MiR-21-5p in macrophage-derived extracellular vesicles affects podocyte pyroptosis in diabetic nephropathy by regulating A20

RNA delivery by extracellular vesicles in mammalian cells and its applications

(2020) Killian O’Brien et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Exosome enrichment by ultracentrifugation and size exclusion chromatography

(2018) Murray D Mitchell   Frontiers in Bioscience-Landmark

Emerging role of exosome signalling in maintaining cancer stem cell dynamic equilibrium

(2018) Zhen Sun et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Shedding light on the cell biology of extracellular vesicles

(2018) Guillaume van Niel et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

A20 critically controls microglia activation and inhibits inflammasome-dependent neuroinflammation

(2018) Sofie Voet et al.   Nature Communications

From Inflammasome to Exosome—Does Extracellular Vesicle Secretion Constitute an Inflammasome-Dependent Immune Response?

(2018) Wojciech Cypryk et al.   Frontiers in Immunology

M2 Macrophage-Derived Exosomes Promote Cell Migration and Invasion in Colon Cancer

(2018) Jingqin Lan et al.   CANCER RESEARCH

Issue Information

(2018)   NEPHROLOGY

Exosomes Released from Tumor-Associated Macrophages Transfer miRNAs That Induce a Treg/Th17 Cell Imbalance in Epithelial Ovarian Cancer

(2018) Jieru Zhou et al.   Cancer Immunology Research

Macrophage-Derived miRNA-Containing Exosomes Induce Peritendinous Fibrosis after Tendon Injury through the miR-21-5p/Smad7 Pathway

(2018) Haomin Cui et al.   Molecular Therapy-Nucleic Acids

Long noncoding RNA MALAT1 regulates renal tubular epithelial pyroptosis by modulated miR-23c targeting of ELAVL1 in diabetic nephropathy

(2017) Xue Li et al.   EXPERIMENTAL CELL RESEARCH

The Evolving Complexity of the Podocyte Cytoskeleton

(2017) Christoph Schell et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The role of the complement system in diabetic nephropathy

(2017) Allan Flyvbjerg   Nature Reviews Nephrology

miR-21-5p alleviates leakage of injured brain microvascular endothelial barrier in vitro through suppressing inflammation and apoptosis

(2016) Xintong Ge et al.   BRAIN RESEARCH

Geniposide reduces development of streptozotocin-induced diabetic nephropathy via regulating nuclear factor-kappa B signaling pathways

(2016) Xiaolei Hu et al.   FUNDAMENTAL & CLINICAL PHARMACOLOGY

Versatile roles of extracellular vesicles in cancer

(2016) Nobuyoshi Kosaka et al.   JOURNAL OF CLINICAL INVESTIGATION

miR-21-5p renal expression is associated with fibrosis and renal survival in patients with IgA nephropathy

(2016) Marie-Flore Hennino et al.   Scientific Reports

Genetics of Diabetic Nephropathy: a Long Road of Discovery

(2015) Amy Jayne McKnight et al.   Current Diabetes Reports

FK506 reduces albuminuria through improving podocyte nephrin and podocin expression in diabetic rats

(2015) X.-M. Qi et al.   INFLAMMATION RESEARCH

NLRP3 inflammasome: From a danger signal sensor to a regulatory node of oxidative stress and inflammatory diseases

(2015) Amna Abderrazak et al.   Redox Biology

Cell biology of diabetic nephropathy: Roles of endothelial cells, tubulointerstitial cells and podocytes

(2014) Yoshiro Maezawa et al.   Journal of Diabetes Investigation

Endogenous RNAs Modulate MicroRNA Sorting to Exosomes and Transfer to Acceptor Cells

(2014) Mario Leonardo Squadrito et al.   Cell Reports

Selective extracellular vesicle-mediated export of an overlapping set of microRNAs from multiple cell types

(2012) Jasenka Guduric-Fuchs et al.   BMC GENOMICS

Inflammation and the pathogenesis of diabetic nephropathy

(2012) Jun Wada et al.   CLINICAL SCIENCE

The inflammasome: an integrated view

(2011) Olaf Gross et al.   IMMUNOLOGICAL REVIEWS

Human saliva, plasma and breast milk exosomes contain RNA: uptake by macrophages

(2011) Cecilia Lässer et al.   Journal of Translational Medicine

Spironolactone inhibits hyperglycemia-induced podocyte injury by attenuating ROS production

(2011) J. Toyonaga et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome

(2010) Kiichi Nakahira et al.   NATURE IMMUNOLOGY

Pyroptosis: host cell death and inflammation

(2009) Tessa Bergsbaken et al.   NATURE REVIEWS MICROBIOLOGY

A20: Central Gatekeeper in Inflammation and Immunity

(2008) Beatrice Coornaert et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Multiple polymorphisms in the TNFAIP3 region are independently associated with systemic lupus erythematosus

(2008) Stacy L Musone et al.   NATURE GENETICS