Role of specialized pro-resolving lipid mediators and their receptors in virus infection: a promising therapeutic strategy for SARS-CoV-2 cytokine storm

Concurrent Control of KSHV Life Cycle through Chromatin Modulation and Host Hedgehog Signaling: A New Prospect to the Therapeutic Potential of Lipoxin A4

(2020) Kumari Asha et al.   JOURNAL OF VIROLOGY

The species Severe acute respiratory syndrome-related coronavirus: classifying 2019-nCoV and naming it SARS-CoV-2

(2020)   Nature Microbiology

Inflammation resolution: a dual-pronged approach to averting cytokine storms in COVID-19?

(2020) Dipak Panigrahy et al.   CANCER AND METASTASIS REVIEWS

Predicting mortality due to SARS-CoV-2: A mechanistic score relating obesity and diabetes to COVID-19 outcomes in Mexico

(2020) Omar Yaxmehen Bello-Chavolla et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

First total synthesis of the pro-resolving lipid mediator 7(S),12(R),13(S)-Resolvin T2 and its 13(R)-epimer

(2020) Ana R. Rodriguez et al.   TETRAHEDRON LETTERS

Potential benefits and risks of omega-3 fatty acids supplementation to patients with COVID-19

(2020) Marcelo M. Rogero et al.   FREE RADICAL BIOLOGY AND MEDICINE

Obesity-Driven Deficiencies of Specialized Pro-resolving Mediators May Drive Adverse Outcomes During SARS-CoV-2 Infection

(2020) Anandita Pal et al.   Frontiers in Immunology

Decoding Susceptibility to Respiratory Viral Infections and Asthma Inception in Children

(2020) James F. Read et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Parenteral fish oil: An adjuvant pharmacotherapy for coronavirus disease 2019?

(2020) Raquel S. Torrinhas et al.   NUTRITION

Protective effects of GPR37 via regulation of inflammation and multiple cell death pathways after ischemic stroke in mice

(2019) Myles R. McCrary et al.   FASEB JOURNAL

Maresin 1 activates LGR6 receptor promoting phagocyte immunoresolvent functions

(2019) Nan Chiang et al.   JOURNAL OF CLINICAL INVESTIGATION

Cytokines and serum amyloid A in the pathogenesis of hepatitis C virus infection

(2019) Sara Abouelasrar Salama et al.   CYTOKINE & GROWTH FACTOR REVIEWS

GPR101 mediates the pro-resolving actions of RvD5n-3 DPA in arthritis and infections

(2019) Magdalena B. Flak et al.   JOURNAL OF CLINICAL INVESTIGATION

First total syntheses of the pro-resolving lipid mediators 7(S),13(R),20(S)-Resolvin T1 and 7(S),13(R)-Resolvin T4

(2019) Ana R. Rodriguez et al.   TETRAHEDRON LETTERS

GPR37 regulates macrophage phagocytosis and resolution of inflammatory pain

(2018) Sangsu Bang et al.   JOURNAL OF CLINICAL INVESTIGATION

Resolvin E1, but not resolvins E2 and E3, promotes fMLF-induced ROS generation in human neutrophils

(2018) Yuka Unno et al.   FEBS LETTERS

Epithelial-mesenchymal transition: Initiation by cues from chronic inflammatory tumor microenvironment and termination by anti-inflammatory compounds and specialized pro-resolving lipids

(2018) Chang Hoon Lee   BIOCHEMICAL PHARMACOLOGY

Lipoxin B4 Enhances Human Memory B Cell Antibody Production via Upregulating Cyclooxygenase-2 Expression

(2018) Nina Kim et al.   JOURNAL OF IMMUNOLOGY

Total Synthesis of the Antidiabetic (Type 2) Lipid Mediator Protectin DX/PDX

(2018) Jean-Yves Sancéau et al.   JOURNAL OF ORGANIC CHEMISTRY

Resolving Viral-Induced Secondary Bacterial Infection in COPD: A Concise Review

(2018) Hao Wang et al.   Frontiers in Immunology

Frontline Science: Aspirin-triggered resolvin D1 controls herpes simplex virus-induced corneal immunopathology

(2017) Naveen K. Rajasagi et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Structural elucidation and physiologic functions of specialized pro-resolving mediators and their receptors

