Hyaloid Vasculature as a Major Source of STAT3 + (Signal Transducer and Activator of Transcription 3) Myeloid Cells for Pathogenic Retinal Neovascularization in Oxygen-Induced Retinopathy

STAT3 activation in circulating myeloid-derived cells contributes to retinal microvascular dysfunction in diabetes

(2019) Mei Chen et al.   Journal of Neuroinflammation

Cytokine Signaling Protein 3 Deficiency in Myeloid Cells Promotes Retinal Degeneration and Angiogenesis through Arginase-1 Up-Regulation in Experimental Autoimmune Uveoretinitis

(2018) Mei Chen et al.   AMERICAN JOURNAL OF PATHOLOGY

Antagonising Wnt/β-catenin signalling ameliorates lens-capsulotomy-induced retinal degeneration in a mouse model of diabetes

(2018) Jose R. Hombrebueno et al.   DIABETOLOGIA

Histochemical characteristics of regressing vessels in the hyaloid vascular system of neonatal mice: Novel implication for vascular atrophy

(2018) Ayuko Kishimoto et al.   EXPERIMENTAL EYE RESEARCH

Myeloid cells contribute indirectly to VEGF expression upon hypoxia via activation of Müller cells

(2018) Christina Nürnberg et al.   EXPERIMENTAL EYE RESEARCH

Pathophysiology, screening and treatment of ROP: A multi-disciplinary perspective

(2018) Tailoi Chan-Ling et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Hypoxia-Induced Activation of JAK/STAT3 Signaling Pathway Promotes Trophoblast Cell Viability and Angiogenesis in Preeclampsia

(2017) Chengfang Xu et al.   MEDICAL SCIENCE MONITOR

STAT3 Activation in Circulating Monocytes Contributes to Neovascular Age-Related Macular Degeneration

(2016) M. Chen et al.   CURRENT MOLECULAR MEDICINE

Developmental regression of hyaloid vasculature is triggered by neurons

(2016) Yusuke Yoshikawa et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Newly Formed Endothelial Cells Regulate Myeloid Cell Activity Following Spinal Cord Injury via Expression of CD200 Ligand

(2016) Merav Cohen et al.   JOURNAL OF NEUROSCIENCE

Myeloid-Derived Vascular Endothelial Growth Factor and Hypoxia-Inducible Factor Are Dispensable for Ocular Neovascularization

(2015) Sidath E. Liyanage et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Emerging translational approaches to target STAT3 signalling and its impact on vascular disease

(2015) Jochen Dutzmann et al.   CARDIOVASCULAR RESEARCH

Understanding the Mysterious M2 Macrophage through Activation Markers and Effector Mechanisms

(2015) Tamás Rőszer   MEDIATORS OF INFLAMMATION

SOCS3 in retinal neurons and glial cells suppresses VEGF signaling to prevent pathological neovascular growth

(2015) Ye Sun et al.   Science Signaling

Selective Interference Targeting of Lnk in Umbilical Cord-Derived Late Endothelial Progenitor Cells Improves Vascular Repair, Following Hind Limb Ischemic Injury, via Regulation of JAK2/STAT3 Signaling

(2015) Sang Hun Lee et al.   STEM CELLS

Sustained intraocular VEGF neutralization results in retinal neurodegeneration in the Ins2Akita diabetic mouse

(2015) Jose R. Hombrebueno et al.   Scientific Reports

SOCS3 in retinal neurons and glial cells suppresses VEGF signaling to prevent pathological neovascular growth

(2015) Ye Sun et al.   Science Signaling

SOCS3 Deficiency in Myeloid Cells Promotes Tumor Development: Involvement of STAT3 Activation and Myeloid-Derived Suppressor Cells

(2015) H. Yu et al.   Cancer Immunology Research

Multiple regulation pathways and pivotal biological functions of STAT3 in cancer

(2015) Jie Yuan et al.   Scientific Reports

A Novel Small Molecule, LLL12, Inhibits STAT3 Phosphorylation and Activities and Exhibits Potent Growth-Suppressive Activity in Human Cancer Cells

(2015) Li Lin et al.   NEOPLASIA

Incidence and treatment of retinopathy of prematurity in England between 1990 and 2011: database study

(2014) Sally L Painter et al.   BRITISH JOURNAL OF OPHTHALMOLOGY

Loss of Synaptic Connectivity, Particularly in Second Order Neurons Is a Key Feature of Diabetic Retinal Neuropathy in the Ins2Akita Mouse

(2014) Jose R. Hombrebueno et al.   PLoS One

Intravitreal Injection of Normal Saline Induces Retinal Degeneration in the C57BL/6J Mouse

(2014) Jose R. Hombrebueno et al.   Translational Vision Science & Technology

Anti-inflammatory M2, but not pro-inflammatory M1 macrophages promote angiogenesis in vivo

(2013) Nadine Jetten et al.   ANGIOGENESIS

The role of immune-related myeloid cells in angiogenesis

(2013) Sarah E.J. Chambers et al.   IMMUNOBIOLOGY

Seven-Year Outcomes in Ranibizumab-Treated Patients in ANCHOR, MARINA, and HORIZON

(2013) Soraya Rofagha et al.   OPHTHALMOLOGY

Preterm-associated visual impairment and estimates of retinopathy of prematurity at regional and global levels for 2010

(2013) Hannah Blencowe et al.   PEDIATRIC RESEARCH

Critical and Independent Role for SOCS3 in Either Myeloid or T Cells in Resistance to Mycobacterium tuberculosis

(2013) Berit Carow et al.   PLoS Pathogens

VEGF-Mediated STAT3 Activation Inhibits Retinal Vascularization by Down-Regulating Local Erythropoietin Expression

(2012) Haibo Wang et al.   AMERICAN JOURNAL OF PATHOLOGY

SOCS3 is an endogenous inhibitor of pathologic angiogenesis

(2012) A. Stahl et al.   BLOOD

Morphological and Functional Changes in the Retina after Chronic Oxygen-Induced Retinopathy

(2012) Shinsuke Nakamura et al.   PLoS One

Signal transducer and activator of transcription-3/suppressor of cytokine signaling-3 (STAT3/SOCS3) axis in myeloid cells regulates neuroinflammation

(2012) H. Qin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A novel STAT3 inhibitor, S3I-201, attenuates renal interstitial fibroblast activation and interstitial fibrosis in obstructive nephropathy

(2010) Maoyin Pang et al.   KIDNEY INTERNATIONAL

Interleukin-10 Promotes Pathological Angiogenesis by Regulating Macrophage Response to Hypoxia during Development

(2008) Dru S. Dace et al.   PLoS One