Explorative Combined Lipid and Transcriptomic Profiling of Substantia Nigra and Putamen in Parkinson’s Disease

The Role of Lipids in Parkinson’s Disease

(2019) Helena Xicoy et al.   Cells

A Computational Model of Loss of Dopaminergic Cells in Parkinson's Disease Due to Glutamate-Induced Excitotoxicity

(2019) Vignayanandam Ravindernath Muddapu et al.   Frontiers in Neural Circuits

The Parkinson-associated human P5B-ATPase ATP13A2 modifies lipid homeostasis

(2019) Alejandra Lucía Marcos et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

The role of lipids in α-synuclein misfolding and neurotoxicity

(2019) Cathryn L Ugalde et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

g:Profiler: a web server for functional enrichment analysis and conversions of gene lists (2019 update)

(2019) Uku Raudvere et al.   NUCLEIC ACIDS RESEARCH

Mice Lacking Brain-Derived Serotonin Have Altered Swallowing Function

(2019) Megan M. Haney et al.   OTOLARYNGOLOGY-HEAD AND NECK SURGERY

A Comprehensive Functional Characterization of Escherichia coli Lipid Genes

(2019) Aike Jeucken et al.   Cell Reports

Ceramides in Parkinson’s Disease: From Recent Evidence to New Hypotheses

(2019) Nicoletta Plotegher et al.   Frontiers in Neuroscience

Metabolome-based signature of disease pathology in MS

(2019) S.L. Andersen et al.   Multiple Sclerosis and Related Disorders

Lipid Analysis of the 6-Hydroxydopamine-Treated SH-SY5Y Cell Model for Parkinson’s Disease

(2019) Helena Xicoy et al.   MOLECULAR NEUROBIOLOGY

A systems biology approach towards the identification of candidate therapeutic genes and potential biomarkers for Parkinson’s disease

(2019) Meena Kishore Sakharkar et al.   PLoS One

Impact of estrogens and estrogen receptor-α in brain lipid metabolism

(2018) Eugenia Morselli et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Sex-Related Abnormalities in Substantia Nigra Lipids in Parkinson’s Disease

(2018) T. N. Seyfried et al.   ASN Neuro

Levels of α- and β-synuclein regulate cellular susceptibility to toxicity from α-synuclein oligomers

(2018) Dafina M. Angelova et al.   FASEB JOURNAL

Neurodegenerative diseases have genetic hallmarks of autoinflammatory disease

(2018) Robert I Richards et al.   HUMAN MOLECULAR GENETICS

Whole-Exome Sequencing in Searching for New Variants Associated With the Development of Parkinson’s Disease

(2018) Marina V. Shulskaya et al.   Frontiers in Aging Neuroscience

The P2X7 Receptor in Inflammatory Diseases: Angel or Demon?

(2018) Luiz E. B. Savio et al.   Frontiers in Pharmacology

The genetic landscape of Parkinson's disease

(2018) A. Lunati et al.   REVUE NEUROLOGIQUE

STRING v11: protein–protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets

(2018) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

A review of genome-wide transcriptomics studies in Parkinson's disease

(2017) Genevie Borrageiro et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

The relevance of gender in Parkinson’s disease: a review

(2017) Marina Picillo et al.   JOURNAL OF NEUROLOGY

Association between gene polymorphism and depression in Parkinson's disease: A case-control study

(2017) Jinhua Zheng et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Subcellular compartmentalisation of copper, iron, manganese, and zinc in the Parkinson's disease brain

(2017) Sian Genoud et al.   Metallomics

Salmon provides fast and bias-aware quantification of transcript expression

(2017) Rob Patro et al.   NATURE METHODS

HMDB 4.0: the human metabolome database for 2018

(2017) David S Wishart et al.   NUCLEIC ACIDS RESEARCH

Current understanding of the molecular mechanisms in Parkinson's disease: Targets for potential treatments

(2017) Panchanan Maiti et al.   Translational Neurodegeneration

Lipidomic profiling of tryptophan hydroxylase 2 knockout mice reveals novel lipid biomarkers associated with serotonin deficiency

(2016) Rui Weng et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

LRRK2 deficiency impacts ceramide metabolism in brain

(2016) Ruggero Ferrazza et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Ataxin-2 (Atxn2)-Knock-Out Mice Show Branched Chain Amino Acids and Fatty Acids Pathway Alterations

