Topoisomerase IIα poisoning and DNA double-strand breaking by chiral ruthenium(ii) complexes containing 2-furanyl-imidazo[4,5-f][1,10]phenanthroline derivatives

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Heterocyclic Anticancer Compounds: Recent Advances and the Paradigm Shift towards the Use of Nanomedicine’s Tool Box

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DNA Topoisomerases Are Required for Preinitiation Complex Assembly during GAL Gene Activation

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Dual inhibition of topoisomerases I and IIα by ruthenium(ii) complexes containing asymmetric tridentate ligands

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New Mechanistic and Functional Insights into DNA Topoisomerases

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Chiral ruthenium(ii) complexes with phenolic hydroxyl groups as dual poisons of topoisomerases I and IIα

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Dual topoisomerase I and II poisoning by chiral Ru(II) complexes containing 2-thiophenylimidazo[4,5-f][1,10]phenanthroline derivatives

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Drugging Topoisomerases: Lessons and Challenges

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The Structure of DNA-Bound Human Topoisomerase II Alpha: Conformational Mechanisms for Coordinating Inter-Subunit Interactions with DNA Cleavage

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Ruthenium complexes containing bis-benzimidazole derivatives as a new class of apoptosis inducers

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Structural Basis of Type II Topoisomerase Inhibition by the Anticancer Drug Etoposide

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Synthesis and in vitro evaluation of novel 1,2,4-triazine derivatives as neuroprotective agents

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DNA Topoisomerase II Enzymes as Molecular Targets for Cancer Chemotherapy

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Nuclear Permeable Ruthenium(II) β-Carboline Complexes Induce Autophagy To Antagonize Mitochondrial-Mediated Apoptosis

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DNA Topoisomerase I Inhibitors: Chemistry, Biology, and Interfacial Inhibition

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Synthesis and biological activity studies of furan derivatives

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Mechanism of Cellular Uptake of a Ruthenium Polypyridyl Complex†

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Synthesis, GC selective DNA binding and topoisomerase II inhibition activities of ruthenium(II) polypyridyl complex containing 11-aminopteridino[6,7-f][1,10]phenanthrolin-13(12H)-one

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