COCO enhances the efficiency of photoreceptor precursor differentiation in early human embryonic stem cell-derived retinal organoids

Patient-Specific Retinal Organoids Recapitulate Disease Features of Late-Onset Retinitis Pigmentosa

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CRX Expression in Pluripotent Stem Cell-Derived Photoreceptors Marks a Transplantable Subpopulation of Early Cones

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A recurrent arcuate retinopathy in familial cone-rod dystrophy secondary to heterozygous CRX deletion

(2019) Arif O. Khan et al.   OPHTHALMIC GENETICS

Stem cell-based retina models

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Human brain organoids on a chip reveal the physics of folding

(2018) Eyal Karzbrun et al.   Nature Physics

Gene Correction Reverses Ciliopathy and Photoreceptor Loss in iPSC-Derived Retinal Organoids from Retinitis Pigmentosa Patients

(2018) Wen-Li Deng et al.   Stem Cell Reports

Characterization and Transplantation of CD73-Positive Photoreceptors Isolated from Human iPSC-Derived Retinal Organoids

(2018) Giuliana Gagliardi et al.   Stem Cell Reports

Stemming retinal regeneration with pluripotent stem cells

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Modeling human disease using organotypic cultures

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Recruitment of Rod Photoreceptors from Short-Wavelength-Sensitive Cones during the Evolution of Nocturnal Vision in Mammals

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Differentiation of human embryonic stem cells into cone photoreceptors through simultaneous inhibition of BMP, TGFβ and Wnt signaling

(2015) Shufeng Zhou et al.   DEVELOPMENT

Photoreceptor cell fate specification in vertebrates

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Cellular strategies for retinal repair by photoreceptor replacement

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Generation of a ciliary margin-like stem cell niche from self-organizing human retinal tissue

(2015) Atsushi Kuwahara et al.   Nature Communications

Efficient retina formation requires suppression of both Activin and BMP signaling pathways in pluripotent cells

(2015) K. A. Wong et al.   Biology Open

From confluent human iPS cells to self-forming neural retina and retinal pigmented epithelium

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Photoreceptor precursors derived from three-dimensional embryonic stem cell cultures integrate and mature within adult degenerate retina

(2013) Anai Gonzalez-Cordero et al.   NATURE BIOTECHNOLOGY

The BMP Inhibitor Coco Reactivates Breast Cancer Cells at Lung Metastatic Sites

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Self-Formation of Optic Cups and Storable Stratified Neural Retina from Human ESCs

(2012) Tokushige Nakano et al.   Cell Stem Cell

Antagonistic cross-regulation between Wnt and Hedgehog signalling pathways controls post-embryonic retinal proliferation

(2012) C. Borday et al.   DEVELOPMENT

Defining the Integration Capacity of Embryonic Stem Cell-Derived Photoreceptor Precursors

(2012) Emma L. West et al.   STEM CELLS

Self-organizing optic-cup morphogenesis in three-dimensional culture

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CRX ChIP-seq reveals the cis-regulatory architecture of mouse photoreceptors

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Transcriptional regulation of photoreceptor development and homeostasis in the mammalian retina

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