Translational control by eIF2α in neurons: Beyond the stress response
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Title
Translational control by eIF2α in neurons: Beyond the stress response
Authors
Keywords
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Journal
Cytoskeleton
Volume 73, Issue 10, Pages 551-565
Publisher
Wiley
Online
2016-03-20
DOI
10.1002/cm.21294
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Note: Only part of the references are listed.- Stress granules, P-bodies and cancer
- (2015) Paul Anderson et al. Biochimica et Biophysica Acta-Gene Regulatory Mechanisms
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- (2015) Y. Segev et al. JOURNAL OF NEUROSCIENCE
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- (2015) A. L. Kalinski et al. JOURNAL OF NEUROSCIENCE
- Guanabenz Treatment Accelerates Disease in a Mutant SOD1 Mouse Model of ALS
- (2015) Fernando G. Vieira et al. PLoS One
- Re-examination of Dietary Amino Acid Sensing Reveals a GCN2-Independent Mechanism
- (2015) David E. Leib et al. Cell Reports
- Specific Downregulation of Hippocampal ATF4 Reveals a Necessary Role in Synaptic Plasticity and Memory
- (2015) Silvia Pasini et al. Cell Reports
- Actin dynamics tune the integrated stress response by regulating eukaryotic initiation factor 2α dephosphorylation
- (2015) Joseph E Chambers et al. eLife
- Axonally Synthesized ATF4 Transmits a Neurodegenerative Signal across Brain Regions
- (2014) Jimena Baleriola et al. CELL
- eIF2 Dephosphorylation in Basolateral Amygdala Mediates Reconsolidation of Drug Memory
- (2014) M. Jian et al. JOURNAL OF NEUROSCIENCE
- Genetic or Pharmacological Reduction of PERK Enhances Cortical-Dependent Taste Learning
- (2014) H. Ounallah-Saad et al. JOURNAL OF NEUROSCIENCE
- ATF4: a Novel Potential Therapeutic Target for Alzheimer’s Disease
- (2014) Na Wei et al. MOLECULAR NEUROBIOLOGY
- Translational control of mGluR-dependent long-term depression and object-place learning by eIF2α
- (2014) Gonzalo Viana Di Prisco et al. NATURE NEUROSCIENCE
- Disturbance of endoplasmic reticulum proteostasis in neurodegenerative diseases
- (2014) Claudio Hetz et al. NATURE REVIEWS NEUROSCIENCE
- PERK mediates eIF2α phosphorylation responsible for BACE1 elevation, CREB dysfunction and neurodegeneration in a mouse model of Alzheimer's disease
- (2014) Latha Devi et al. NEUROBIOLOGY OF AGING
- Guanabenz, which enhances the unfolded protein response, ameliorates mutant SOD1-induced amyotrophic lateral sclerosis
- (2014) Lijun Wang et al. NEUROBIOLOGY OF DISEASE
- Axonal Transport of TDP-43 mRNA Granules Is Impaired by ALS-Causing Mutations
- (2014) Nael H. Alami et al. NEURON
- Guanabenz delays the onset of disease symptoms, extends lifespan, improves motor performance and attenuates motor neuron loss in the SOD1 G93A mouse model of amyotrophic lateral sclerosis
- (2014) H.-Q. Jiang et al. NEUROSCIENCE
- RNA Sequence Reveals Mouse Retinal Transcriptome Changes Early after Axonal Injury
- (2014) Masayuki Yasuda et al. PLoS One
- ER Stress-Induced eIF2-alpha Phosphorylation Underlies Sensitivity of Striatal Neurons to Pathogenic Huntingtin
- (2014) Julia Leitman et al. PLoS One
- Activating transcription factor 4 (ATF4) modulates post-synaptic development and dendritic spine morphology
- (2014) Jin Liu et al. Frontiers in Cellular Neuroscience
- Hypothalamic eIF2α Signaling Regulates Food Intake
- (2014) Anne-Catherine Maurin et al. Cell Reports
- Roles of eIF2α kinases in the pathogenesis of Alzheimer’s disease
- (2014) Masuo Ohno Frontiers in Molecular Neuroscience
