas-Mayorca et al. Molecular BioSystems
- Histone Demethylation and Timely DNA Replication
- (2010) Erica L. Gerace et al. MOLECULAR CELL
- Conserved Antagonism between JMJD2A/KDM4A and HP1γ during Cell Cycle Progression
- (2010) Joshua C. Black et al. MOLECULAR CELL
- The landscape of somatic copy-number alteration across human cancers
- (2010) Rameen Beroukhim et al. NATURE
- Lys-N and Trypsin Cover Complementary Parts of the Phosphoproteome in a Refined SCX-Based Approach
- (2009) Sharon Gauci et al. ANALYTICAL CHEMISTRY
- Genome-Wide Views of Chromatin Structure
- (2009) Oliver J. Rando et al. Annual Review of Biochemistry
- Identification of non-histone substrates for JMJD2A–C histone demethylases
- (2009) V.K. Chaithanya Ponnaluri et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Multiple SET Methyltransferases Are Required to Maintain Normal Heterochromatin Domains in the Genome of Drosophila melanogaster
- (2009) B. Brower-Toland et al. GENETICS
- Cellular radiosensitivity: How much better do we understand it?
- (2009) Penny Jeggo et al. INTERNATIONAL JOURNAL OF RADIATION BIOLOGY
- High Throughput Characterization of Combinatorial Histone Codes
- (2009) Nicolas L. Young et al. MOLECULAR & CELLULAR PROTEOMICS
- Protein Arginine Methylation in Mammals: Who, What, and Why
- (2009) Mark T. Bedford et al. MOLECULAR CELL
- The cancer genome
- (2009) Michael R. Stratton et al. NATURE
- Enzymatic and structural insights for substrate specificity of a family of jumonji histone lysine demethylases
- (2009) John R Horton et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started