(2016) David Meierhofer et al.   MOLECULAR & CELLULAR PROTEOMICS

Genetic Variants of Microtubule Actin Cross-linking Factor 1 (MACF1) Confer Risk for Parkinson’s Disease

(2016) Xin Wang et al.   MOLECULAR NEUROBIOLOGY

Systems genetics identifies Hp1bp3 as a novel modulator of cognitive aging

(2016) Sarah M. Neuner et al.   NEUROBIOLOGY OF AGING

Tryptophan hydroxylase type 2 variants modulate severity and outcome of addictive behaviors in Parkinson's disease

(2016) Roberto Cilia et al.   PARKINSONISM & RELATED DISORDERS

Ret is essential to mediate GDNF’s neuroprotective and neuroregenerative effect in a Parkinson disease mouse model

(2016) Anja Drinkut et al.   Cell Death & Disease

The harmonizome: a collection of processed datasets gathered to serve and mine knowledge about genes and proteins

(2016) Andrew D. Rouillard et al.   Database-The Journal of Biological Databases and Curation

Sexually dimorphic brain fatty acid composition in low and high fat diet-fed mice

(2016) Carlos Rodriguez-Navas et al.   Molecular Metabolism

Meta-Analysis of Parkinson's Disease Transcriptome Data Using TRAM Software: Whole Substantia Nigra Tissue and Single Dopamine Neuron Differential Gene Expression

(2016) Elisa Mariani et al.   PLoS One

Depression and Synaptic Zinc Regulation in Alzheimer Disease, Dementia with Lewy Bodies, and Parkinson Disease Dementia

(2015) David R. Whitfield et al.   AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY

Serotonin in Parkinson's disease

(2015) Marios Politis et al.   BEHAVIOURAL BRAIN RESEARCH

Loss ofPLA2G6leads to elevated mitochondrial lipid peroxidation and mitochondrial dysfunction

(2015) Kerri J. Kinghorn et al.   BRAIN

Expanding Roles for Lipid Droplets

(2015) Michael A. Welte   CURRENT BIOLOGY

GDNF-Ret signaling in midbrain dopaminergic neurons and its implication for Parkinson disease

(2015) Edgar R. Kramer et al.   FEBS LETTERS

Pathways to Parkinsonism Redux: convergent pathobiological mechanisms in genetics of Parkinson's disease

(2015) Ravindran Kumaran et al.   HUMAN MOLECULAR GENETICS

No evidence for substrate accumulation in Parkinson brains withGBAmutations

(2015) Matthew E. Gegg et al.   MOVEMENT DISORDERS

Gene-Wise Association of Variants in Four Lysosomal Storage Disorder Genes in Neuropathologically Confirmed Lewy Body Disease

(2015) Lorraine N. Clark et al.   PLoS One

SREBF1links lipogenesis to mitophagy and sporadic Parkinson disease

(2014) Rachael M Ivatt et al.   Autophagy

Mesencephalic dopaminergic neurons express a repertoire of olfactory receptors and respond to odorant-like molecules

(2014) Alice Grison et al.   BMC GENOMICS

Potential roles of PINK1 for increased PGC-1α-mediated mitochondrial fatty acid oxidation and their associations with Alzheimer disease and diabetes

(2014) Joungil Choi et al.   MITOCHONDRION

Lipid landscapes and pipelines in membrane homeostasis

(2014) Joost C.M. Holthuis et al.   NATURE

Assessment of ZnT3 and PSD95 protein levels in Lewy body dementias and Alzheimer's disease: association with cognitive impairment

(2014) David R. Whitfield et al.   NEUROBIOLOGY OF AGING

Comparison of RNA-Seq and Microarray in Transcriptome Profiling of Activated T Cells

(2014) Shanrong Zhao et al.   PLoS One

Systems-Based Analyses of Brain Regions Functionally Impacted in Parkinson's Disease Reveals Underlying Causal Mechanisms

(2014) Brigit E. Riley et al.   PLoS One

Parkinson disease: from pathology to molecular disease mechanisms

(2013) David T. Dexter et al.   FREE RADICAL BIOLOGY AND MEDICINE

Selective reduction of bis(monoacylglycero)phosphate ameliorates the storage burden in a THP-1 macrophage model of Gaucher disease

