Identification of Penicillin Binding Protein 4 (PBP4) as a critical factor for Staphylococcus aureus bone invasion during osteomyelitis in mice

Osteocyte necrosis triggers osteoclast-mediated bone loss through macrophage-inducible C-type lectin

(2020) Darja Andreev et al.   JOURNAL OF CLINICAL INVESTIGATION

2018 International Consensus Meeting on Musculoskeletal Infection: Research Priorities from the General Assembly Questions

(2019) Edward M. Schwarz et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

MyD88 and IL-1R signaling drive antibacterial immunity and osteoclast-driven bone loss during Staphylococcus aureus osteomyelitis

(2019) Nicole E. Putnam et al.   PLoS Pathogens

An in vitro platform for elucidating the molecular genetics of S. aureus invasion of the osteocyte lacuno-canalicular network during chronic osteomyelitis

(2019) Elysia A Masters et al.   Nanomedicine-Nanotechnology Biology and Medicine

Mechanisms of Immune Evasion and Bone Tissue Colonization That Make Staphylococcus aureus the Primary Pathogen in Osteomyelitis

(2019) Gowrishankar Muthukrishnan et al.   Current Osteoporosis Reports

Immunotherapy synergizes with debridement and antibiotic therapy in a murine 1-stage exchange model of MRSA implant-associated osteomyelitis

(2018) Noriaki Yokogawa et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Peptidoglycan synthesis drives an FtsZ-treadmilling-independent step of cytokinesis

(2018) João M. Monteiro et al.   NATURE

Structural and kinetic analyses of penicillin-binding protein 4 (PBP4)-mediated antibiotic resistance in Staphylococcus aureus

(2018) J. Andrew N. Alexander et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Evidence of Staphylococcus Aureus Deformation, Proliferation, and Migration in Canaliculi of Live Cortical Bone in Murine Models of Osteomyelitis

(2017) Karen L de Mesy Bentley et al.   JOURNAL OF BONE AND MINERAL RESEARCH

PBP 4 Mediates High-Level Resistance to New-Generation Cephalosporins in Staphylococcus aureus

(2016) Liana C. Chan et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Collective cell durotaxis emerges from long-range intercellular force transmission

(2016) R. Sunyer et al.   SCIENCE

A novel murine model of established Staphylococcal bone infection in the presence of a fracture fixation plate to study therapies utilizing antibiotic-laden spacers after revision surgery

(2015) Jason A. Inzana et al.   BONE

Quantifying the natural history of biofilm formation in vivo during the establishment of chronic implant-associatedStaphylococcus aureusosteomyelitis in mice to identify critical pathogen and host factors

(2015) Kohei Nishitani et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Mechanical crack propagation drives millisecond daughter cell separation in Staphylococcus aureus

(2015) X. Zhou et al.   SCIENCE

Bacterial Cell Enlargement Requires Control of Cell Wall Stiffness Mediated by Peptidoglycan Hydrolases

(2015) Richard Wheeler et al.   mBio

Passive immunization with anti-glucosaminidase monoclonal antibodies protects mice from implant-associated osteomyelitis by mediating opsonophagocytosis ofStaphylococcus aureusmegaclusters

(2014) John J. Varrone et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

High vancomycin minimum inhibitory concentration is associated with poor outcome in patients with methicillin-susceptible Staphylococcus aureus bacteremia regardless of treatment

(2014) Juan José Castón et al.   SCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES

Evolution in Fast Forward: a Potential Role for Mutators in Accelerating Staphylococcus aureus Pathoadaptation

(2012) G. S. Canfield et al.   JOURNAL OF BACTERIOLOGY

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

A play in four acts: Staphylococcus aureus abscess formation

(2011) Alice G. Cheng et al.   TRENDS IN MICROBIOLOGY

Outcome of orthopedic implant infections due to different staphylococci

(2010) Dorota Teterycz et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

Teichoic acids are temporal and spatial regulators of peptidoglycan cross-linking in Staphylococcus aureus

(2010) M. L. Atilano et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Outcome of a Second Two-stage Reimplantation for Periprosthetic Knee Infection

(2009) Khalid Azzam et al.   CLINICAL ORTHOPAEDICS AND RELATED RESEARCH

Genetic requirements for Staphylococcus aureus abscess formation and persistence in host tissues

(2009) Alice G. Cheng et al.   FASEB JOURNAL

Molecular Basis for the Role of Staphylococcus aureus Penicillin Binding Protein 4 in Antimicrobial Resistance

(2009) V. Navratna et al.   JOURNAL OF BACTERIOLOGY

Molecular Characterization of a Novel Staphylococcus Aureus Surface Protein (SasC) Involved in Cell Aggregation and Biofilm Accumulation

(2009) Katrin Schroeder et al.   PLoS One

Quorum Sensing in Staphylococci

(2008) Richard P. Novick et al.   Annual Review of Genetics

Periprosthetic Joint Infection: The Incidence, Timing, and Predisposing Factors

(2008) Luis Pulido et al.   CLINICAL ORTHOPAEDICS AND RELATED RESEARCH

agr-Mediated Dispersal of Staphylococcus aureus Biofilms

(2008) Blaise R. Boles et al.   PLoS Pathogens

Quantitative mouse model of implant-associated osteomyelitis and the kinetics of microbial growth, osteolysis, and humoral immunity

(2007) Dan Li et al.   JOURNAL OF ORTHOPAEDIC RESEARCH