(2017) Nan Chiang et al.   MOLECULAR ASPECTS OF MEDICINE

Resolution of Acute Inflammation and the Role of Resolvins in Immunity, Thrombosis, and Vascular Biology

(2016) Brian E. Sansbury et al.   CIRCULATION RESEARCH

DHA- and EPA-derived resolvins, protectins, and maresins in airway inflammation

(2016) Melody G. Duvall et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Novel Resolvin D2 Receptor Axis in Infectious Inflammation

(2016) Nan Chiang et al.   JOURNAL OF IMMUNOLOGY

Resolvin D1 Dampens Pulmonary Inflammation and Promotes Clearance of NontypeableHaemophilus influenzae

(2016) Amanda Croasdell et al.   JOURNAL OF IMMUNOLOGY

Resolvin D1 Polarizes Primary Human Macrophages toward a Proresolution Phenotype through GPR32

(2016) Mattia Schmid et al.   JOURNAL OF IMMUNOLOGY

Formyl Peptide Receptor 2 Plays a Deleterious Role During Influenza A Virus Infections

(2016) Sergey Tcherniuk et al.   JOURNAL OF INFECTIOUS DISEASES

Resolution of inflammation: a new therapeutic frontier

(2016) James N. Fullerton et al.   NATURE REVIEWS DRUG DISCOVERY

Opportunistic Infections in HIV-Infected Patients Differ Strongly in Frequencies and Spectra between Patients with Low CD4+ Cell Counts Examined Postmortem and Compensated Patients Examined Antemortem Irrespective of the HAART Era

(2016) Marta K. Powell et al.   PLoS One

Dihydroxylated E,E,Z-docosatrienes. An overview of their synthesis and biological significance

(2016) Laurence Balas et al.   PROGRESS IN LIPID RESEARCH

G protein-coupled receptor 37 is a negative regulator of oligodendrocyte differentiation and myelination

(2016) Hyun-Jeong Yang et al.   Nature Communications

Resolvin D4 stereoassignment and its novel actions in host protection and bacterial clearance

(2016) Jeremy W. Winkler et al.   Scientific Reports

Role of omega-3 PUFA-derived mediators, the protectins, in influenza virus infection

(2015) Yumiko Imai   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Lipoxins and aspirin-triggered lipoxins in resolution of inflammation

(2015) Mario Romano et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Maresin 1 Biosynthesis and Proresolving Anti-infective Functions with Human-Localized Aggressive Periodontitis Leukocytes

(2015) Chin-Wei Wang et al.   INFECTION AND IMMUNITY

Identification of resolvin D2 receptor mediating resolution of infections and organ protection

(2015) Nan Chiang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The role of parkinson's disease-associated receptor GPR37 in the hippocampus: functional interplay with the adenosinergic system

(2015) João P. Lopes et al.   JOURNAL OF NEUROCHEMISTRY

Maresin 1 Inhibits TRPV1 in Temporomandibular Joint-Related Trigeminal Nociceptive Neurons and TMJ Inflammation-Induced Synaptic Plasticity in the Trigeminal Nucleus

(2015) Chul-Kyu Park   MEDIATORS OF INFLAMMATION

Elucidation of novel 13-series resolvins that increase with atorvastatin and clear infections

(2015) Jesmond Dalli et al.   NATURE MEDICINE

The resolution of inflammation: Principles and challenges

(2015) Sarah E. Headland et al.   SEMINARS IN IMMUNOLOGY

Maresin-like Lipid Mediators Are Produced by Leukocytes and Platelets and Rescue Reparative Function of Diabetes-Impaired Macrophages

(2014) Song Hong et al.   CHEMISTRY & BIOLOGY

A Versatile and Stereocontrolled Total Synthesis of Dihydroxylated Docosatrienes Containing a ConjugatedE,E,Z-Triene

(2014) Gandrath Dayaker et al.   CHEMISTRY-A EUROPEAN JOURNAL

Impact of Resolvin E1 on Murine Neutrophil Phagocytosis in Type 2 Diabetes

(2014) Bruno S. Herrera et al.   INFECTION AND IMMUNITY

GPR18 is required for a normal CD8αα intestinal intraepithelial lymphocyte compartment

