Ik2/TBK1 and Hook/Dynein, an adaptor complex for early endosome transport, are genetic modifiers of FTD-associated mutant CHMP2B toxicity in Drosophila

Inter-dependent Centrosomal Co-localization of the cen and ik2 cis-Natural Antisense mRNAs in Drosophila

(2020) Julie Bergalet et al.   Cell Reports

Correction: The dynein adaptor Hook2 plays essential roles in mitotic progression and cytokinesis

(2019) Devashish Dwivedi et al.   JOURNAL OF CELL BIOLOGY

The many functions of ESCRTs

(2019) Marina Vietri et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The pro-apoptotic JNK scaffold POSH/SH3RF1 mediates CHMP2BIntron5-associated toxicity in animal models of frontotemporal dementia

(2018) Ryan J H West et al.   HUMAN MOLECULAR GENETICS

Publisher Correction: The cytoplasmic dynein transport machinery and its many cargoes

(2018) Samara L. Reck-Peterson et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

RNA Binding Proteins and the Pathogenesis of Frontotemporal Lobar Degeneration

(2018) Jeffrey W. Hofmann et al.   Annual Review of Pathology-Mechanisms of Disease

Frontotemporal dementia causative CHMP2B impairs neuronal endolysosomal traffic-rescue by TMEM106B knockdown

(2018) Emma L Clayton et al.   BRAIN

Cytoplasmic dynein and early endosome transport

(2015) Xin Xiang et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

A transport and retention mechanism for the sustained distal localization of Spn-F-IKKε duringDrosophilabristle elongation

(2015) Tetsuhisa Otani et al.   DEVELOPMENT

Rab8, POSH, and TAK1 regulate synaptic growth in aDrosophilamodel of frontotemporal dementia

(2015) Ryan J.H. West et al.   JOURNAL OF CELL BIOLOGY

Haploinsufficiency of TBK1 causes familial ALS and fronto-temporal dementia

(2015) Axel Freischmidt et al.   NATURE NEUROSCIENCE

Exome sequencing in amyotrophic lateral sclerosis identifies risk genes and pathways

(2015) E. T. Cirulli et al.   SCIENCE

Ablation of retinal ciliopathy protein RPGR results in altered photoreceptor ciliary composition

(2015) Kollu N. Rao et al.   Scientific Reports

Spindle-F Is the Central Mediator of Ik2 Kinase-Dependent Dendrite Pruning in Drosophila Sensory Neurons

(2015) Tzu Lin et al.   PLoS Genetics

The Novel Zinc Finger Protein dASCIZ Regulates Mitosis in Drosophila via an Essential Role in Dynein Light-Chain Expression

(2013) O. Zaytseva et al.   GENETICS

Drosophila Oocyte Polarity and Cytoskeleton Organization Require Regulation of Ik2 Activity by Spn-F and Javelin-Like

(2013) Simha Amsalem et al.   MOLECULAR AND CELLULAR BIOLOGY

Syntaxin 13, a Genetic Modifier of Mutant CHMP2B in Frontotemporal Dementia, Is Required for Autophagosome Maturation

(2013) Yubing Lu et al.   MOLECULAR CELL

Genetic Overlap between Apparently Sporadic Motor Neuron Diseases

(2012) Marka van Blitterswijk et al.   PLoS One

Mass Spectrometry-based Proteomics Using Q Exactive, a High-performance Benchtop Quadrupole Orbitrap Mass Spectrometer

(2011) Annette Michalski et al.   MOLECULAR & CELLULAR PROTEOMICS

Novel Missense Mutation in Charged Multivesicular Body Protein 2B in a Patient With Frontotemporal Dementia

(2010) Raffaele Ferrari et al.   ALZHEIMER DISEASE & ASSOCIATED DISORDERS

Molecular Pathways of Frontotemporal Lobar Degeneration

(2010) Kristel Sleegers et al.   Annual Review of Neuroscience

Mutations in CHMP2B in Lower Motor Neuron Predominant Amyotrophic Lateral Sclerosis (ALS)

(2010) Laura E. Cox et al.   PLoS One

Autophagy defects contribute to neurodegeneration induced by dysfunctional ESCRT-III

(2009) Jin-A Lee et al.   Autophagy

Genetic screen identifies serpin5 as a regulator of the toll pathway and CHMP2B toxicity associated with frontotemporal dementia

(2009) S. T. Ahmad et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Drosophila IKK-related kinase (Ik2) and Spindle-F proteins are part of a complex that regulates cytoskeleton organization during oogenesis

(2008) Dikla Dubin-Bar et al.   BMC CELL BIOLOGY