Revisiting the Concept of Stress in the Prognosis of Solid Tumors: A Role for Stress Granules Proteins?

UBAP2L Forms Distinct Cores that Act in Nucleating Stress Granules Upstream of G3BP1

(2020) Luca Cirillo et al.   CURRENT BIOLOGY

G3BP1-linked mRNA partitioning supports selective protein synthesis in response to oxidative stress

(2020) Syam Prakash Somasekharan et al.   NUCLEIC ACIDS RESEARCH

Translational control of breast cancer plasticity

(2020) Michael Jewer et al.   Nature Communications

Translational Repression of G3BP in Cancer and Germ Cells Suppresses Stress Granules and Enhances Stress Tolerance

(2020) Anna K. Lee et al.   MOLECULAR CELL

Resistance to neoadjuvant chemotherapy in triple-negative breast cancer mediated by a reversible drug-tolerant state

(2019) Gloria V. Echeverria et al.   Science Translational Medicine

Role of caprin‑1 in carcinogenesis (Review)

(2019) Zhuo‑Shun Yang et al.   Oncology Letters

Emerging Evidence of Translational Control by AU-Rich Element-Binding Proteins

(2019) Hiroshi Otsuka et al.   Frontiers in Genetics

G3BP1 activates the TGF-β/Smad signaling pathway to promote gastric cancer

(2019) Rui Xiong et al.   OncoTargets and Therapy

Modeling of Cisplatin-Induced Signaling Dynamics in Triple-Negative Breast Cancer Cells Reveals Mediators of Sensitivity

(2019) Anne Margriet Heijink et al.   Cell Reports

Elevated expression of G3BP1 associates with YB1 and p‐AKT and predicts poor prognosis in nonsmall cell lung cancer patients after surgical resection

(2019) Hongmei Zheng et al.   Cancer Medicine

G3BP1 Depletion Increases Radiosensitisation by Inducing Oxidative Stress in Response to DNA Damage

(2019) EUGENE CHO et al.   ANTICANCER RESEARCH

eIF4A supports an oncogenic translation program in pancreatic ductal adenocarcinoma

(2019) Karina Chan et al.   Nature Communications

Drug-induced Stress Granule Formation Protects Sensory Hair Cells in Mouse Cochlear Explants During Ototoxicity

(2019) Ana Cláudia Gonçalves et al.   Scientific Reports

Clinical Significance of Ubiquitin-associated Protein 2-like in Patients With Uterine Cervical Cancer

(2019) KOSUKE YOSHIDA et al.   IN VIVO

Potential use of TIA-1, MFF, microRNA-200a-3p, and microRNA-27 as a novel marker for hepatocellular carcinoma

(2018) Hyosun Tak et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Context-Dependent and Disease-Specific Diversity in Protein Interactions within Stress Granules

(2018) Sebastian Markmiller et al.   CELL

The function and clinical significance of eIF3 in cancer

(2018) Yuting Yin et al.   GENE

Traumatic injury induces stress granule formation and enhances motor dysfunctions in ALS/FTD models

(2018) Eric N Anderson et al.   HUMAN MOLECULAR GENETICS

Chemical compounds that suppress hypoxia-induced stress granule formation enhance cancer drug sensitivity of human cervical cancer HeLa cells

(2018) Shikshya Timalsina et al.   JOURNAL OF BIOCHEMISTRY

Association of USP10 with G3BP2 Inhibits p53 Signaling and Contributes to Poor Outcome in Prostate Cancer

(2018) Ken-ichi Takayama et al.   MOLECULAR CANCER RESEARCH

The TIA1 RNA-Binding Protein Family Regulates EIF2AK2-Mediated Stress Response and Cell Cycle Progression

(2018) Cindy Meyer et al.   MOLECULAR CELL

Development of a stress response therapy targeting aggressive prostate cancer

(2018) Hao G. Nguyen et al.   Science Translational Medicine

G3BP1 promotes tumor progression and metastasis through IL-6/G3BP1/STAT3 signaling axis in renal cell carcinomas

(2018) Yong Wang et al.   Cell Death & Disease

USP10 suppresses tumor progression by inhibiting mTOR activation in hepatocellular carcinoma

