Dual loss of USP10 and p14ARF protein expression is associated with poor prognosis in patients with small intestinal adenocarcinoma

Oncogene-induced senescence mediated by c-Myc requires USP10 dependent deubiquitination and stabilization of p14ARF

(2018) Aram Ko et al.   CELL DEATH AND DIFFERENTIATION

Association of USP10 with G3BP2 Inhibits p53 Signaling and Contributes to Poor Outcome in Prostate Cancer

(2018) Ken-ichi Takayama et al.   MOLECULAR CANCER RESEARCH

USP10 inhibits lung cancer cell growth and invasion by upregulating PTEN

(2017) Jia Sun et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Primary small bowel adenocarcinoma: current view on clinical features, risk and prognostic factors, treatment and outcome

(2017) Gustaw Lech et al.   SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY

Potential roles of DNA methylation in the initiation and establishment of replicative senescence revealed by array-based methylome and transcriptome analyses

(2017) Mizuho Sakaki et al.   PLoS One

Molecular Chaperone HSP90 Is Necessary to Prevent Cellular Senescence via Lysosomal Degradation of p14ARF

(2016) Su Yeon Han et al.   CANCER RESEARCH

Small Bowel Adenocarcinoma

(2016) Thomas Aparicio et al.   GASTROENTEROLOGY CLINICS OF NORTH AMERICA

Regulation of the Mdm2-p53 signaling axis in the DNA damage response and tumorigenesis

(2016) Michael I. Carr et al.   Translational Cancer Research

Epigenetic regulation of p14ARF and p16INK4A expression in cutaneous and uveal melanoma

(2015) Mario Venza et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Ubiquitin-specific protease 7 accelerates p14ARFdegradation by deubiquitinating thyroid hormone receptor-interacting protein 12 and promotes hepatocellular carcinoma progression

(2015) Jia-Bin Cai et al.   HEPATOLOGY

Pivotal Role of the Chromatin Protein Nupr1 in Kras-Induced Senescence and Transformation

(2015) Daniel Grasso et al.   Scientific Reports

A comparison of oncogene-induced senescence and replicative senescence: implications for tumor suppression and aging

(2014) David M. Nelson et al.   AGE

Epithelial cell-derived periostin functions as a tumor suppressor in gastric cancer through stabilizing p53 and E-cadherin proteins via the Rb/E2F1/p14ARF/Mdm2 signaling pathway

(2014) Hongjun Lv et al.   CELL CYCLE

MicroRNA-191 promotes pancreatic cancer progression by targeting USP10

(2014) Hua Liu et al.   TUMOR BIOLOGY

Combined Loss of E-cadherin and Aberrant β-Catenin Protein Expression Correlates With a Poor Prognosis for Small Intestinal Adenocarcinomas

(2013) Hee Jin Lee et al.   AMERICAN JOURNAL OF CLINICAL PATHOLOGY

Identification of the methylation of p14ARF promoter as a novel non-invasive biomarker for early detection of lung cancer

(2013) L. Li et al.   Clinical & Translational Oncology

Epithelial-mesenchymal transition phenotype is associated with patient survival in small intestinal adenocarcinoma

(2013) Aeri Kim et al.   PATHOLOGY

Biological significance of promoter hypermethylation of p14/ARF gene: Relationships to p53 mutational status in Tunisian population with colorectal carcinoma

(2013) Ines Chaar et al.   TUMOR BIOLOGY

Prognostic significance of USP10 as a tumor-associated marker in gastric carcinoma

(2013) Zhi Zeng et al.   TUMOR BIOLOGY

Prognostication of Vulvar Cancer Based on p14ARF Status: Molecular Assessment of Transcript and Protein

(2012) André Mourão Lavorato-Rocha et al.   ANNALS OF SURGICAL ONCOLOGY

p14ARF inhibits the growth of lung adenocarcinoma cells harbouring an EGFR L858R mutation by activating a STAT3-dependent pro-apoptotic signalling pathway

(2012) P Ozenne et al.   ONCOGENE

Hypermethylation of the 5′ CpG island of the p14ARF flanking exon 1β in human colorectal cancer displaying a restricted pattern of p53 overexpression concomitant with increased MDM2 expression

(2012) Christine Nyiraneza et al.   Clinical Epigenetics

Beclin1 Controls the Levels of p53 by Regulating the Deubiquitination Activity of USP10 and USP13

(2011) Junli Liu et al.   CELL

Ubiquitin-specific proteases as cancer drug targets

(2011) Wolfgang Sippl et al.   Future Oncology

Second-line chemotherapy with fluorouracil, leucovorin, and irinotecan (FOLFIRI regimen) in patients with advanced small bowel adenocarcinoma after failure of first-line platinum-based chemotherapy

(2010) Aziz Zaanan et al.   CANCER

USP10 Regulates p53 Localization and Stability by Deubiquitinating p53

(2010) Jian Yuan et al.   CELL

Adenocarcinoma of the small intestine: a multi-institutional study of 197 surgically resected cases

(2010) Hee-Kyung Chang et al.   HUMAN PATHOLOGY

Many roads lead to oncogene-induced senescence

(2008) S Courtois-Cox et al.   ONCOGENE