MERTK as negative regulator of human T cell activation

MerTK inhibition is a novel therapeutic approach for glioblastoma multiforme

(2015) Kristina H. Knubel et al.   Oncotarget

Therapeutic Potential of Tolerogenic Dendritic Cells in IBD: From Animal Models to Clinical Application

(2013) Raquel Cabezón et al.   Clinical & Developmental Immunology

T Cell-Derived Protein S Engages TAM Receptor Signaling in Dendritic Cells to Control the Magnitude of the Immune Response

(2013) Eugenio A. Carrera Silva et al.   IMMUNITY

MerTK inhibition in tumor leukocytes decreases tumor growth and metastasis

(2013) Rebecca S. Cook et al.   JOURNAL OF CLINICAL INVESTIGATION

MERTK receptor tyrosine kinase is a therapeutic target in melanoma

(2013) Jennifer Schlegel et al.   JOURNAL OF CLINICAL INVESTIGATION

SUMOylation regulates the chromatin occupancy and anti-proliferative gene programs of glucocorticoid receptor

(2013) Ville Paakinaho et al.   NUCLEIC ACIDS RESEARCH

Inhibition of MerTK increases chemosensitivity and decreases oncogenic potential in T-cell acute lymphoblastic leukemia

(2013) L N Brandao et al.   Blood Cancer Journal

Therapeutic efficacy of Tyro3, Axl, and Mer tyrosine kinase agonists in collagen-induced arthritis

(2012) B. T. van den Brand et al.   ARTHRITIS AND RHEUMATISM

Proteomic Profiling of Androgen-independent Prostate Cancer Cell Lines Reveals a Role for Protein S during the Development of High Grade and Castration-resistant Prostate Cancer

(2012) Punit Saraon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Efficient Clearance of Early Apoptotic Cells by Human Macrophages Requires M2c Polarization and MerTK Induction

(2012) G. Zizzo et al.   JOURNAL OF IMMUNOLOGY

Gram-Negative Enterobacteria Induce Tolerogenic Maturation in Dexamethasone Conditioned Dendritic Cells

(2012) Raquel Cabezón et al.   PLoS One

The glucocorticoid dexamethasone programs human dendritic cells for enhanced phagocytosis of apoptotic neutrophils and inflammatory response

(2011) Judit Hodrea et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Comparative study of clinical grade human tolerogenic dendritic cells

(2011) M Naranjo-Gómez et al.   Journal of Translational Medicine

Generation and characterisation of therapeutic tolerogenic dendritic cells for rheumatoid arthritis

(2010) R. A. Harry et al.   ANNALS OF THE RHEUMATIC DISEASES

Therapeutic effect of tolerogenic dendritic cells in established collagen-induced arthritis is associated with a reduction in Th17 responses

(2010) Jeroen N. Stoop et al.   ARTHRITIS AND RHEUMATISM

TNF-α, IL-6, and IL-1 expression is inhibited by GAS6 in monocytes/macrophages

(2010) Federica Alciato et al.   JOURNAL OF LEUKOCYTE BIOLOGY

The receptor tyrosine kinase MerTK regulates dendritic cell production of BAFF

(2009) P. R. Gohlke et al.   AUTOIMMUNITY

Lack of Protein S in mice causes embryonic lethal coagulopathy and vascular dysgenesis

(2009) Tal Burstyn-Cohen et al.   JOURNAL OF CLINICAL INVESTIGATION

Glucocorticoids Induce Protein S-Dependent Phagocytosis of Apoptotic Neutrophils by Human Macrophages

(2009) A. McColl et al.   JOURNAL OF IMMUNOLOGY

Axl and Growth Arrest Specific Gene 6 Are Frequently Overexpressed in Human Gliomas and Predict Poor Prognosis in Patients with Glioblastoma Multiforme

(2008) M. Hutterer et al.   CLINICAL CANCER RESEARCH

MerTK is required for apoptotic cell–induced T cell tolerance

(2008) Mark A. Wallet et al.   JOURNAL OF EXPERIMENTAL MEDICINE