HIF1α is not a target of 14q deletion in clear cell renal cancer

Ascorbic acid–induced TET activation mitigates adverse hydroxymethylcytosine loss in renal cell carcinoma

(2019) Niraj Shenoy et al.   JOURNAL OF CLINICAL INVESTIGATION

Tumor Cell Biodiversity Drives Microenvironmental Reprogramming in Liver Cancer

(2019) Lichun Ma et al.   CANCER CELL

Re: Targeting Renal Cell Carcinoma with a HIF-2 Antagonist

(2018) Niraj Shenoy et al.   EUROPEAN UROLOGY

A compendium of proteins that interact with HIF-1α

(2017) Gregg L. Semenza   EXPERIMENTAL CELL RESEARCH

LinkedOmics: analyzing multi-omics data within and across 32 cancer types

(2017) Suhas V Vasaikar et al.   NUCLEIC ACIDS RESEARCH

GEPIA: a web server for cancer and normal gene expression profiling and interactive analyses

(2017) Zefang Tang et al.   NUCLEIC ACIDS RESEARCH

Hypoxia inducible factor HIF-1 promotes myeloid-derived suppressor cells accumulation through ENTPD2/CD39L1 in hepatocellular carcinoma

(2017) David Kung-Chun Chiu et al.   Nature Communications

VHL Deficiency Drives Enhancer Activation of Oncogenes in Clear Cell Renal Cell Carcinoma

(2017) Xiaosai Yao et al.   Cancer Discovery

Prognostic Role of Tumor Necrosis, Microvessel Density, Vascular Endothelial Growth Factor and Hypoxia Inducible Factor-1α in Patients with Clear Cell Renal Carcinoma after Radical Nephrectomy in a Long Term Follow-up

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Sequential pathogenesis of metastatic VHL mutant clear cell renal cell carcinoma: putting it together with a translational perspective

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An Integrated Metabolic Atlas of Clear Cell Renal Cell Carcinoma

(2016) A. Ari Hakimi et al.   CANCER CELL

Targeting renal cell carcinoma with a HIF-2 antagonist

(2016) Wenfang Chen et al.   NATURE

On-target efficacy of a HIF-2α antagonist in preclinical kidney cancer models

(2016) Hyejin Cho et al.   NATURE

CRISPR-Mediated VHL Knockout Generates an Improved Model for Metastatic Renal Cell Carcinoma

(2016) Shiruyeh Schokrpur et al.   Scientific Reports

Wanderer, an interactive viewer to explore DNA methylation and gene expression data in human cancer

(2015) Anna Díez-Villanueva et al.   Epigenetics & Chromatin

The role of HIF1α in renal cell carcinoma tumorigenesis

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L-2-Hydroxyglutarate: An Epigenetic Modifier and Putative Oncometabolite in Renal Cancer

(2014) E.-H. Shim et al.   Cancer Discovery

Deletions of chromosomes 3p and 14q molecularly subclassify clear cell renal cell carcinoma

(2013) Nils Kroeger et al.   CANCER

HIF-1 mediates metabolic responses to intratumoral hypoxia and oncogenic mutations

(2013) Gregg L. Semenza   JOURNAL OF CLINICAL INVESTIGATION

TCPA: a resource for cancer functional proteomics data

(2013) Jun Li et al.   NATURE METHODS

Integrative Analysis of Complex Cancer Genomics and Clinical Profiles Using the cBioPortal

(2013) J. Gao et al.   Science Signaling

Immunoexpression Status and Prognostic Value of mTOR and Hypoxia-Induced Pathway Members in Primary and Metastatic Clear Cell Renal Cell Carcinomas

(2011) Luciana Schultz et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

Generation of a Mouse Model of Von Hippel-Lindau Kidney Disease Leading to Renal Cancers by Expression of a Constitutively Active Mutant of HIF1 

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Genetic and Functional Studies Implicate HIF1  as a 14q Kidney Cancer Suppressor Gene

(2011) C. Shen et al.   Cancer Discovery

Von Hippel-Lindau (VHL) Inactivation in Sporadic Clear Cell Renal Cancer: Associations with Germline VHL Polymorphisms and Etiologic Risk Factors

(2011) Lee E. Moore et al.   PLoS Genetics

Genome-wide identification of hypoxia-inducible factor binding sites and target genes by a probabilistic model integrating transcription-profiling data and in silico binding site prediction

(2010) Amaya Ortiz-Barahona et al.   NUCLEIC ACIDS RESEARCH

Hypoxia inducible factor-1α correlates with vascular endothelial growth factor A and C indicating worse prognosis in clear cell renal cell carcinoma

(2009) Gordana Đorđević et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics

(2009) G L Semenza   ONCOGENE

HIF-α Effects on c-Myc Distinguish Two Subtypes of Sporadic VHL-Deficient Clear Cell Renal Carcinoma

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