(2018) Chang Lu et al.   CANCER LETTERS

A Seven-Gene Signature Aggregates a Subgroup of Stage II Colon Cancers with Stage III

(2018) Sophy Laibe et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

Crosstalk in cancer resistance and metastasis

(2018) Saeed Norouzi et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

TIAR marks nuclear G2/M transition granules and restricts CDK1 activity under replication stress

(2018) Vanesa Lafarga et al.   EMBO REPORTS

Spatial Organization of Single mRNPs at Different Stages of the Gene Expression Pathway

(2018) Srivathsan Adivarahan et al.   MOLECULAR CELL

Dual loss of USP10 and p14ARF protein expression is associated with poor prognosis in patients with small intestinal adenocarcinoma

(2018) Joon Seon Song et al.   TUMOR BIOLOGY

Nitric oxide triggers the assembly of “type II” stress granules linked to decreased cell viability

(2018) Anaïs Aulas et al.   Cell Death & Disease

Association and clinical implication of the USP10 and MSH2 proteins in non‑small cell lung cancer

(2018) Zhi Zeng et al.   Oncology Letters

Stress-specific differences in assembly and composition of stress granules and related foci

(2017) Anaïs Aulas et al.   JOURNAL OF CELL SCIENCE

Isolation of yeast and mammalian stress granule cores

(2017) Joshua R. Wheeler et al.   METHODS

USP10 inhibits lung cancer cell growth and invasion by upregulating PTEN

(2017) Jia Sun et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

The Stress Granule Transcriptome Reveals Principles of mRNA Accumulation in Stress Granules

(2017) Anthony Khong et al.   MOLECULAR CELL

Upregulation of caprin1 expression is associated with poor prognosis in hepatocellular carcinoma

(2017) Ning Tan et al.   PATHOLOGY RESEARCH AND PRACTICE

Stress granule-associated protein G3BP2 regulates breast tumor initiation

(2017) Nisha Gupta et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeting EIF4F complex in non-small cell lung cancer cells

(2017) Lu Dai et al.   Oncotarget

Distinct recruitment of human eIF4E isoforms to processing bodies and stress granules

(2016) Klara Frydryskova et al.   BMC MOLECULAR BIOLOGY

Mutant KRAS Enhances Tumor Cell Fitness by Upregulating Stress Granules

(2016) Elda Grabocka et al.   CELL

The integrated stress response

(2016) Karolina Pakos‐Zebrucka et al.   EMBO REPORTS

Reduced stress granule formation and cell death in fibroblasts with the A382T mutation of TARDBP gene: evidence for loss of TDP-43 nuclear function

(2016) Sandro Orrù et al.   HUMAN MOLECULAR GENETICS

G3BP–Caprin1–USP10 complexes mediate stress granule condensation and associate with 40S subunits

(2016) Nancy Kedersha et al.   JOURNAL OF CELL BIOLOGY

Impairment of stress granule assembly via inhibition of the eIF2alpha phosphorylation sensitizes glioma cells to chemotherapeutic agents

(2016) Fabrício de Almeida Souza Vilas-Boas et al.   JOURNAL OF NEURO-ONCOLOGY

C9ORF72 Regulates Stress Granule Formation and Its Deficiency Impairs Stress Granule Assembly, Hypersensitizing Cells to Stress

(2016) Niran Maharjan et al.   MOLECULAR NEUROBIOLOGY

RNA sequencing of pancreatic adenocarcinoma tumors yields novel expression patterns associated with long-term survival and reveals a role for ANGPTL4

(2016) Marie K. Kirby et al.   Molecular Oncology

Genomic analyses identify molecular subtypes of pancreatic cancer

(2016) Peter Bailey et al.   NATURE

TIA1 oxidation inhibits stress granule assembly and sensitizes cells to stress-induced apoptosis

(2016) Kyoko Arimoto-Matsuzaki et al.   Nature Communications

Vinca alkaloid drugs promote stress-induced translational repression and stress granule formation

(2016) Witold Szaflarski et al.   Oncotarget

The role of eIF3 and its individual subunits in cancer

(2015) John W.B. Hershey   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Phase Separation by Low Complexity Domains Promotes Stress Granule Assembly and Drives Pathological Fibrillization

