Osteocyte necrosis triggers osteoclast-mediated bone loss through macrophage-inducible C-type lectin

C-Type Lectin-Like Receptors: Head or Tail in Cell Death Immunity

(2020) Marion Drouin et al.   Frontiers in Immunology

Autoregulation of Osteocyte Sema3A Orchestrates Estrogen Action and Counteracts Bone Aging

(2019) Mikihito Hayashi et al.   Cell Metabolism

3Dscript: animating 3D/4D microscopy data using a natural-language-based syntax

(2019) Benjamin Schmid et al.   NATURE METHODS

Analysis of early stage osteonecrosis of the human femoral head and the mechanism of femoral head collapse

(2018) Cheng Wang et al.   International Journal of Biological Sciences

Mechanically induced autophagy is associated with ATP metabolism and cellular viability in osteocytes in vitro

(2018) Bingbing Zhang et al.   Redox Biology

Damage-Associated Molecular Patterns in Inflammatory Diseases

(2018) Jong Seong Roh et al.   Immune Network

Osteoclast profile of medication-related osteonecrosis of the jaw secondary to bisphosphonate therapy: a comparison with osteoradionecrosis and osteomyelitis

(2017) Christian Gross et al.   Journal of Translational Medicine

Intracellular metabolite β-glucosylceramide is an endogenous Mincle ligand possessing immunostimulatory activity

(2017) Masahiro Nagata et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Macrophage Inducible C-Type Lectin As a Multifunctional Player in Immunity

(2017) Emmanuel C. Patin et al.   Frontiers in Immunology

Mincle-mediated anti-inflammatory IL-10 response counter-regulates IL-12 in vitro

(2016) Emmanuel C Patin et al.   Innate Immunity

Pannexin-1 and P2X7-Receptor Are Required for Apoptotic Osteocytes in Fatigued Bone to Trigger RANKL Production in Neighboring Bystander Osteocytes

(2016) Wing Yee Cheung et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Severe compromise of preosteoblasts in a surgical mouse model of bisphosphonate-associated osteonecrosis of the jaw

(2016) Luis A. Córdova et al.   JOURNAL OF CRANIO-MAXILLOFACIAL SURGERY

Fully Automated Evaluation of Total Glomerular Number and Capillary Tuft Size in Nephritic Kidneys Using Lightsheet Microscopy

(2016) Anika Klingberg et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

CellTracker (not only) for dummies

(2015) Filippo Piccinini et al.   BIOINFORMATICS

Development of a Mouse Model of Ischemic Osteonecrosis

(2015) Nobuhiro Kamiya et al.   CLINICAL ORTHOPAEDICS AND RELATED RESEARCH

Mitochondrial Complex I Activity Suppresses Inflammation and Enhances Bone Resorption by Shifting Macrophage-Osteoclast Polarization

(2014) Zixue Jin et al.   Cell Metabolism

The Macrophage-Inducible C-Type Lectin, Mincle, Is an Essential Component of the Innate Immune Response to Candida albicans

(2014) C. A. Wells et al.   JOURNAL OF IMMUNOLOGY

Fracture healing: mechanisms and interventions

(2014) Thomas A. Einhorn et al.   Nature Reviews Rheumatology

Bone Microstructure and Regional Distribution of Osteoblast and Osteoclast Activity in the Osteonecrotic Femoral Head

(2014) Cheng Wang et al.   PLoS One

COMP-Angiopoietin1 Potentiates the Effects of Bone Morphogenic Protein-2 on Ischemic Necrosis of the Femoral Head in Rats

(2014) Lu Zhou et al.   PLoS One

Tmem64 Modulates Calcium Signaling during RANKL-Mediated Osteoclast Differentiation

(2013) Hyunsoo Kim et al.   Cell Metabolism

The role of estrogen and androgen receptors in bone health and disease

(2013) Stavros C. Manolagas et al.   Nature Reviews Endocrinology

Moonlighting osteoclasts as undertakers of apoptotic cells

(2012) Ulrike Harre et al.   AUTOIMMUNITY

Osteocyte apoptosis

(2012) Robert L. Jilka et al.   BONE

RSK2 protects mice against TNF-induced bone loss

(2012) C. Bohm et al.   JOURNAL OF CELL SCIENCE

Cell line IDG-SW3 replicates osteoblast-to-late-osteocyte differentiation in vitro and accelerates bone formation in vivo

(2011) Stacey M Woo et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Matrix-embedded cells control osteoclast formation

(2011) Jinhu Xiong et al.   NATURE MEDICINE

Evidence for osteocyte regulation of bone homeostasis through RANKL expression

(2011) Tomoki Nakashima et al.   NATURE MEDICINE

Bisphosphonates Cause Osteonecrosis of the Jaw-Like Disease in Mice

(2010) Yanming Bi et al.   AMERICAN JOURNAL OF PATHOLOGY

Pattern Recognition Receptors and Inflammation

(2010) Osamu Takeuchi et al.   CELL

The amazing osteocyte

(2010) Lynda F Bonewald   JOURNAL OF BONE AND MINERAL RESEARCH

Cutting Edge: Mincle Is Essential for Recognition and Adjuvanticity of the Mycobacterial Cord Factor and its Synthetic Analog Trehalose-Dibehenate

(2010) H. Schoenen et al.   JOURNAL OF IMMUNOLOGY

Oral Bisphosphonate–Associated Osteonecrosis of the Jaw After Implant Surgery: A Case Report and Literature Review

(2010) Alberto Bedogni et al.   JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY

Circulating mitochondrial DAMPs cause inflammatory responses to injury

(2010) Qin Zhang et al.   NATURE

Altered skeletal expression of sclerostin and its link to radiographic progression in ankylosing spondylitis

(2009) Heiner Appel et al.   ARTHRITIS AND RHEUMATISM

Histologic and histomorphometric features of bisphosphonate-related osteonecrosis of the jaws: An analysis of 31 cases with confocal laser scanning microscopy

(2009) G. Favia et al.   BONE

Osteocyte apoptosis and control of bone resorption following ovariectomy in mice

(2009) K.B. Emerton et al.   BONE

Direct recognition of the mycobacterial glycolipid, trehalose dimycolate, by C-type lectin Mincle

(2009) Eri Ishikawa et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Coordination of PGC-1β and iron uptake in mitochondrial biogenesis and osteoclast activation

(2009) Kiyo-aki Ishii et al.   NATURE MEDICINE

Natural History of Osteonecrosis of the Jaw in Patients With Multiple Myeloma

(2008) Ashraf Badros et al.   JOURNAL OF CLINICAL ONCOLOGY

Sensing necrosis with Mincle

(2008) Gordon D Brown   NATURE IMMUNOLOGY

Mincle is an ITAM-coupled activating receptor that senses damaged cells

(2008) Sho Yamasaki et al.   NATURE IMMUNOLOGY