MerTK Expression and ERK Activation Are Essential for the Functional Maturation of Osteopontin‐Producing Reparative Macrophages After Myocardial Infarction

MERTK tyrosine kinase receptor together with TIM4 phosphatidylserine receptor mediates distinct signal transduction pathways for efferocytosis and cell proliferation

(2019) Chihiro Nishi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Macrophage Polarization: Different Gene Signatures in M1(LPS+) vs. Classically and M2(LPS–) vs. Alternatively Activated Macrophages

(2019) Marco Orecchioni et al.   Frontiers in Immunology

Tumor-derived lactate induces M2 macrophage polarization via the activation of the ERK/STAT3 signaling pathway in breast cancer

(2018) Xianmin Mu et al.   CELL CYCLE

IL-10-STAT3-Galectin-3 Axis is Essential for Osteopontin-Producing Reparative Macrophage Polarization After Myocardial Infarction

(2018) Kohsuke Shirakawa et al.   CIRCULATION

The Dual Role of TAM Receptors in Autoimmune Diseases and Cancer: An Overview

(2018) Martha Wium et al.   Cells

Protective Effects of Pterostilbene Against Myocardial Ischemia/Reperfusion Injury in Rats

(2017) Miao Wu et al.   INFLAMMATION

Macrophages in Tissue Repair, Regeneration, and Fibrosis

(2016) Thomas A. Wynn et al.   IMMUNITY

Alternatively activated macrophages determine repair of the infarcted adult murine heart

(2016) Manabu Shiraishi et al.   JOURNAL OF CLINICAL INVESTIGATION

TAM receptors regulate multiple features of microglial physiology

(2016) Lawrence Fourgeaud et al.   NATURE

MerTK cleavage limits proresolving mediator biosynthesis and exacerbates tissue inflammation

(2016) Bishuang Cai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MERTK as negative regulator of human T cell activation

(2015) Raquel Cabezo´n et al.   JOURNAL OF LEUKOCYTE BIOLOGY

ERK Signaling Is Essential for Macrophage Development

(2015) Edward T. Richardson et al.   PLoS One

Systemic and Cardiac Depletion of M2 Macrophage through CSF-1R Signaling Inhibition Alters Cardiac Function Post Myocardial Infarction

(2015) Anne-Laure Leblond et al.   PLoS One

Mer receptor tyrosine kinase mediates both tethering and phagocytosis of apoptotic cells

(2015) I Dransfield et al.   Cell Death & Disease

TAM receptors, Gas6, and protein S: roles in inflammation and hemostasis

(2014) J. H. M. van der Meer et al.   BLOOD

Regulation of Alternative Macrophage Activation by Galectin-3

(2014) A. C. MacKinnon et al.   JOURNAL OF IMMUNOLOGY

Diversification of TAM receptor tyrosine kinase function

(2014) Anna Zagórska et al.   NATURE IMMUNOLOGY

Enhanced Efferocytosis of Apoptotic Cardiomyocytes Through Myeloid-Epithelial-Reproductive Tyrosine Kinase Links Acute Inflammation Resolution to Cardiac Repair After Infarction

(2013) Elaine Wan et al.   CIRCULATION RESEARCH

Molecular Pathways: MERTK Signaling in Cancer

(2013) C. T. Cummings et al.   CLINICAL CANCER RESEARCH

Efficient Clearance of Early Apoptotic Cells by Human Macrophages Requires M2c Polarization and MerTK Induction

(2012) G. Zizzo et al.   JOURNAL OF IMMUNOLOGY

Osteopontin in macrophage function

(2011) Susan R. Rittling   EXPERT REVIEWS IN MOLECULAR MEDICINE

Osteopontin: Correlation with phagocytosis by brain macrophages in a rat model of stroke

(2010) Yoo-Jin Shin et al.   GLIA

Osteopontin Enhances Phagocytosis through a Novel Osteopontin Receptor, the  X 2 Integrin

(2009) L. Schack et al.   JOURNAL OF IMMUNOLOGY

MerTK is required for apoptotic cell–induced T cell tolerance

(2008) Mark A. Wallet et al.   JOURNAL OF EXPERIMENTAL MEDICINE