CXCR1 and CXCR2 Inhibition by Ladarixin Improves Neutrophil-Dependent Airway Inflammation in Mice
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
CXCR1 and CXCR2 Inhibition by Ladarixin Improves Neutrophil-Dependent Airway Inflammation in Mice
Authors
Keywords
-
Journal
Frontiers in Immunology
Volume 11, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2020-10-02
DOI
10.3389/fimmu.2020.566953
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Randomized, Double-Blind, Placebo-Controlled Study of the Safety, Tolerability, and Clinical Effect of Danirixin in Adults With Acute, Uncomplicated Influenza
- (2019) Grace Roberts et al. Open Forum Infectious Diseases
- The atypical chemokine receptor ACKR2 drives pulmonary fibrosis by tuning influx of CCR2+ and CCR5+ IFNγ-producing γδT cells in mice
- (2018) Remo C. Russo et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- Effect of the CXCR2 antagonist danirixin on symptoms and health status in COPD
- (2018) Aili L. Lazaar et al. EUROPEAN RESPIRATORY JOURNAL
- Inhalation of the prodrug PI3K inhibitor CL27c improves lung function in asthma and fibrosis
- (2018) Carlo C. Campa et al. Nature Communications
- Effects of the CXCR2 antagonist AZD5069 on lung neutrophil recruitment in asthma
- (2017) Henrik Watz et al. PULMONARY PHARMACOLOGY & THERAPEUTICS
- CXCR2 Inhibition – a novel approach to treating CoronAry heart DiseAse (CICADA): study protocol for a randomised controlled trial
- (2017) Jubin P. Joseph et al. Trials
- The effects of a CXCR1/CXCR2 antagonist on neutrophil migration in mild atopic asthmatic subjects
- (2016) Candice M. Todd et al. PULMONARY PHARMACOLOGY & THERAPEUTICS
- Acute exacerbation of COPD
- (2016) Fanny W. Ko et al. RESPIROLOGY
- Apocynin and ebselen reduce influenza A virus-induced lung inflammation in cigarette smoke-exposed mice
- (2016) L. C. Oostwoud et al. Scientific Reports
- CXCR2 Antagonist MK-7123. A Phase 2 Proof-of-Concept Trial for Chronic Obstructive Pulmonary Disease
- (2015) Stephen I. Rennard et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Glucagon induces airway smooth muscle relaxation by nitric oxide and prostaglandin E2
- (2015) D. B. R. Insuela et al. JOURNAL OF ENDOCRINOLOGY
- Neutralizing TNFα restores glucocorticoid sensitivity in a mouse model of neutrophilic airway inflammation
- (2015) L Dejager et al. Mucosal Immunology
- The CXCL8/IL-8 chemokine family and its receptors in inflammatory diseases
- (2014) Remo C Russo et al. Expert Review of Clinical Immunology
- IL-33 Induces Antigen-Specific IL-5+ T Cells and Promotes Allergic-Induced Airway Inflammation Independent of IL-4
- (2014) M. Kurowska-Stolarska et al. JOURNAL OF IMMUNOLOGY
- TH17 Cells Mediate Steroid-Resistant Airway Inflammation and Airway Hyperresponsiveness in Mice
- (2014) L. McKinley et al. JOURNAL OF IMMUNOLOGY
- The complex relationship between inflammation and lung function in severe asthma
- (2014) M L Manni et al. Mucosal Immunology
- CXCL6 antibody neutralization prevents lung inflammation and fibrosis in mice in the bleomycin model
- (2013) Anne-Gaëlle Besnard et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Safety and efficacy of a CXCR2 antagonist in patients with severe asthma and sputum neutrophils: a randomized, placebo-controlled clinical trial
- (2012) P. Nair et al. CLINICAL AND EXPERIMENTAL ALLERGY
- Pathogenesis of chronic obstructive pulmonary disease
- (2012) Rubin M. Tuder et al. JOURNAL OF CLINICAL INVESTIGATION
- Asthma phenotypes: the evolution from clinical to molecular approaches
- (2012) Sally E Wenzel NATURE MEDICINE
- Receptor binding mode and pharmacological characterization of a potent and selective dual CXCR1/CXCR2 non-competitive allosteric inhibitor
- (2011) R Bertini et al. BRITISH JOURNAL OF PHARMACOLOGY
- CC and CXC Chemokines Induce Airway Smooth Muscle Proliferation and Survival
- (2011) Rabih Halwani et al. JOURNAL OF IMMUNOLOGY
- Long-term exposure to cigarette smoke impairs lung function and increases HMGB-1 expression in mice
- (2011) Frank Silva Bezerra et al. RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY
- Mechanism of Neutrophil Recruitment to the Lung After Pulmonary Contusion
- (2011) J. Jason Hoth et al. SHOCK
- A role for sensory nerves in the late asthmatic response
- (2011) Kristof Raemdonck et al. THORAX
- Therapeutic Effects of Evasin-1, a Chemokine Binding Protein, in Bleomycin-Induced Pulmonary Fibrosis
- (2010) Remo C. Russo et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- CXCR2 and CXCR4 antagonistically regulate neutrophil trafficking from murine bone marrow
- (2010) Kyle J. Eash et al. JOURNAL OF CLINICAL INVESTIGATION
- Phosphoinositide 3-kinase γ plays a critical role in bleomycin-induced pulmonary inflammation and fibrosis in mice
- (2010) Remo C. Russo et al. JOURNAL OF LEUKOCYTE BIOLOGY
- New therapies for asthma: is there any progress?
- (2010) Peter J. Barnes TRENDS IN PHARMACOLOGICAL SCIENCES
- Pulmonary fibrosis: pathogenesis, etiology and regulation
- (2009) M S Wilson et al. Mucosal Immunology
- Asthma
- (2009) Christopher H. Fanta NEW ENGLAND JOURNAL OF MEDICINE
- Role of the Chemokine Receptor CXCR2 in Bleomycin-Induced Pulmonary Inflammation and Fibrosis
- (2008) Remo C. Russo et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- The cytokine network in asthma and chronic obstructive pulmonary disease
- (2008) Peter J. Barnes JOURNAL OF CLINICAL INVESTIGATION
- Endotyping asthma: new insights into key pathogenic mechanisms in a complex, heterogeneous disease
- (2008) Gary P Anderson LANCET
- CXCR2 antagonists for the treatment of pulmonary disease
- (2008) R.W. Chapman et al. PHARMACOLOGY & THERAPEUTICS
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started