Activation of Ca2+-sensing receptor as a protective pathway to reduce Cadmium-induced cytotoxicity in renal proximal tubular cells

Parkin deficiency exacerbate ethanol-induced dopaminergic neurodegeneration by P38 pathway dependent inhibition of autophagy and mitochondrial function

(2017) Chul Ju Hwang et al.   Redox Biology

Importance of ROS-mediated autophagy in determining apoptotic cell death induced by physapubescin B

(2017) Jian Xu et al.   Redox Biology

The calcium-sensing receptor and the hallmarks of cancer

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The ROCK/GGTase Pathway Are Essential to the Proliferation and Differentiation of Neural Stem Cells Mediated by Simvastatin

(2016) Chan Zhang et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

The role of autophagy during cadmium induced apoptosis in rat renal tubular epithelial cells

(2016) G. Liu et al.   TOXICOLOGY LETTERS

Pleiotropic roles of Ca+2/calmodulin-dependent pathways in regulating cadmium-induced toxicity in human osteoblast-like cell lines

(2016) Thao T. Ha et al.   TOXICOLOGY LETTERS

Expression of basolateral organic anion and cation transporters in experimental cadmium nephrotoxicity in rat kidney

(2015) Marija Ljubojević et al.   ARCHIVES OF TOXICOLOGY

Cadmium Induced Apoptosis in MG63 Cells by Increasing ROS, Activation of p38 MAPK and Inhibition of ERK 1/2 Pathways

(2015) Kong-He Hu et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

2D-DIGE and MALDI TOF/TOF MS analysis reveal that small GTPase signaling pathways may play an important role in cadmium-induced colon cell malignant transformation

(2015) Jian Lu et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Calcium Homeostasis Disruption - a Bridge Connecting Cadmium-Induced Apoptosis, Autophagy and Tumorigenesis

(2015) Xuehai Zhou et al.   Oncology Research and Treatment

Oxidative stress and autophagy: Crucial modulators of kidney injury

(2015) Angara Sureshbabu et al.   Redox Biology

Interplay between ROS and autophagy in cancer cells, from tumor initiation to cancer therapy

(2015) Laura Poillet-Perez et al.   Redox Biology

Calcium and ROS: A mutual interplay

(2015) Agnes Görlach et al.   Redox Biology

Activation of gill Ca2+-sensing receptor as a protective pathway to reduce Ca2+-induced cytotoxicity

(2014) J. Gu et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Involvement of p38 in signal switching from autophagy to apoptosis via the PERK/eIF2α/ATF4 axis in selenite-treated NB4 cells

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Phosphorylation of FOXO3a by PI3K/Akt pathway in HK-2 renal proximal tubular epithelial cells exposed to cadmium

(2013) Kota Fujiki et al.   ARCHIVES OF TOXICOLOGY

Cadmium and cellular signaling cascades: interactions between cell death and survival pathways

(2013) Frank Thévenod et al.   ARCHIVES OF TOXICOLOGY

Induction of cytoprotective autophagy in PC-12 cells by cadmium

(2013) Qiwen Wang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

New insights in regulation of calcium homeostasis

(2013) Arnold Felsenfeld et al.   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

Cadmium-Induced Apoptosis in Primary Rat Cerebral Cortical Neurons Culture Is Mediated by a Calcium Signaling Pathway

(2013) Yan Yuan et al.   PLoS One

Calcium–calmodulin signaling elicits mitochondrial dysfunction and the release of cytochrome c during cadmium-induced apoptosis in primary osteoblasts

(2013) Wei Liu et al.   TOXICOLOGY LETTERS

Inhibition of autophagy promotes CYP2E1-dependent toxicity in HepG2 cells via elevated oxidative stress, mitochondria dysfunction and activation of p38 and JNK MAPK

(2013) Defeng Wu et al.   Redox Biology

Autophagy and mitophagy in cellular damage control

(2013) Jianhua Zhang   Redox Biology

Calcium sensing receptor signalling in physiology and cancer

(2012) Sarah C. Brennan et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Phosphorylation of Atg5 by the Gadd45β–MEKK4-p38 pathway inhibits autophagy

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Effects of salubrinal on cadmium-induced apoptosis in HK-2 human renal proximal tubular cells

(2011) Yuta Komoike et al.   ARCHIVES OF TOXICOLOGY

CaMKII is involved in cadmium activation of MAPK and mTOR pathways leading to neuronal cell death

(2011) Sujuan Chen et al.   JOURNAL OF NEUROCHEMISTRY

Calcium Signaling Is Involved in Cadmium-Induced Neuronal Apoptosis via Induction of Reactive Oxygen Species and Activation of MAPK/mTOR Network

(2011) Baoshan Xu et al.   PLoS One

Cadmium induces autophagy through ROS-dependent activation of the LKB1–AMPK signaling in skin epidermal cells

(2011) Young-Ok Son et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Multiple roles of cadmium in cell death and survival

(2010) Douglas M. Templeton et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Cadmium induction of reactive oxygen species activates the mTOR pathway, leading to neuronal cell death

(2010) Long Chen et al.   FREE RADICAL BIOLOGY AND MEDICINE

Autophagy involvement in cadmium resistance through induction of multidrug resistance-associated protein and counterbalance of endoplasmic reticulum stress WI38 lung epithelial fibroblast cells

(2010) Sung-Chul Lim et al.   TOXICOLOGY

The cadmium-induced death of mesangial cells results in nephrotoxicity

(2009) Liang-Yo Yang et al.   Autophagy

Cadmium-induced Cytosolic Ca2+ Elevation and Subsequent Apoptosis in Renal Tubular Cells

(2009) Jeng-Hsien Yeh et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

ERK and cell death: cadmium toxicity, sustained ERK activation and cell death

(2009) Patrick Martin et al.   FEBS Journal

Cd-induced apoptosis was mediated by the release of Ca2+ from intracellular Ca storage

(2009) Zhuoyi Xie et al.   TOXICOLOGY LETTERS

Role of Oxidative Stress, Apoptosis, and Intracellular Homeostasis in Primary Cultures of Rat Proximal Tubular Cells Exposed to Cadmium

(2008) Lin Wang et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Cadmium-induced autophagy and apoptosis are mediated by a calcium signaling pathway

(2008) S. H. Wang et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Cadmium activates the mitogen-activated protein kinase (MAPK) pathway via induction of reactive oxygen species and inhibition of protein phosphatases 2A and 5

(2008) Long Chen et al.   FREE RADICAL BIOLOGY AND MEDICINE

Gain-of-function haplotype in the epithelial calcium channel TRPV6 is a risk factor for renal calcium stone formation

(2008) Yoshiro Suzuki et al.   HUMAN MOLECULAR GENETICS

MAPK and mTOR pathways are involved in cadmium-induced neuronal apoptosis

(2008) Long Chen et al.   JOURNAL OF NEUROCHEMISTRY

Calcium, mitochondria and apoptosis studied by fluorescence measurements

(2008) Soumya Sinha Roy et al.   METHODS

Mechanisms and Regulation of Epithelial Ca2+ Absorption in Health and Disease

(2007) Yoshiro Suzuki et al.   Annual Review of Physiology

Endoplasmic reticulum stress and alteration in calcium homeostasis are involved in cadmium-induced apoptosis

(2007) Marta Biagioli et al.   CELL CALCIUM