- Protective neuronal induction of ATF5 in endoplasmic reticulum stress induced by status epilepticus
- (2013) Jesús F. Torres-Peraza et al. BRAIN
- Co-Opting the Unfolded Protein Response to Elicit Olfactory Receptor Feedback
- (2013) Ryan P. Dalton et al. CELL
- Stress granules in neurodegeneration - lessons learnt from TAR DNA binding protein of 43 kDa and fused in sarcoma
- (2013) Eva Bentmann et al. FEBS Journal
- Consolidation of object recognition memory requires HRI kinase-dependent phosphorylation of eIF2α in the hippocampus
- (2013) Gerard ILL-Raga et al. HIPPOCAMPUS
- An enhanced integrated stress response ameliorates mutant SOD1-induced ALS
- (2013) L. Wang et al. HUMAN MOLECULAR GENETICS
- IMPACT Is a Developmentally Regulated Protein in Neurons That Opposes the Eukaryotic Initiation Factor 2α Kinase GCN2 in the modulation of Neurite Outgrowth
- (2013) Martín Roffé et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Blocking the eIF2 Kinase (PKR) Enhances Positive and Negative Forms of Cortex-Dependent Taste Memory
- (2013) E. Stern et al. JOURNAL OF NEUROSCIENCE
- Therapeutic modulation of eIF2α phosphorylation rescues TDP-43 toxicity in amyotrophic lateral sclerosis disease models
- (2013) Hyung-Jun Kim et al. NATURE GENETICS
- Suppression of eIF2α kinases alleviates Alzheimer's disease–related plasticity and memory deficits
- (2013) Tao Ma et al. NATURE NEUROSCIENCE
- Restoring endoplasmic reticulum homeostasis improves functional recovery after spinal cord injury
- (2013) Sujata Saraswat Ohri et al. NEUROBIOLOGY OF DISEASE
- Functional Contribution of the Transcription Factor ATF4 to the Pathogenesis of Amyotrophic Lateral Sclerosis
- (2013) Soledad Matus et al. PLoS One
- ALS-Associated TDP-43 Induces Endoplasmic Reticulum Stress, Which Drives Cytoplasmic TDP-43 Accumulation and Stress Granule Formation
- (2013) Adam K. Walker et al. PLoS One
- Deletion of the eIF2α Kinase GCN2 Fails to Rescue the Memory Decline Associated with Alzheimer’s Disease
- (2013) Latha Devi et al. PLoS One
- GCN2 in the Brain Programs PPARγ2 and Triglyceride Storage in the Liver during Perinatal Development in Response to Maternal Dietary Fat
- (2013) Xu Xu et al. PLoS One
- A strategy to capture and characterize the synaptic transcriptome
- (2013) S. V. Puthanveettil et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Oral Treatment Targeting the Unfolded Protein Response Prevents Neurodegeneration and Clinical Disease in Prion-Infected Mice
- (2013) J. A. Moreno et al. Science Translational Medicine
- Gene Expression Regulation by Upstream Open Reading Frames and Human Disease
- (2013) Cristina Barbosa et al. PLoS Genetics
- Pharmacological brake-release of mRNA translation enhances cognitive memory
- (2013) Carmela Sidrauski et al. eLife
- Mechanisms that lessen benefits of β-secretase reduction in a mouse model of Alzheimer’s disease
- (2013) L Devi et al. Translational Psychiatry
- Oxidative stress increases BACE1 protein levels through activation of the PKR-eIF2α pathway
- (2012) François Mouton-Liger et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Pharmacological Inhibition of PKR in APPswePS1dE9 Mice Transiently Prevents Inflammation at 12 Months of Age but Increases Aβ42 Levels in the Late Stages of the Alzheimer’s Disease
- (2012) Julien Couturier et al. Current Alzheimer Research
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- (2012) E. Colla et al. JOURNAL OF NEUROSCIENCE
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- (2012) Benoit D Roussel et al. LANCET NEUROLOGY
