The APMAP interactome reveals new modulators of APP processing and beta-amyloid production that are altered in Alzheimer’s disease

Why do trials for Alzheimer’s disease drugs keep failing? A discontinued drug perspective for 2010-2015

(2017) Dev Mehta et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Pathogenic PS1 phosphorylation at Ser367

(2017) Masato Maesako et al.   eLife

Sex differences between APPswePS1dE9 mice in A-beta accumulation and pancreatic islet function during the development of Alzheimer’s disease

(2016) Xin Li et al.   LABORATORY ANIMALS

The Perseus computational platform for comprehensive analysis of (prote)omics data

(2016) Stefka Tyanova et al.   NATURE METHODS

Amyloid precursor protein interaction network in human testis: sentinel proteins for male reproduction

(2015) Joana Vieira Silva et al.   BMC BIOINFORMATICS

Expression, function, and regulation of the testis-enriched heat shock HSPA2 gene in rodents and humans

(2014) Dorota Scieglinska et al.   CELL STRESS & CHAPERONES

Amyloid precursor protein and neural development

(2014) M. Nicolas et al.   DEVELOPMENT

The adipocyte differentiation protein APMAP is an endogenous suppressor of Aβ production in the brain

(2014) Sebastien Mosser et al.   HUMAN MOLECULAR GENETICS

Clusterin facilitates stress-induced lipidation of LC3 and autophagosome biogenesis to enhance cancer cell survival

(2014) Fan Zhang et al.   Nature Communications

Amyloid Beta A4 Precursor Protein-binding Family B Member 1 (FE65) Interactomics Revealed Synaptic Vesicle Glycoprotein 2A (SV2A) and Sarcoplasmic/Endoplasmic Reticulum Calcium ATPase 2 (SERCA2) as New Binding Proteins in the Human Brain

(2013) Fabian M. Nensa et al.   MOLECULAR & CELLULAR PROTEOMICS

The toxic Aβ oligomer and Alzheimer's disease: an emperor in need of clothes

(2012) Iryna Benilova et al.   NATURE NEUROSCIENCE

Optical controlling reveals time-dependent roles for adult-born dentate granule cells

(2012) Yan Gu et al.   NATURE NEUROSCIENCE

Adipogenesis

(2012) K. Sarjeant et al.   Cold Spring Harbor Perspectives in Biology

Hsp70.1 and related lysosomal factors for necrotic neuronal death

(2011) Tetsumori Yamashima   JOURNAL OF NEUROCHEMISTRY

Genetics: Finding risk factors

(2011) Michael Eisenstein   NATURE

The amyloid cascade hypothesis for Alzheimer's disease: an appraisal for the development of therapeutics

(2011) Eric Karran et al.   NATURE REVIEWS DRUG DISCOVERY

Connecting Hsp70, sphingolipid metabolism and lysosomal stability

(2010) Nikolaj H.T. Petersen et al.   CELL CYCLE

New neurons and new memories: how does adult hippocampal neurogenesis affect learning and memory?

(2010) Wei Deng et al.   NATURE REVIEWS NEUROSCIENCE

Analysis of the γ-secretase interactome and validation of its association with tetraspanin-enriched microdomains

(2009) Tomoko Wakabayashi et al.   NATURE CELL BIOLOGY

Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease

(2009) Jean-Charles Lambert et al.   NATURE GENETICS

Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

(2009) Denise Harold et al.   NATURE GENETICS

Are DBA/2 mice associated with schizophrenia-like endophenotypes? A behavioural contrast with C57BL/6 mice

(2009) Philipp Singer et al.   PSYCHOPHARMACOLOGY

Localization and characterization of the novel protein encoded by C20orf3

(2008) Aysegul Ilhan et al.   BIOCHEMICAL JOURNAL

Cell autonomous function of nogo and reticulons: The emerging story at the endoplasmic reticulum

(2008) Felicia Yu Hsuan Teng et al.   JOURNAL OF CELLULAR PHYSIOLOGY

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

(2008) Jürgen Cox et al.   NATURE BIOTECHNOLOGY