Rab8, POSH, and TAK1 regulate synaptic growth in aDrosophilamodel of frontotemporal dementia

Alterations in microRNA-124 and AMPA receptors contribute to social behavioral deficits in frontotemporal dementia

(2014) Eduardo Gascon et al.   NATURE MEDICINE

The dynamin-binding domains of Dap160/intersectin affect bulk membrane retrieval in synapses

(2013) A. M. E. Winther et al.   JOURNAL OF CELL SCIENCE

Rab8a and Rab8b are essential for several apical transport pathways but insufficient for ciliogenesis

(2013) T. Sato et al.   JOURNAL OF CELL SCIENCE

Brain Tumor Regulates Neuromuscular Synapse Growth and Endocytosis in Drosophila by Suppressing Mad Expression

(2013) W. Shi et al.   JOURNAL OF NEUROSCIENCE

Retrograde BMP Signaling at the Synapse: A Permissive Signal for Synapse Maturation and Activity-Dependent Plasticity

(2013) B. Berke et al.   JOURNAL OF NEUROSCIENCE

Syntaxin 13, a Genetic Modifier of Mutant CHMP2B in Frontotemporal Dementia, Is Required for Autophagosome Maturation

(2013) Yubing Lu et al.   MOLECULAR CELL

BMP signaling specifies the development of a large and fast CNS synapse

(2013) Le Xiao et al.   NATURE NEUROSCIENCE

Converging Mechanisms in ALS and FTD: Disrupted RNA and Protein Homeostasis

(2013) Shuo-Chien Ling et al.   NEURON

Epsin 1 Promotes Synaptic Growth by Enhancing BMP Signal Levels in Motoneuron Nuclei

(2013) Phillip A. Vanlandingham et al.   PLoS One

The molecular basis of the frontotemporal lobar degeneration–amyotrophic lateral sclerosis spectrum

(2012) Tim van Langenhove et al.   ANNALS OF MEDICINE

Integration of a Retrograde Signal during Synapse Formation by Glia-Secreted TGF-β Ligand

(2012) Yuly Fuentes-Medel et al.   CURRENT BIOLOGY

dEHBP1controls exocytosis and recycling of Delta during asymmetric divisions

(2012) Nikolaos Giagtzoglou et al.   JOURNAL OF CELL BIOLOGY

Relay of retrograde synaptogenic signals through axonal transport of BMP receptors

(2012) R. B. Smith et al.   JOURNAL OF CELL SCIENCE

Rab8 Modulates Metabotropic Glutamate Receptor Subtype 1 Intracellular Trafficking and Signaling in a Protein Kinase C-Dependent Manner

(2012) J. L. Esseltine et al.   JOURNAL OF NEUROSCIENCE

Adar is essential for optimal presynaptic function

(2012) Carolina Maldonado et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

TGFβ signalling in context

(2012) Joan Massagué   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Genetic Overlap between Apparently Sporadic Motor Neuron Diseases

(2012) Marka van Blitterswijk et al.   PLoS One

Acute inhibition of TAK1 protects against neuronal death in cerebral ischemia

(2011) M Neubert et al.   CELL DEATH AND DIFFERENTIATION

Systematic Discovery of Rab GTPases with Synaptic Functions in Drosophila

(2011) Chih-Chiang Chan et al.   CURRENT BIOLOGY

The ESCRT Pathway

(2011) William M. Henne et al.   DEVELOPMENTAL CELL

A presynaptic endosomal trafficking pathway controls synaptic growth signaling

(2011) Avital A. Rodal et al.   JOURNAL OF CELL BIOLOGY

Expanded GGGGCC Hexanucleotide Repeat in Noncoding Region of C9ORF72 Causes Chromosome 9p-Linked FTD and ALS

(2011) Mariely DeJesus-Hernandez et al.   NEURON

A Hexanucleotide Repeat Expansion in C9ORF72 Is the Cause of Chromosome 9p21-Linked ALS-FTD

(2011) Alan E. Renton et al.   NEURON

The DISABLED protein functions in CLATHRIN-mediated synaptic vesicle endocytosis and exoendocytic coupling at the active zone

(2011) F. Kawasaki et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Oxidative stress induces overgrowth of the Drosophila neuromuscular junction

(2011) V. J. Milton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TAK1 lysine 158 is required for TGF-β-induced TRAF6-mediated Smad-independent IKK/NF-κB and JNK/AP-1 activation

(2010) Renfang Mao et al.   CELLULAR SIGNALLING

Disruption of endocytic trafficking in frontotemporal dementia with CHMP2B mutations

(2010) Hazel Urwin et al.   HUMAN MOLECULAR GENETICS

Mutations in CHMP2B in Lower Motor Neuron Predominant Amyotrophic Lateral Sclerosis (ALS)

(2010) Laura E. Cox et al.   PLoS One

Exploring the functional interaction between POSH and ALIX and the relevance to HIV-1 release

(2009) Jörg Votteler et al.   BMC BIOCHEMISTRY

POSH misexpression induces caspase-dependent cell death in Drosophila

(2009) Ashley L. Lennox et al.   DEVELOPMENTAL DYNAMICS

Genomic mapping and expression patterns of C380, OK6 and D42 enhancer trap lines in the larval nervous system of Drosophila

(2009) Subhabrata Sanyal   GENE EXPRESSION PATTERNS

Mutation withinTARDBPleads to Frontotemporal Dementia without motor neuron disease

(2009) B. Borroni et al.   HUMAN MUTATION

No evidence for cognitive dysfunction or depression in patients with mild restless legs syndrome

(2009) Erika Driver-Dunckley et al.   MOVEMENT DISORDERS

Genetic screen identifies serpin5 as a regulator of the toll pathway and CHMP2B toxicity associated with frontotemporal dementia

(2009) S. T. Ahmad et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The endocytic pathway acts downstream of Oskar in Drosophila germ plasm assembly

(2008) T. Tanaka et al.   DEVELOPMENT

Cell-Type-Specific TEV Protease Cleavage Reveals Cohesin Functions in Drosophila Neurons

(2008) Andrea Pauli et al.   DEVELOPMENTAL CELL

Inactivation of clathrin heavy chain inhibits synaptic recycling but allows bulk membrane uptake

(2008) Jaroslaw Kasprowicz et al.   JOURNAL OF CELL BIOLOGY

The type I TGF-β receptor engages TRAF6 to activate TAK1 in a receptor kinase-independent manner

(2008) Alessandro Sorrentino et al.   NATURE CELL BIOLOGY

Nervous Wreck Interacts with Thickveins and the Endocytic Machinery to Attenuate Retrograde BMP Signaling during Synaptic Growth

(2008) Kate M. O'Connor-Giles et al.   NEURON