Hepatocyte-like cells derived from human induced pluripotent stem cells using small molecules: implications of a transcriptomic study

Small molecule-induced cellular fate reprogramming: promising road leading to Rome

(2018) Xiang Li et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Biotechnology Challenges to In Vitro Maturation of Hepatic Stem Cells

(2018) Chen Chen et al.   GASTROENTEROLOGY

Cell fate decisions of human iPSC-derived bipotential hepatoblasts depend on cell density

(2018) Nina Graffmann et al.   PLoS One

In Vitro Pluripotent Stem Cell Differentiation to Hepatocyte Ceases Further Maturation at an Equivalent Stage of E15 in Mouse Embryonic Liver Development

(2018) Ravali Raju et al.   STEM CELLS AND DEVELOPMENT

Incorporating population-level genetic variability within laboratory models in toxicology: From the individual to the population

(2018) Peter Dornbos et al.   TOXICOLOGY

Generation of nine induced pluripotent stem cell lines as an ethnic diversity panel

(2018) Xiugong Gao et al.   Stem Cell Research

Stem cell-derived models to improve mechanistic understanding and prediction of human drug-induced liver injury

(2016) Christopher Goldring et al.   HEPATOLOGY

Clinical Application of Pluripotent Stem Cells

(2016) Laia Tolosa et al.   TRANSPLANTATION

Orchestrating liver development

(2015) M. Gordillo et al.   DEVELOPMENT

Gene networks and transcription factor motifs defining the differentiation of stem cells into hepatocyte-like cells

(2015) Patricio Godoy et al.   JOURNAL OF HEPATOLOGY

Phenotypic and functional analyses show stem cell-derived hepatocyte-like cells better mimic fetal rather than adult hepatocytes

(2015) Melissa Baxter et al.   JOURNAL OF HEPATOLOGY

One Standardized Differentiation Procedure Robustly Generates Homogenous Hepatocyte Cultures Displaying Metabolic Diversity from a Large Panel of Human Pluripotent Stem Cells

(2015) Annika Asplund et al.   Stem Cell Reviews and Reports

Morphological and Functional Characterization and Assessment of iPSC-Derived Hepatocytes forIn VitroToxicity Testing

(2015) Jingtao Lu et al.   TOXICOLOGICAL SCIENCES

One Standardized Differentiation Procedure Robustly Generates Homogenous Hepatocyte Cultures Displaying Metabolic Diversity from a Large Panel of Human Pluripotent Stem Cells

(2015) Annika Asplund et al.   Stem Cell Reviews and Reports

Small-Molecule-Driven Hepatocyte Differentiation of Human Pluripotent Stem Cells

(2015) Richard Siller et al.   Stem Cell Reports

Pluripotent stem cell-derived hepatocyte-like cells

(2014) R.E. Schwartz et al.   BIOTECHNOLOGY ADVANCES

CellNet: Network Biology Applied to Stem Cell Engineering

(2014) Patrick Cahan et al.   CELL

Incorporating Population Variability and Susceptible Subpopulations into Dosimetry for High-Throughput Toxicity Testing

(2014) Barbara A. Wetmore et al.   TOXICOLOGICAL SCIENCES

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

Efficient Generation of Functional Hepatocytes From Human Embryonic Stem Cells and Induced Pluripotent Stem Cells by HNF4α Transduction

(2011) Kazuo Takayama et al.   MOLECULAR THERAPY

Epigenetic Mechanisms of Mouse Interstrain Variability in Genotoxicity of the Environmental Toxicant 1,3-Butadiene

(2011) Igor Koturbash et al.   TOXICOLOGICAL SCIENCES

Efficient generation of hepatocyte-like cells from human induced pluripotent stem cells

(2009) Zhihua Song et al.   CELL RESEARCH

Highly efficient generation of human hepatocyte-like cells from induced pluripotent stem cells

(2009) Karim Si-Tayeb et al.   HEPATOLOGY

Generation of functional human hepatic endoderm from human induced pluripotent stem cells

(2009) Gareth J. Sullivan et al.   HEPATOLOGY

Generation of functional hepatocytes from human embryonic stem cells under chemically defined conditions that recapitulate liver development

(2009) Thomas Touboul et al.   HEPATOLOGY

What is principal component analysis?

(2008) Markus Ringnér   NATURE BIOTECHNOLOGY