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- (2012) A. G. Hinnebusch et al. Cold Spring Harbor Perspectives in Biology
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- (2012) V Valenzuela et al. Cell Death & Disease
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- (2011) Hae Young Lee et al. Developmental Neurobiology
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- (2011) Guangfu Li et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2011) Lakshmi Reddy Palam et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Local RNA Translation at the Synapse and in Disease
- (2011) L. Liu-Yesucevitz et al. JOURNAL OF NEUROSCIENCE
- The eIF2 kinase PERK and the integrated stress response facilitate activation of ATF6 during endoplasmic reticulum stress
- (2011) Brian F. Teske et al. MOLECULAR BIOLOGY OF THE CELL
- Resolving controversies on the path to Alzheimer's therapeutics
- (2011) Dennis J Selkoe NATURE MEDICINE
- De novo generation of prion strains
- (2011) David W. Colby et al. NATURE REVIEWS MICROBIOLOGY
- Clinical genetics of amyotrophic lateral sclerosis: what do we really know?
- (2011) Peter M. Andersen et al. Nature Reviews Neurology
- Unraveling regulation and new components of human P-bodies through a protein interaction framework and experimental validation
- (2011) D. Zheng et al. RNA
- Selective Inhibition of a Regulatory Subunit of Protein Phosphatase 1 Restores Proteostasis
- (2011) P. Tsaytler et al. SCIENCE
- Alzheimer's Disease: The Challenge of the Second Century
- (2011) D. M. Holtzman et al. Science Translational Medicine
- Prions
- (2011) D. W. Colby et al. Cold Spring Harbor Perspectives in Biology
- The unfolded protein response in familial amyotrophic lateral sclerosis
- (2010) L. Wang et al. HUMAN MOLECULAR GENETICS
- A Role for Huntington Disease Protein in Dendritic RNA Granules
- (2010) Jeffrey N. Savas et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- eIF2 Phosphorylation-Dependent Translation in CA1 Pyramidal Cells Impairs Hippocampal Memory Consolidation without Affecting General Translation
- (2010) Z. Jiang et al. JOURNAL OF NEUROSCIENCE
- The mechanism of eukaryotic translation initiation and principles of its regulation
- (2010) Richard J. Jackson et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Activation of eukaryotic initiation factor-2α-kinases in okadaic acid-treated neurons
- (2010) S.M. Kim et al. NEUROSCIENCE
- Alzheimer's Disease
- (2010) Henry W. Querfurth et al. NEW ENGLAND JOURNAL OF MEDICINE
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- (2010) J. Fah Sathirapongsasuti et al. NUCLEIC ACIDS RESEARCH
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- (2010) Latha Devi et al. PLoS One
- Prion protein interaction with stress-inducible protein 1 enhances neuronal protein synthesis via mTOR
- (2010) M. Roffe et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Rethinking ALS: The FUS about TDP-43
- (2009) Clotilde Lagier-Tourenne et al. CELL
- mRNA Localization: Gene Expression in the Spatial Dimension
- (2009) Kelsey C. Martin et al. CELL
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- (2009) Yun-Young Lee et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mammalian Staufen 1 is recruited to stress granules and impairs their assembly
- (2009) M. G. Thomas et al. JOURNAL OF CELL SCIENCE
- A role for motoneuron subtype–selective ER stress in disease manifestations of FALS mice
- (2009) Smita Saxena et al. NATURE NEUROSCIENCE
- RNA granules: post-transcriptional and epigenetic modulators of gene expression
