Structural and kinetic analyses of penicillin-binding protein 4 (PBP4)-mediated antibiotic resistance in Staphylococcus aureus

Genetic Diversity among Staphylococcus aureus Isolates Showing Oxacillin and/or Cefoxitin Resistance Not Linked to the Presence of mec Genes

(2018) M. Angeles Argudín et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

PBP4 activity and its overexpression are necessary for PBP4-mediated high-level β-lactam resistance

(2018) Li Basuino et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Identification of a Functionally Unique Family of Penicillin-Binding Proteins

(2017) Michael A. Welsh et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

PBP 4 Mediates High-Level Resistance to New-Generation Cephalosporins in Staphylococcus aureus

(2016) Liana C. Chan et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Identification of non-PBP2a resistance mechanisms in Staphylococcus aureus after serial passage with ceftaroline: involvement of other PBPs

(2016) Sushmita D. Lahiri et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Dali server update

(2016) Liisa Holm et al.   NUCLEIC ACIDS RESEARCH

Whole-Genome Sequencing of Methicillin-Resistant Staphylococcus aureus Resistant to Fifth-Generation Cephalosporins Reveals Potential Non-mecA Mechanisms of Resistance

(2016) Alexander L. Greninger et al.   PLoS One

Detection ofmecA- andmecC-Positive Methicillin-Resistant Staphylococcus aureus (MRSA) Isolates by the New Xpert MRSA Gen 3 PCR Assay: TABLE 1

(2015) Karsten Becker et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Staphylococcus aureus Survives with a Minimal Peptidoglycan Synthesis Machine but Sacrifices Virulence and Antibiotic Resistance

(2015) Patricia Reed et al.   PLoS Pathogens

Reduction of the Peptidoglycan Crosslinking Causes a Decrease in Stiffness of the Staphylococcus aureus Cell Envelope

(2014) Peter Loskill et al.   BIOPHYSICAL JOURNAL

Detection of Lipid-Linked Peptidoglycan Precursors by Exploiting an Unexpected Transpeptidase Reaction

(2014) Yuan Qiao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Deciphering key features in protein structures with the new ENDscript server

(2014) Xavier Robert et al.   NUCLEIC ACIDS RESEARCH

ThePDB_REDOserver for macromolecular structure model optimization

(2014) Robbie P. Joosten et al.   IUCrJ

How good are my data and what is the resolution?

(2013) Philip R. Evans et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Decision making inxia2

(2013) Graeme Winter et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Fortifying the wall: synthesis, regulation and degradation of bacterial peptidoglycan

(2013) Solmaz Sobhanifar et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Towards automated crystallographic structure refinement withphenix.refine

(2012) Pavel V. Afonine et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Structural Perspective of Peptidoglycan Biosynthesis and Assembly

(2012) Andrew L. Lovering et al.   Annual Review of Biochemistry

A Highly Conserved Interaction Involving the Middle Residue of the SXN Active-Site Motif Is Crucial for Function of Class B Penicillin-Binding Proteins: Mutational and Computational Analysis of PBP 2 from N. gonorrhoeae

(2012) Joshua Tomberg et al.   BIOCHEMISTRY

Overview of theCCP4 suite and current developments

(2011) Martyn D. Winn et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Loss of Function of the GdpP Protein Leads to Joint β-Lactam/Glycopeptide Tolerance in Staphylococcus aureus

(2011) J. M. Griffiths et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Comparative effectiveness of nafcillin or cefazolin versus vancomycin in methicillin-susceptible Staphylococcus aureus bacteremia

(2011) Marin L Schweizer et al.   BMC INFECTIOUS DISEASES

Ceftaroline fosamil: a new broad-spectrum cephalosporin

(2011) J. B. Laudano   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

LigPlot+: Multiple Ligand–Protein Interaction Diagrams for Drug Discovery

(2011) Roman A. Laskowski et al.   Journal of Chemical Information and Modeling

XDS

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

A mecA-Negative Strain of Methicillin-Resistant Staphylococcus aureus with High-Level  -Lactam Resistance Contains Mutations in Three Genes

(2010) R. Banerjee et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Crystal Structures of Covalent Complexes of β-Lactam Antibiotics withEscherichia coliPenicillin-Binding Protein 5: Toward an Understanding of Antibiotic Specificity

(2010) George Nicola et al.   BIOCHEMISTRY

MolProbity: all-atom structure validation for macromolecular crystallography

(2009) Vincent B. Chen et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Molecular Basis for the Role of Staphylococcus aureus Penicillin Binding Protein 4 in Antimicrobial Resistance

(2009) V. Navratna et al.   JOURNAL OF BACTERIOLOGY

Crystal Structures of Penicillin-Binding Protein 6 fromEscherichia coli

(2009) Yu Chen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

In Vitro Selection and Characterization of Ceftobiprole-Resistant Methicillin-Resistant Staphylococcus aureus

(2008) R. Banerjee et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Staphylococcus aureus PBP4 Is Essential for  -Lactam Resistance in Community-Acquired Methicillin-Resistant Strains

(2008) G. Memmi et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY