Cartilage‐targeting ultrasmall lipid‐polymer hybrid nanoparticles for the prevention of cartilage degradation

Interplay between genetics and epigenetics in osteoarthritis

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Intra-articular targeting of nanomaterials for the treatment of osteoarthritis

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Gaps in appropriate use of treatment strategies in osteoarthritis

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Epidemiology of osteoarthritis

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Recent advances in intra-articular drug delivery systems for osteoarthritis therapy

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Noninvasive visualization of early osteoarthritic cartilage using targeted nanosomes in a destabilization of the medial meniscus mouse model

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Molecular transport in articular cartilage — what have we learned from the past 50 years?

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Activation of AMPK-SIRT3 Signaling is Chondroprotective by Preserving Mitochondrial DNA Integrity and Function

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Treatment of collagenase-induced osteoarthritis with a viral vector encoding TSG-6 results in ectopic bone formation

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Neutrophil membrane-coated nanoparticles inhibit synovial inflammation and alleviate joint damage in inflammatory arthritis

(2018) Qiangzhe Zhang et al.   Nature Nanotechnology

Intra-articular treatment options for knee osteoarthritis

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Cartilage-penetrating nanocarriers improve delivery and efficacy of growth factor treatment of osteoarthritis

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Cartilage-targeting dexamethasone prodrugs increase the efficacy of dexamethasone

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The role of metabolism in the pathogenesis of osteoarthritis

(2017) Ali Mobasheri et al.   Nature Reviews Rheumatology

Cartilage-targeting drug delivery: can electrostatic interactions help?

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Systemic pan-AMPK activator MK-8722 improves glucose homeostasis but induces cardiac hypertrophy

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Emerging role of metabolic signaling in synovial joint remodeling and osteoarthritis

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Ultra-small lipid–polymer hybrid nanoparticles for tumor-penetrating drug delivery

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Ageing and the pathogenesis of osteoarthritis

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High LDL levels lead to increased synovial inflammation and accelerated ectopic bone formation during experimental osteoarthritis

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Charge based intra-cartilage delivery of single dose dexamethasone using Avidin nano-carriers suppresses cytokine-induced catabolism long term

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Charge-Controlled Nanoprecipitation as a Modular Approach to Ultrasmall Polymer Nanocarriers: Making Bright and Stable Nanoparticles

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Prophylactic treatment with S100A9 inhibitor paquinimod reduces pathology in experimental collagenase-induced osteoarthritis

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Intra-articular delivery of anti-Hif-2α siRNA by chondrocyte-homing nanoparticles to prevent cartilage degeneration in arthritic mice

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PEG shielded MMP sensitive CPPs for efficient and tumor specific gene delivery in vivo

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On the predictive utility of animal models of osteoarthritis

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Mitochondrial Biogenesis Is Impaired in Osteoarthritis Chondrocytes but Reversible via Peroxisome Proliferator-Activated Receptor γ Coactivator 1α

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Mouse models of osteoarthritis: modelling risk factors and assessing outcomes

(2014) Hang Fang et al.   Nature Reviews Rheumatology

Animal Models of Osteoarthritis: Challenges of Model Selection and Analysis

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Epidemiology and burden of osteoarthritis

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Large-Scale Synthesis of Lipid–Polymer Hybrid Nanoparticles Using a Multi-Inlet Vortex Reactor

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Higuchi equation: Derivation, applications, use and misuse

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Biofunctional polymer nanoparticles for intra-articular targeting and retention in cartilage

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