Arginine methylation of SHANK2 by PRMT7 promotes human breast cancer metastasis through activating endosomal FAK signalling

PRMT7 methylates eukaryotic translation initiation factor 2α and regulates its role in stress granule formation

(2019) Nasim Haghandish et al.   MOLECULAR BIOLOGY OF THE CELL

PRMT7 as a unique member of the protein arginine methyltransferase family: A review

(2019) Kanishk Jain et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

PRMT7 methylates and suppresses GLI2 binding to SUFU thereby promoting its activation

(2019) Tuan Anh Vuong et al.   CELL DEATH AND DIFFERENTIATION

Anti-tumor Activity of the Type I PRMT Inhibitor, GSK3368715, Synergizes with PRMT5 Inhibition through MTAP Loss

(2019) Andrew Fedoriw et al.   CANCER CELL

Prmt7 promotes myoblast differentiation via methylation of p38MAPK on arginine residue 70

(2019) Hyeon-Ju Jeong et al.   CELL DEATH AND DIFFERENTIATION

PRMTs and Arginine Methylation: Cancer’s Best-Kept Secret?

(2019) James Jarrold et al.   TRENDS IN MOLECULAR MEDICINE

N-glycosylation-defective splice variants of neuropilin-1 promote metastasis by activating endosomal signals

(2019) Xiuping Huang et al.   Nature Communications

Mechanisms of clathrin-mediated endocytosis

(2018) Marko Kaksonen et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

SWISS-MODEL: homology modelling of protein structures and complexes

(2018) Andrew Waterhouse et al.   NUCLEIC ACIDS RESEARCH

Arginine methylation is required for canonical Wnt signaling and endolysosomal trafficking

(2018) Lauren V. Albrecht et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Trafficking of Adhesion and Growth Factor Receptors and Their Effector Kinases

(2018) Christina Schoenherr et al.   Annual Review of Cell and Developmental Biology

Automethylation of protein arginine methyltransferase 7 and its impact on breast cancer progression

(2017) Pengyu Geng et al.   FASEB JOURNAL

Reciprocal regulation of signaling and endocytosis: Implications for the evolving cancer cell

(2017) Sandra L. Schmid   JOURNAL OF CELL BIOLOGY

Arginine Methylation: The Coming of Age

(2017) Roméo S. Blanc et al.   MOLECULAR CELL

A critical role of spinal Shank2 proteins in NMDA-induced pain hypersensitivity

(2017) Seo-Yeon Yoon et al.   Molecular Pain

SHANK proteins limit integrin activation by directly interacting with Rap1 and R-Ras

(2017) Johanna Lilja et al.   NATURE CELL BIOLOGY

SHANK proteins: roles at the synapse and in autism spectrum disorder

(2017) Patricia Monteiro et al.   NATURE REVIEWS NEUROSCIENCE

Genomic Characterization of Esophageal Squamous Cell Carcinoma Reveals Critical Genes Underlying Tumorigenesis and Poor Prognosis

(2016) Hai-De Qin et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Prmt7 Deficiency Causes Reduced Skeletal Muscle Oxidative Metabolism and Age-Related Obesity

(2016) Hyeon-Ju Jeong et al.   DIABETES

Adult restoration of Shank3 expression rescues selective autistic-like phenotypes

(2016) Yuan Mei et al.   NATURE

FAK, talin and PIPKIγ regulate endocytosed integrin activation to polarize focal adhesion assembly

(2016) Guilherme P. F. Nader et al.   NATURE CELL BIOLOGY

Endosomes: Emerging Platforms for Integrin-Mediated FAK Signalling

(2016) Jonna Alanko et al.   TRENDS IN CELL BIOLOGY

Role of the pH in state-dependent blockade of hERG currents

(2016) Yibo Wang et al.   Scientific Reports

Integrin endosomal signalling suppresses anoikis

(2015) Jonna Alanko et al.   NATURE CELL BIOLOGY

PYK2 sustains endosomal-derived receptor signalling and enhances epithelial-to-mesenchymal transition

(2015) Nandini Verma et al.   Nature Communications

Protein arginine methyltransferase 7 promotes breast cancer cell invasion through the induction of MMP9 expression

(2015) R. Mitchell Baldwin et al.   Oncotarget

PRMT7 Induces Epithelial-to-Mesenchymal Transition and Promotes Metastasis in Breast Cancer

(2014) R. Yao et al.   CANCER RESEARCH

SHANK3Gene Mutations Associated with Autism Facilitate Ligand Binding to the Shank3 Ankyrin Repeat Region

(2013) Marie Germaine Mameza et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CHARMM36 all-atom additive protein force field: Validation based on comparison to NMR data

(2013) Jing Huang et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Trans-tail regulation of MLL4-catalyzed H3K4 methylation by H4R3 symmetric dimethylation is mediated by a tandem PHD of MLL4

(2012) S. S. Dhar et al.   GENES & DEVELOPMENT

Protein Arginine Methyltransferase 7 Regulates Cellular Response to DNA Damage by Methylating Promoter Histones H2A and H4 of the Polymerase δ Catalytic Subunit Gene,POLD1

(2012) Vrajesh Karkhanis et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

β1 Integrin/FAK/cortactin signaling is essential for human head and neck cancer resistance to radiotherapy

(2012) Iris Eke et al.   JOURNAL OF CLINICAL INVESTIGATION

Autistic-like behaviours and hyperactivity in mice lacking ProSAP1/Shank2

(2012) Michael J. Schmeisser et al.   NATURE

Autistic-like social behaviour in Shank2-mutant mice improved by restoring NMDA receptor function

(2012) Hyejung Won et al.   NATURE

Cortactin as a Target for FAK in the Regulation of Focal Adhesion Dynamics

(2012) Alok Tomar et al.   PLoS One

Tyrosine phosphorylation of cortactin by the FAK-Src complex at focal adhesions regulates cell motility

(2011) Wenqi Wang et al.   BMC CELL BIOLOGY

Convergence and error estimation in free energy calculations using the weighted histogram analysis method

(2011) Fangqiang Zhu et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

The 'ins' and 'outs' of podosomes and invadopodia: characteristics, formation and function

(2011) Danielle A. Murphy et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Molecular mechanism and physiological functions of clathrin-mediated endocytosis

(2011) Harvey T. McMahon et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

βPix Up-regulates Na+/H+Exchanger 3 through a Shank2-mediated Protein-Protein Interaction

(2010) Jung-Soo Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The endocytic matrix

(2010) Giorgio Scita et al.   NATURE

MET signalling: principles and functions in development, organ regeneration and cancer

(2010) Livio Trusolino et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

CHARMM general force field: A force field for drug-like molecules compatible with the CHARMM all-atom additive biological force fields

(2009) K. Vanommeslaeghe et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Protein Arginine Methylation in Mammals: Who, What, and Why

(2009) Mark T. Bedford et al.   MOLECULAR CELL