(2015) Amandine Molliex et al.   CELL

Overexpression of Ras-GTPase-activating protein SH3 domain-binding protein 1 correlates with poor prognosis in gastric cancer patients

(2015) Lingqiang Min et al.   HISTOPATHOLOGY

YB-1 regulates stress granule formation and tumor progression by translationally activating G3BP1

(2015) Syam Prakash Somasekharan et al.   JOURNAL OF CELL BIOLOGY

G3BP1 promotes stress-induced RNA granule interactions to preserve polyadenylated mRNA

(2015) Anaïs Aulas et al.   JOURNAL OF CELL BIOLOGY

Erratum to: Endogenous TDP-43, but not FUS, contributes to stress granule assembly via G3BP

(2015) Anaïs Aulas et al.   Molecular Neurodegeneration

Matrix stiffness drives epithelial–mesenchymal transition and tumour metastasis through a TWIST1–G3BP2 mechanotransduction pathway

(2015) Spencer C. Wei et al.   NATURE CELL BIOLOGY

Alterations in stress granule dynamics driven by TDP-43 and FUS: a link to pathological inclusions in ALS?

(2015) Anaïs Aulas et al.   Frontiers in Cellular Neuroscience

Integrated stress response is critical for gemcitabine resistance in pancreatic ductal adenocarcinoma

(2015) L R Palam et al.   Cell Death & Disease

T-cell intracellular antigens function as tumor suppressor genes

(2015) C Sánchez-Jiménez et al.   Cell Death & Disease

Sorafenib, a multikinase inhibitor, induces formation of stress granules in hepatocarcinoma cells

(2015) Pauline Adjibade et al.   Oncotarget

Prognostic Fifteen-Gene Signature for Early Stage Pancreatic Ductal Adenocarcinoma

(2015) Dung-Tsa Chen et al.   PLoS One

IP-10/CXCL10 induction in human pancreatic cancer stroma influences lymphocytes recruitment and correlates with poor survival

(2015) Serena Lunardi et al.   Oncotarget

Alternative splicing of TIA-1 in human colon cancer regulates VEGF isoform expression, angiogenesis, tumour growth and bevacizumab resistance

(2014) Maryam A. Hamdollah Zadeh et al.   Molecular Oncology

5-Fluorouracil affects assembly of stress granules based on RNA incorporation

(2014) Christian Kaehler et al.   NUCLEIC ACIDS RESEARCH

Control of mRNA turnover: Implication of cytoplasmic RNA granules

(2014) Pauline Adjibade et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Caprin-1, a novel Cyr61-interacting protein, promotes osteosarcoma tumor growth and lung metastasis in mice

(2013) Adam A. Sabile et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Caprin-1 is a novel microRNA-223 target for regulating the proliferation and invasion of human breast cancer cells

(2013) Bo Gong et al.   BIOMEDICINE & PHARMACOTHERAPY

Inhibition of mTORC1 by Astrin and Stress Granules Prevents Apoptosis in Cancer Cells

(2013) Kathrin Thedieck et al.   CELL

Characterization of gene expression and activated signaling pathways in solid-pseudopapillary neoplasm of pancreas

(2013) Minhee Park et al.   MODERN PATHOLOGY

Stress granules and cell signaling: more than just a passing phase?

(2013) Nancy Kedersha et al.   TRENDS IN BIOCHEMICAL SCIENCES

Prognostic significance of USP10 as a tumor-associated marker in gastric carcinoma

(2013) Zhi Zeng et al.   TUMOR BIOLOGY

Gene Expression Classification of Colon Cancer into Molecular Subtypes: Characterization, Validation, and Prognostic Value

(2013) Laetitia Marisa et al.   PLOS MEDICINE

Both G3BP1 and G3BP2 contribute to stress granule formation

(2012) Hideaki Matsuki et al.   GENES TO CELLS

Molecular markers associated with outcome and metastasis in human pancreatic cancer

(2012) Anke Van den Broeck et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Stress Granules Inhibit Apoptosis by Reducing Reactive Oxygen Species Production

(2012) M. Takahashi et al.   MOLECULAR AND CELLULAR BIOLOGY

Endogenous TDP-43, but not FUS, contributes to stress granule assembly via G3BP

(2012) Anaïs Aulas et al.   Molecular Neurodegeneration

Whole-genome analysis informs breast cancer response to aromatase inhibition

(2012) Matthew J. Ellis et al.   NATURE

Comprehensive molecular characterization of human colon and rectal cancer

(2012)   NATURE

Comprehensive molecular portraits of human breast tumours

(2012) Daniel C. Koboldt et al.   NATURE

The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups

(2012) Christina Curtis et al.   NATURE

The unfolded protein response: controlling cell fate decisions under ER stress and beyond

(2012) Claudio Hetz   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Selenite targets eIF4E-binding protein-1 to inhibit translation initiation and induce the assembly of non-canonical stress granules

(2012) Ken Fujimura et al.   NUCLEIC ACIDS RESEARCH

DPEP1 Inhibits Tumor Cell Invasiveness, Enhances Chemosensitivity and Predicts Clinical Outcome in Pancreatic Ductal Adenocarcinoma

(2012) Geng Zhang et al.   PLoS One

Antiangiogenic agents increase breast cancer stem cells via the generation of tumor hypoxia

(2012) S. J. Conley et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Google Goes Cancer: Improving Outcome Prediction for Cancer Patients by Network-Based Ranking of Marker Genes

(2012) Christof Winter et al.   PLoS Computational Biology

Methylation of Cancer-Stem-Cell-Associated Wnt Target Genes Predicts Poor Prognosis in Colorectal Cancer Patients

(2011) Felipe de Sousa E Melo et al.   Cell Stem Cell

TAR DNA-binding protein 43 (TDP-43) regulates stress granule dynamics via differential regulation of G3BP and TIA-1

(2011) Karli K. McDonald et al.   HUMAN MOLECULAR GENETICS

A Genomic Predictor of Response and Survival Following Taxane-Anthracycline Chemotherapy for Invasive Breast Cancer

(2011) Christos Hatzis   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Development and Independent Validation of a Prognostic Assay for Stage II Colon Cancer Using Formalin-Fixed Paraffin-Embedded Tissue

(2011) Richard D. Kennedy et al.   JOURNAL OF CLINICAL ONCOLOGY

Multifactorial Approach to Predicting Resistance to Anthracyclines

(2011) Christine Desmedt et al.   JOURNAL OF CLINICAL ONCOLOGY

Low oxygen levels induce the expression of the embryonic morphogen Nodal

(2011) Daniela F. Quail et al.   MOLECULAR BIOLOGY OF THE CELL

The N-Terminal Domain of G3BP Enhances Cell Motility and Invasion by Posttranscriptional Regulation of BART

(2011) K. Taniuchi et al.   MOLECULAR CANCER RESEARCH

Subtypes of pancreatic ductal adenocarcinoma and their differing responses to therapy

(2011) Eric A Collisson et al.   NATURE MEDICINE

A refined molecular taxonomy of breast cancer

(2011) M Guedj et al.   ONCOGENE

p21WAF1/CIP1 Upregulation through the Stress Granule-Associated Protein CUGBP1 Confers Resistance to Bortezomib-Mediated Apoptosis

(2011) Cristina Gareau et al.   PLoS One

Down-Regulation of ECRG4, a Candidate Tumor Suppressor Gene, in Human Breast Cancer

(2011) Renaud Sabatier et al.   PLoS One

Transcriptome instability in colorectal cancer identified by exon microarray analyses: Associations with splicing factor expression levels and patient survival

(2011) Anita Sveen et al.   Genome Medicine

A genome-wide RNAi screen identifies genes regulating the formation of P bodies in C. elegans and their functions in NMD and RNAi

(2011) Yinyan Sun et al.   Protein & Cell

The chemotherapeutic agent bortezomib induces the formation of stress granules

(2010) Marie-Josée Fournier et al.   Cancer Cell International

Evaluation of a 30-Gene Paclitaxel, Fluorouracil, Doxorubicin, and Cyclophosphamide Chemotherapy Response Predictor in a Multicenter Randomized Trial in Breast Cancer

