The transcription factor E2A activates multiple enhancers that drive Rag expression in developing T and B cells
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
The transcription factor E2A activates multiple enhancers that drive Rag expression in developing T and B cells
Authors
Keywords
-
Journal
Science Immunology
Volume 5, Issue 51, Pages eabb1455
Publisher
American Association for the Advancement of Science (AAAS)
Online
2020-09-05
DOI
10.1126/sciimmunol.abb1455
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Upon microbial challenge, human neutrophils undergo rapid changes in nuclear architecture and chromatin folding to orchestrate an immediate inflammatory gene program
- (2020) Matthew Denholtz et al. GENES & DEVELOPMENT
- Helix–loop–helix proteins and the advent of cellular diversity: 30 years of discovery
- (2019) Cornelis Murre GENES & DEVELOPMENT
- Transcription factors and 3D genome conformation in cell-fate decisions
- (2019) Ralph Stadhouders et al. NATURE
- Programming for T-lymphocyte fates: modularity and mechanisms
- (2019) Ellen V. Rothenberg GENES & DEVELOPMENT
- Mechanisms of Interplay between Transcription Factors and the 3D Genome
- (2019) Seungsoo Kim et al. MOLECULAR CELL
- Analysis of Genetically Diverse Macrophages Reveals Local and Domain-wide Mechanisms that Control Transcription Factor Binding and Function
- (2018) Verena M. Link et al. CELL
- The Energetics and Physiological Impact of Cohesin Extrusion
- (2018) Laura Vian et al. CELL
- Transformation of Accessible Chromatin and 3D Nucleome Underlies Lineage Commitment of Early T Cells
- (2018) Gangqing Hu et al. IMMUNITY
- Lineage-Determining Transcription Factor TCF-1 Initiates the Epigenetic Identity of T Cells
- (2018) John L. Johnson et al. IMMUNITY
- Transcription Elongation Can Affect Genome 3D Structure
- (2018) Sven Heinz et al. CELL
- Transcription Factors Activate Genes through the Phase-Separation Capacity of Their Activation Domains
- (2018) Ann Boija et al. CELL
- Hierarchical assembly and disassembly of a transcriptionally active RAG locus in CD4+CD8+ thymocytes
- (2018) Abani Kanta Naik et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Bcl11b sets pro-T cell fate by site-specific cofactor recruitment and by repressing Id2 and Zbtb16
- (2018) Hiroyuki Hosokawa et al. NATURE IMMUNOLOGY
- New insights into the evolutionary origins of the recombination-activating gene proteins and V(D)J recombination
- (2017) Lina Marcela Carmona et al. FEBS Journal
- The E-Id Protein Axis Specifies Adaptive Lymphoid Cell Identity and Suppresses Thymic Innate Lymphoid Cell Development
- (2017) Masaki Miyazaki et al. IMMUNITY
- Guidance of regulatory T cell development by Satb1-dependent super-enhancer establishment
- (2016) Yohko Kitagawa et al. NATURE IMMUNOLOGY
- Tet2 and Tet3 cooperate with B-lineage transcription factors to regulate DNA modification and chromatin accessibility
- (2016) Chan-Wang Lio et al. eLife
- The E–Id protein axis modulates the activities of the PI3K–AKT–mTORC1–Hif1a and c-myc/p19Arf pathways to suppress innate variant TFHcell development, thymocyte expansion, and lymphomagenesis
- (2015) Masaki Miyazaki et al. GENES & DEVELOPMENT
- Spatial enhancer clustering and regulation of enhancer-proximal genes by cohesin
- (2015) Elizabeth Ing-Simmons et al. GENOME RESEARCH
- An anti-silencer– and SATB1-dependent chromatin hub regulatesRag1andRag2gene expression during thymocyte development
- (2015) Bingtao Hao et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Chromatin architecture reorganization during stem cell differentiation
- (2015) Jesse R. Dixon et al. NATURE
- New roles for DNA cytosine modification, eRNA, anchors, and superanchors in developing B cell progenitors
- (2015) Christopher Benner et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- CRISPRdirect: software for designing CRISPR/Cas guide RNA with reduced off-target sites
- (2014) Yuki Naito et al. BIOINFORMATICS
- A 3D Map of the Human Genome at Kilobase Resolution Reveals Principles of Chromatin Looping
- (2014) Suhas S.P. Rao et al. CELL
- Master Transcription Factors and Mediator Establish Super-Enhancers at Key Cell Identity Genes
- (2013) Warren A. Whyte et al. CELL
- Super-Enhancers in the Control of Cell Identity and Disease
- (2013) Denes Hnisz et al. CELL
- Interactome Maps of Mouse Gene Regulatory Domains Reveal Basic Principles of Transcriptional Regulation
- (2013) Kyong-Rim Kieffer-Kwon et al. CELL
- Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome position
- (2013) Jason D Buenrostro et al. NATURE METHODS
- Global changes in the nuclear positioning of genes and intra- and interdomain genomic interactions that orchestrate B cell fate
- (2012) Yin C Lin et al. NATURE IMMUNOLOGY
- Fast gapped-read alignment with Bowtie 2
- (2012) Ben Langmead et al. NATURE METHODS
- The opposing roles of the transcription factor E2A and its antagonist Id3 that orchestrate and enforce the naive fate of T cells
- (2011) Masaki Miyazaki et al. NATURE IMMUNOLOGY
- Transcription control of early B cell differentiation
- (2010) Elizabeth M Mandel et al. CURRENT OPINION IN IMMUNOLOGY
- Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities
- (2010) Sven Heinz et al. MOLECULAR CELL
- A global network of transcription factors, involving E2A, EBF1 and Foxo1, that orchestrates B cell fate
- (2010) Yin C Lin et al. NATURE IMMUNOLOGY
- BLAST+: architecture and applications
- (2009) Christiam Camacho et al. BMC BIOINFORMATICS
- Mechanisms controlling expression of the RAG locus during lymphocyte development
- (2009) Tracy C Kuo et al. CURRENT OPINION IN IMMUNOLOGY
- Mechanics of T cell receptor gene rearrangement
- (2009) Michael S Krangel CURRENT OPINION IN IMMUNOLOGY
- Circos: An information aesthetic for comparative genomics
- (2009) M. Krzywinski et al. GENOME RESEARCH
- MEME SUITE: tools for motif discovery and searching
- (2009) T. L. Bailey et al. NUCLEIC ACIDS RESEARCH
- Comprehensive Mapping of Long-Range Interactions Reveals Folding Principles of the Human Genome
- (2009) E. Lieberman-Aiden et al. SCIENCE
- E2A Proteins Promote Development of Lymphoid-Primed Multipotent Progenitors
- (2008) Sheila Dias et al. IMMUNITY
- NWC, a new gene withinRAGlocus: could it keep GOD under control?
- (2008) P. Kisielow et al. International Journal of Immunogenetics
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now