(2014) Xiaoming Wang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Resolvin E1 Metabolome in Local Inactivation during Inflammation-Resolution

(2014) S. Hong et al.   JOURNAL OF IMMUNOLOGY

Resolvin D1 Attenuates Polyinosinic-Polycytidylic Acid–Induced Inflammatory Signaling in Human Airway Epithelial Cells via TAK1

(2014) Hsi-Min Hsiao et al.   JOURNAL OF IMMUNOLOGY

Maresin Biosynthesis and Identification of Maresin 2, a New Anti-Inflammatory and Pro-Resolving Mediator from Human Macrophages

(2014) Bin Deng et al.   PLoS One

Lipid Mediators in the Resolution of Inflammation

(2014) Charles N. Serhan et al.   Cold Spring Harbor Perspectives in Biology

Mechanisms of HCV-induced liver cancer: What did we learn from in vitro and animal studies?

(2013) Ivan Rusyn et al.   CANCER LETTERS

The Lipid Mediator Protectin D1 Inhibits Influenza Virus Replication and Improves Severe Influenza

(2013) Masayuki Morita et al.   CELL

Lipidomic Profiling of Influenza Infection Identifies Mediators that Induce and Resolve Inflammation

(2013) Vincent C. Tam et al.   CELL

Resolvin D3 and Aspirin-Triggered Resolvin D3 Are Potent Immunoresolvents

(2013) Jesmond Dalli et al.   CHEMISTRY & BIOLOGY

Lipoxin A4modulates adaptive immunity by decreasing memory B-cell responses via an ALX/FPR2-dependent mechanism

(2013) Sesquile Ramon et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The novel 13S,14S-epoxy-maresin is converted by human macrophages to maresin 1 (MaR1), inhibits leukotriene A4 hydrolase (LTA4H), and shifts macrophage phenotype

(2013) Jesmond Dalli et al.   FASEB JOURNAL

Resolvin D1 inhibits TGF-β1-induced epithelial mesenchymal transition of A549 lung cancer cells via lipoxin A4 receptor/formyl peptide receptor 2 and GPR32

(2013) Hye Ja Lee et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Role of the lipoxygenase pathway in RSV-induced alternatively activated macrophages leading to resolution of lung pathology

(2013) K A Shirey et al.   Mucosal Immunology

Influenza — Time to Target the Host?

(2013) J. Kenneth Baillie et al.   NEW ENGLAND JOURNAL OF MEDICINE

Ligand-specific conformational change of the G-protein-coupled receptor ALX/FPR2 determines proresolving functional responses

(2013) S. N. Cooray et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Novel n-3 Immunoresolvents: Structures and Actions

(2013) Jesmond Dalli et al.   Scientific Reports

Resolvins as new fascinating drug candidates for inflammatory diseases

(2012) Chang Hoon Lee   ARCHIVES OF PHARMACAL RESEARCH

Resolvin D1 Limits Polymorphonuclear Leukocyte Recruitment to Inflammatory Loci

(2012) Lucy V. Norling et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

GPR18 in microglia: implications for the CNS and endocannabinoid system signalling

(2012) D McHugh   BRITISH JOURNAL OF PHARMACOLOGY

Identification and Structure Determination of Novel Anti-inflammatory Mediator Resolvin E3, 17,18-Dihydroxyeicosapentaenoic Acid

(2012) Yosuke Isobe et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Resolvin E2 Formation and Impact in Inflammation Resolution

(2012) S. F. Oh et al.   JOURNAL OF IMMUNOLOGY

Infection regulates pro-resolving mediators that lower antibiotic requirements

(2012) Nan Chiang et al.   NATURE

Mutation in Parkinson Disease-Associated, G-Protein-Coupled Receptor 37 (GPR37/PaelR) Is Related to Autism Spectrum Disorder

(2012) Eriko Fujita-Jimbo et al.   PLoS One

Serum amyloid A opposes lipoxin A4 to mediate glucocorticoid refractory lung inflammation in chronic obstructive pulmonary disease

(2012) S. Bozinovski et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Omega-3 fatty acids in anti-inflammation (pro-resolution) and GPCRs

(2012) Dong-Soon Im   PROGRESS IN LIPID RESEARCH

Resolvin D1 attenuates inflammation in lipopolysaccharide-induced acute lung injury through a process involving the PPARγ/NF-κB pathway