(2010) A. Tabchy et al.   CLINICAL CANCER RESEARCH

Efficacy of Neoadjuvant Cisplatin in Triple-Negative Breast Cancer

(2010) Daniel P. Silver et al.   JOURNAL OF CLINICAL ONCOLOGY

Intratumor Heterogeneity and Precision of Microarray-Based Predictors of Breast Cancer Biology and Clinical Outcome

(2010) William T. Barry et al.   JOURNAL OF CLINICAL ONCOLOGY

Gene Pathways Associated With Prognosis and Chemotherapy Sensitivity in Molecular Subtypes of Breast Cancer

(2010) Takayuki Iwamoto et al.   JNCI-Journal of the National Cancer Institute

TIA-1 Cytotoxic Granule-Associated RNA Binding Protein Improves the Prognostic Performance of CD8 in Mismatch Repair-Proficient Colorectal Cancer

(2010) Inti Zlobec et al.   PLoS One

BCR-ABL1transcript levels increase in peripheral blood but not in granulocytes after physical exercise in patients with chronic myeloid leukemia

(2010) Sofia Jönsson et al.   SCANDINAVIAN JOURNAL OF CLINICAL & LABORATORY INVESTIGATION

A Six-Gene Signature Predicts Survival of Patients with Localized Pancreatic Ductal Adenocarcinoma

(2010) Jeran K. Stratford et al.   PLOS MEDICINE

Gene expression pathway analysis to predict response to neoadjuvant docetaxel and capecitabine for breast cancer

(2009) Larissa A. Korde et al.   BREAST CANCER RESEARCH AND TREATMENT

Proliferative genes dominate malignancy-risk gene signature in histologically-normal breast tissue

(2009) Dung-Tsa Chen et al.   BREAST CANCER RESEARCH AND TREATMENT

In vivo Antitumor Activity of MEK and Phosphatidylinositol 3-Kinase Inhibitors in Basal-Like Breast Cancer Models

(2009) K. P. Hoeflich et al.   CLINICAL CANCER RESEARCH

Metastasis-Associated Gene Expression Changes Predict Poor Outcomes in Patients with Dukes Stage B and C Colorectal Cancer

(2009) R. N. Jorissen et al.   CLINICAL CANCER RESEARCH

Experimentally Derived Metastasis Gene Expression Profile Predicts Recurrence and Death in Patients With Colon Cancer

(2009) J. Joshua Smith et al.   GASTROENTEROLOGY

Unravelling the ultrastructure of stress granules and associated P-bodies in human cells

(2009) S. Souquere et al.   JOURNAL OF CELL SCIENCE

Multicenter Validation of a 1,550-Gene Expression Profile for Identification of Tumor Tissue of Origin

(2009) Federico A. Monzon et al.   JOURNAL OF CLINICAL ONCOLOGY

An expression module of WIPF1-coexpressed genes identifies patients with favorable prognosis in three tumor types

(2009) Eike Staub et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Genes that mediate breast cancer metastasis to the brain

(2009) Paula D. Bos et al.   NATURE

Association of survival and disease progression with chromosomal instability: A genomic exploration of colorectal cancer

(2009) M. Sheffer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The 76-gene signature defines high-risk patients that benefit from adjuvant tamoxifen therapy

(2008) Yi Zhang et al.   BREAST CANCER RESEARCH AND TREATMENT

The Humoral Immune System Has a Key Prognostic Impact in Node-Negative Breast Cancer

(2008) M. Schmidt et al.   CANCER RESEARCH

Codependent Functions of RSK2 and the Apoptosis-Promoting Factor TIA-1 in Stress Granule Assembly and Cell Survival

(2008) T.S. Karin Eisinger-Mathason et al.   MOLECULAR CELL

Formation of stress granules inhibits apoptosis by suppressing stress-responsive MAPK pathways

(2008) Kyoko Arimoto et al.   NATURE CELL BIOLOGY

Dicer, Drosha, and Outcomes in Patients with Ovarian Cancer

(2008) William M. Merritt et al.   NEW ENGLAND JOURNAL OF MEDICINE

A Precisely Regulated Gene Expression Cassette Potently Modulates Metastasis and Survival in Multiple Solid Cancers

(2008) Kun Yu et al.   PLoS Genetics