- (2009) Paul Anderson et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Involvement of CHOP, an ER-stress apoptotic mediator, in both human sporadic ALS and ALS model mice
- (2009) Yasushi Ito et al. NEUROBIOLOGY OF DISEASE
- Translational Control of Long-Lasting Synaptic Plasticity and Memory
- (2009) Mauro Costa-Mattioli et al. NEURON
- Ppp1r15 gene knockout reveals an essential role for translation initiation factor 2 alpha (eIF2α) dephosphorylation in mammalian development
- (2009) Heather P. Harding et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Upstream open reading frames cause widespread reduction of protein expression and are polymorphic among humans
- (2009) S. E. Calvo et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Subcellular mRNA Localization in Animal Cells and Why It Matters
- (2009) C. E. Holt et al. SCIENCE
- Mutations in FUS, an RNA Processing Protein, Cause Familial Amyotrophic Lateral Sclerosis Type 6
- (2009) C. Vance et al. SCIENCE
- Mutations in the FUS/TLS Gene on Chromosome 16 Cause Familial Amyotrophic Lateral Sclerosis
- (2009) T. J. Kwiatkowski et al. SCIENCE
- Re-Expression of Transcription Factor ATF5 in Hepatocellular Carcinoma Induces G2-M Arrest
- (2008) J. W-M. Gho et al. CANCER RESEARCH
- Inhibition of endoplasmic reticulum stress counteracts neuronal cell death and protein aggregation caused by N-terminal mutant huntingtin proteins
- (2008) Sami Reijonen et al. EXPERIMENTAL CELL RESEARCH
- ALS-linked mutant SOD1 induces ER stress- and ASK1-dependent motor neuron death by targeting Derlin-1
- (2008) H. Nishitoh et al. GENES & DEVELOPMENT
- Phosphorylation of eIF2 DirectsATF5Translational Control in Response to Diverse Stress Conditions
- (2008) Donghui Zhou et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Deadenylation is prerequisite for P-body formation and mRNA decay in mammalian cells
- (2008) Dinghai Zheng et al. JOURNAL OF CELL BIOLOGY
- TDP-43, the signature protein of FTLD-U, is a neuronal activity-responsive factor
- (2008) I.-Fan Wang et al. JOURNAL OF NEUROCHEMISTRY
- The Control of mRNA Decapping and P-Body Formation
- (2008) Tobias M. Franks et al. MOLECULAR CELL
- A functional RNAi screen links O-GlcNAc modification of ribosomal proteins to stress granule and processing body assembly
- (2008) Takbum Ohn et al. NATURE CELL BIOLOGY
- Phosphorylation of the Translation Initiation Factor eIF2α Increases BACE1 Levels and Promotes Amyloidogenesis
- (2008) Tracy O'Connor et al. NEURON
- An upstream open reading frame within an IRES controls expression of a specific VEGF-A isoform
- (2008) Amandine Bastide et al. NUCLEIC ACIDS RESEARCH
- Antihypertensive Drug Guanabenz Is Active In Vivo against both Yeast and Mammalian Prions
- (2008) Déborah Tribouillard-Tanvier et al. PLoS One
- A Point Mutation in Translation Initiation Factor 2B Leads to a Continuous Hyper Stress State in Oligodendroglial-Derived Cells
- (2008) Liraz Kantor et al. PLoS One
- Huntington's disease protein contributes to RNA-mediated gene silencing through association with Argonaute and P bodies
- (2008) J. N. Savas et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Importin-mediated retrograde transport of CREB2 from distal processes to the nucleus in neurons
- (2008) K.-O. Lai et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Stress granules: the Tao of RNA triage
- (2008) Paul Anderson et al. TRENDS IN BIOCHEMICAL SCIENCES
- Superoxide dismutase 1 mutants related to amyotrophic lateral sclerosis induce endoplasmic stress in neuro2a cells
- (2007) Yeo Kyoung Oh et al. JOURNAL OF NEUROCHEMISTRY
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