(2013) Leanne K. Hein et al.   JOURNAL OF LIPID RESEARCH

Functional Genomics Reveals Dysregulation of Cortical Olfactory Receptors in Parkinson Disease: Novel Putative Chemoreceptors in the Human Brain

(2013) Paula Garcia-Esparcia et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

An Approach to Glycobiology from Glycolipidomics: Ganglioside Molecular Scanning in the Brains of Patients with Alzheimer^|^#8217;s Disease by TLC-Blot/Matrix Assisted Laser Desorption/Ionization-Time of Flight MS

(2012) Takao Taki   BIOLOGICAL & PHARMACEUTICAL BULLETIN

It’s a Lipid’s World: Bioactive Lipid Metabolism and Signaling in Neural Stem Cell Differentiation

(2012) Erhard Bieberich   NEUROCHEMICAL RESEARCH

Mitochondrial Inhibitor Models of Huntington’s Disease and Parkinson’s Disease Induce Zinc Accumulation and Are Attenuated by Inhibition of Zinc Neurotoxicity in vitro or in vivo

(2012) Christian T. Sheline et al.   Neurodegenerative Diseases

NCBI GEO: archive for functional genomics data sets—update

(2012) Tanya Barrett et al.   NUCLEIC ACIDS RESEARCH

clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters

(2012) Guangchuang Yu et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

Diagnosis of Parkinson's Disease Based on Disease-Specific Autoantibody Profiles in Human Sera

(2012) Min Han et al.   PLoS One

Transcriptional Activation of Low-Density Lipoprotein Receptor Gene by DJ-1 and Effect of DJ-1 on Cholesterol Homeostasis

(2012) Shiori Yamaguchi et al.   PLoS One

Progression of motor symptoms in Parkinson’s disease

(2012) Ruiping Xia et al.   Neuroscience Bulletin

Effects of Oestradiol on Brain Lipid Class and Fatty Acid Composition: Comparison Between Pregnant and Ovariectomised Oestradiol-Treated Rats

(2011) N. Fabelo et al.   JOURNAL OF NEUROENDOCRINOLOGY

Lipid Pathway Alterations in Parkinson's Disease Primary Visual Cortex

(2011) Danni Cheng et al.   PLoS One

ROAST: rotation gene set tests for complex microarray experiments

(2010) Di Wu et al.   BIOINFORMATICS

The risk of Parkinson’s disease in type 1 Gaucher disease

(2010) Gilberto Bultron et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Gender differences in Parkinson's disease: Clinical characteristics and cognition

(2010) Ivy N. Miller et al.   MOVEMENT DISORDERS

Lipolysis – A highly regulated multi-enzyme complex mediates the catabolism of cellular fat stores

(2010) Achim Lass et al.   PROGRESS IN LIPID RESEARCH

Differential expression analysis for sequence count data

(2010) Simon Anders et al.   GENOME BIOLOGY

Protein Misfolding and Aggregation in Parkinson's Disease

(2009) Jeanne M.M. Tan et al.   ANTIOXIDANTS & REDOX SIGNALING

Essential role of KLF5 transcription factor in cell proliferation and differentiation and its implications for human diseases

(2009) Jin-Tang Dong et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Evidence for potential functionality of nuclearly-encoded humanin isoforms

(2009) Marek Bodzioch et al.   GENOMICS

Non-motor symptoms of Parkinson's disease: dopaminergic pathophysiology and treatment

(2009) K Ray Chaudhuri et al.   LANCET NEUROLOGY

Neuroinflammation in Parkinson's disease: Its role in neuronal death and implications for therapeutic intervention

(2009) Malú G. Tansey et al.   NEUROBIOLOGY OF DISEASE

Environmental toxins and Parkinson's disease: what have we learned from pesticide-induced animal models?

(2009) Francesca Cicchetti et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

AmiGO: online access to ontology and annotation data

(2008) Seth Carbon et al.   BIOINFORMATICS

Update of the LIPID MAPS comprehensive classification system for lipids

(2008) Eoin Fahy et al.   JOURNAL OF LIPID RESEARCH

Integration of metabolism and inflammation by lipid-activated nuclear receptors

(2008) Steven J. Bensinger et al.   NATURE