AMCase is a crucial regulator of type 2 immune responses to inhaled house dust mites

The Effect of Chitin Size, Shape, Source and Purification Method on Immune Recognition

(2014) Francisco Alvarez   MOLECULES

Fungal Chitin Dampens Inflammation through IL-10 Induction Mediated by NOD2 and TLR9 Activation

(2014) Jeanette Wagener et al.   PLoS Pathogens

Innate Sensing of Chitin and Chitosan

(2013) Chelsea L. Bueter et al.   PLoS Pathogens

IL-33, but not thymic stromal lymphopoietin or IL-25, is central to mite and peanut allergic sensitization

(2012) Derek K. Chu et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Inflammasome-Activated Caspase 7 Cleaves PARP1 to Enhance the Expression of a Subset of NF-κB Target Genes

(2012) Süheda Erener et al.   MOLECULAR CELL

Allergic host defences

(2012) Noah W. Palm et al.   NATURE

The airway epithelium in asthma

(2012) Bart N Lambrecht et al.   NATURE MEDICINE

IL-33 is processed into mature bioactive forms by neutrophil elastase and cathepsin G

(2012) E. Lefrancais et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

New Paradigms in Type 2 Immunity

(2012) B. Pulendran et al.   SCIENCE

Acidic Mammalian Chitinase Is Not a Critical Target for Allergic Airway Disease

(2011) Lori J. Fitz et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Role of Chitin and Chitinase/Chitinase-Like Proteins in Inflammation, Tissue Remodeling, and Injury

(2011) Chun Geun Lee et al.   Annual Review of Physiology

Chitosan but Not Chitin Activates the Inflammasome by a Mechanism Dependent upon Phagocytosis

(2011) Chelsea L. Bueter et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fungal Chitin from Asthma-Associated Home Environments Induces Eosinophilic Lung Infiltration

(2011) S. J. Van Dyken et al.   JOURNAL OF IMMUNOLOGY

Interleukin-33 biology with potential insights into human diseases

(2011) Gaby Palmer et al.   Nature Reviews Rheumatology

The role of the NLRP3 Inflammasome in the pathogenesis of airway disease

(2011) Mark A. Birrell et al.   PHARMACOLOGY & THERAPEUTICS

Orchestrating house dust mite-associated allergy in the lung

(2011) Lisa G. Gregory et al.   TRENDS IN IMMUNOLOGY

Molecular Mechanism of NLRP3 Inflammasome Activation

(2010) Chengcheng Jin et al.   JOURNAL OF CLINICAL IMMUNOLOGY

IL-33 is a crucial amplifier of innate rather than acquired immunity

(2010) K. Oboki et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mature interleukin-33 is produced by calpain-mediated cleavage in vivo

(2009) Morisada Hayakawa et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Suppression of Interleukin-33 Bioactivity through Proteolysis by Apoptotic Caspases

(2009) Alexander U. Lüthi et al.   IMMUNITY

Interleukin-33 Is Biologically Active Independently of Caspase-1 Cleavage

(2009) Dominique Talabot-Ayer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of breast regression protein 39 (BRP-39)/chitinase 3-like-1 in Th2 and IL-13–induced tissue responses and apoptosis

(2009) Chun Geun Lee et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Acidic Mammalian Chitinase Regulates Epithelial Cell Apoptosis via a Chitinolytic-Independent Mechanism

(2009) D. Hartl et al.   JOURNAL OF IMMUNOLOGY

Chitin Is a Size-Dependent Regulator of Macrophage TNF and IL-10 Production

(2009) C. A. Da Silva et al.   JOURNAL OF IMMUNOLOGY

House dust mite allergen induces asthma via Toll-like receptor 4 triggering of airway structural cells

(2009) Hamida Hammad et al.   NATURE MEDICINE

Caspase-7 Activation by the Nlrc4/Ipaf Inflammasome Restricts Legionella pneumophila Infection

(2009) Anwari Akhter et al.   PLoS Pathogens

Chitin regulation of immune responses: an old molecule with new roles

(2008) Chun Geun Lee et al.   CURRENT OPINION IN IMMUNOLOGY

Targeted Peptidecentric Proteomics Reveals Caspase-7 as a Substrate of the Caspase-1 Inflammasomes

(2008) Mohamed Lamkanfi et al.   MOLECULAR & CELLULAR PROTEOMICS

Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants

(2008) Stephanie C. Eisenbarth et al.   NATURE