(2012) Zenglin Liao et al.   RESPIRATORY RESEARCH

Functional Metabolomics Reveals Novel Active Products in the DHA Metabolome

(2012) Masakazu Shinohara et al.   Frontiers in Immunology

Emerging Roles of Eosinophils and Eosinophil-Derived Lipid Mediators in the Resolution of Inflammation

(2012) Yosuke Isobe et al.   Frontiers in Immunology

Leukotriene B4/antimicrobial peptide LL-37 proinflammatory circuits are mediated by BLT1 and FPR2/ALX and are counterregulated by lipoxin A4 and resolvin E1

(2011) Min Wan et al.   FASEB JOURNAL

Pro-resolving actions and stereoselective biosynthesis of 18S E-series resolvins in human leukocytes and murine inflammation

(2011) Sungwhan F. Oh et al.   JOURNAL OF CLINICAL INVESTIGATION

HCV Peptide (C5A), an Amphipathic  -Helical Peptide of Hepatitis Virus C, Is an Activator of N-Formyl Peptide Receptor in Human Phagocytes

(2011) Q. Lin et al.   JOURNAL OF IMMUNOLOGY

Docosahexaenoic Acid-Derived Neuroprotectin D1 Induces Neuronal Survival via Secretase- and PPARγ-Mediated Mechanisms in Alzheimer's Disease Models

(2011) Yuhai Zhao et al.   PLoS One

The Human Serum Metabolome

(2011) Nikolaos Psychogios et al.   PLoS One

ChemR23 Dampens Lung Inflammation and Enhances Anti-viral Immunity in a Mouse Model of Acute Viral Pneumonia

(2011) Benjamin Bondue et al.   PLoS Pathogens

Effects of Oseltamivir Treatment on Duration of Clinical Illness and Viral Shedding and Household Transmission of Influenza Virus

(2010) Sophia Ng et al.   CLINICAL INFECTIOUS DISEASES

FPR2/ALX receptor expression and internalization are critical for lipoxin A4 and annexin-derived peptide-stimulated phagocytosis

(2010) Paola Maderna et al.   FASEB JOURNAL

Controlling Herpes Simplex Virus-Induced Ocular Inflammatory Lesions with the Lipid-Derived Mediator Resolvin E1

(2010) N. K. Rajasagi et al.   JOURNAL OF IMMUNOLOGY

Lethal Dissemination of H5N1 Influenza Virus Is Associated with Dysregulation of Inflammation and Lipoxin Signaling in a Mouse Model of Infection

(2010) C. Cilloniz et al.   JOURNAL OF VIROLOGY

Control of RSV-induced lung injury by alternatively activated macrophages is IL-4Rα-, TLR4- and IFN-β-dependent

(2010) K A Shirey et al.   Mucosal Immunology

Lovastatin decreases acute mucosal inflammation via 15-epi-lipoxin A4

(2010) A Planagumà et al.   Mucosal Immunology

Resolvin D1 binds human phagocytes with evidence for proresolving receptors

(2010) S. Krishnamoorthy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mouse ChemR23 Is Expressed in Dendritic Cell Subsets and Macrophages, and Mediates an Anti-Inflammatory Activity of Chemerin in a Lung Disease Model

(2009) S. Luangsay et al.   JOURNAL OF IMMUNOLOGY

Virus Entry via the Alternative Coreceptors CCR3 and FPRL1 Differs by Human Immunodeficiency Virus Type 1 Subtype

(2009) R. Nedellec et al.   JOURNAL OF VIROLOGY

Herpes Simplex

(2009) P. Chayavichitsilp et al.   PEDIATRICS IN REVIEW

Emerging Concepts in the Immunopathogenesis of AIDS

(2008) Daniel C. Douek et al.   Annual Review of Medicine

Resolvin E1 regulates interleukin 23, interferon-γ and lipoxin A4 to promote the resolution of allergic airway inflammation

(2008) Oliver Haworth et al.   NATURE IMMUNOLOGY

A formylpeptide receptor, FPRL1, acts as an efficient coreceptor for primary isolates of human immunodeficiency virus

(2008) Nobuaki Shimizu et al.   Retrovirology