CRISPR-Mediated VHL Knockout Generates an Improved Model for Metastatic Renal Cell Carcinoma
Published 2016 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
CRISPR-Mediated VHL Knockout Generates an Improved Model for Metastatic Renal Cell Carcinoma
Authors
Keywords
-
Journal
Scientific Reports
Volume 6, Issue 1, Pages -
Publisher
Springer Nature
Online
2016-06-30
DOI
10.1038/srep29032
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- TScratch: a novel and simple software tool for automated analysis of monolayer wound healing assays
- (2018) Tobias Gebäck et al. BIOTECHNIQUES
- TGFβ3-mediated induction of Periostin facilitates head and neck cancer growth and is associated with metastasis
- (2016) Xing Qin et al. Scientific Reports
- Genome-wide CRISPR Screen in a Mouse Model of Tumor Growth and Metastasis
- (2015) Sidi Chen et al. CELL
- Epithelial-to-mesenchymal transition is dispensable for metastasis but induces chemoresistance in pancreatic cancer
- (2015) Xiaofeng Zheng et al. NATURE
- Epithelial-to-mesenchymal transition is not required for lung metastasis but contributes to chemoresistance
- (2015) Kari R. Fischer et al. NATURE
- In vivo genome editing using Staphylococcus aureus Cas9
- (2015) F. Ann Ran et al. NATURE
- Periostin Is a Key Niche Component for Wound Metastasis of Melanoma
- (2015) Keitaro Fukuda et al. PLoS One
- Development and Applications of CRISPR-Cas9 for Genome Engineering
- (2014) Patrick D. Hsu et al. CELL
- To "Grow" or "Go": TMEM16A Expression as a Switch between Tumor Growth and Metastasis in SCCHN
- (2014) D. J. Shiwarski et al. CLINICAL CANCER RESEARCH
- CRISPR-mediated direct mutation of cancer genes in the mouse liver
- (2014) Wen Xue et al. NATURE
- Genomic architecture and evolution of clear cell renal cell carcinomas defined by multiregion sequencing
- (2014) Marco Gerlinger et al. NATURE GENETICS
- Improved vectors and genome-wide libraries for CRISPR screening
- (2014) Neville E Sanjana et al. NATURE METHODS
- Periostin is a novel therapeutic target that predicts and regulates glioma malignancy
- (2014) Andrei M. Mikheev et al. NEURO-ONCOLOGY
- Conditional inactivation of the mouse von Hippel–Lindau tumor suppressor gene results in wide-spread hyperplastic, inflammatory and fibrotic lesions in the kidney
- (2014) T L Pritchett et al. ONCOGENE
- Bap1is essential for kidney function and cooperates withVhlin renal tumorigenesis
- (2014) Shan-Shan Wang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Modeling Spontaneous Metastatic Renal Cell Carcinoma (mRCC) in Mice Following Nephrectomy
- (2014) Amanda Tracz et al. Jove-Journal of Visualized Experiments
- Deletions of chromosomes 3p and 14q molecularly subclassify clear cell renal cell carcinoma
- (2013) Nils Kroeger et al. CANCER
- CSF1R Signaling Blockade Stanches Tumor-Infiltrating Myeloid Cells and Improves the Efficacy of Radiotherapy in Prostate Cancer
- (2013) J. Xu et al. CANCER RESEARCH
- Inhibition of CSF-1 Receptor Improves the Antitumor Efficacy of Adoptive Cell Transfer Immunotherapy
- (2013) S. Mok et al. CANCER RESEARCH
- One-Step Generation of Mice Carrying Mutations in Multiple Genes by CRISPR/Cas-Mediated Genome Engineering
- (2013) Haoyi Wang et al. CELL
- One-Step Generation of Mice Carrying Reporter and Conditional Alleles by CRISPR/Cas-Mediated Genome Engineering
- (2013) Hui Yang et al. CELL
- Combined mutation ofVhlandTrp53causes renal cysts and tumours in mice
- (2013) Joachim Albers et al. EMBO Molecular Medicine
- Genome-wide recessive genetic screening in mammalian cells with a lentiviral CRISPR-guide RNA library
- (2013) Hiroko Koike-Yusa et al. NATURE BIOTECHNOLOGY
- DNA targeting specificity of RNA-guided Cas9 nucleases
- (2013) Patrick D Hsu et al. NATURE BIOTECHNOLOGY
- Increased B Cell-Activating Factor Promotes Tumor Invasion and Metastasis in Human Pancreatic Cancer
- (2013) Mitsuhito Koizumi et al. PLoS One
- SAMSN1 Is Highly Expressed and Associated with a Poor Survival in Glioblastoma Multiforme
- (2013) Yong Yan et al. PLoS One
- Genome-Scale CRISPR-Cas9 Knockout Screening in Human Cells
- (2013) Ophir Shalem et al. SCIENCE
- Multiplex Genome Engineering Using CRISPR/Cas Systems
- (2013) L. Cong et al. SCIENCE
- Integrative Analysis of Complex Cancer Genomics and Clinical Profiles Using the cBioPortal
- (2013) J. Gao et al. Science Signaling
- Hypoxia-Dependent Modification of Collagen Networks Promotes Sarcoma Metastasis
- (2013) T. S. K. Eisinger-Mathason et al. Cancer Discovery
- A CXCL1 Paracrine Network Links Cancer Chemoresistance and Metastasis
- (2012) Swarnali Acharyya et al. CELL
- BootstRatio: A web-based statistical analysis of fold-change in qPCR and RT-qPCR data using resampling methods
- (2012) Ramon Clèries et al. COMPUTERS IN BIOLOGY AND MEDICINE
- Safety, Activity, and Immune Correlates of Anti–PD-1 Antibody in Cancer
- (2012) Suzanne L. Topalian et al. NEW ENGLAND JOURNAL OF MEDICINE
- A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity
- (2012) M. Jinek et al. SCIENCE
- The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data: Figure 1.
- (2012) Ethan Cerami et al. Cancer Discovery
- The 20th anniversary of interleukin-2 therapy: bimodal role explaining longstanding random induction of complete clinical responses
- (2012) Brendon Coventry et al. Cancer Management and Research
- EMT: A new vision of hypoxia promoting cancer progression
- (2011) Jian Jiang et al. CANCER BIOLOGY & THERAPY
- Generation of a Mouse Model of Von Hippel-Lindau Kidney Disease Leading to Renal Cancers by Expression of a Constitutively Active Mutant of HIF1
- (2011) L. Fu et al. CANCER RESEARCH
- von Hippel–Lindau disease: A clinical and scientific review
- (2011) Eamonn R Maher et al. EUROPEAN JOURNAL OF HUMAN GENETICS
- Tumor Biology and Prognostic Factors in Renal Cell Carcinoma
- (2011) D. S. Finley et al. ONCOLOGIST
- Periostin expression and epithelial-mesenchymal transition in cancer: a review and an update
- (2011) Laura Morra et al. VIRCHOWS ARCHIV
- Genetic and Functional Studies Implicate HIF1 as a 14q Kidney Cancer Suppressor Gene
- (2011) C. Shen et al. Cancer Discovery
- Von Hippel-Lindau (VHL) Inactivation in Sporadic Clear Cell Renal Cancer: Associations with Germline VHL Polymorphisms and Etiologic Risk Factors
- (2011) Lee E. Moore et al. PLoS Genetics
- NF- B-Dependent Plasticity of the Epithelial to Mesenchymal Transition Induced by Von Hippel-Lindau Inactivation in Renal Cell Carcinomas
- (2010) A. J. Pantuck et al. CANCER RESEARCH
- Direct and Differential Suppression of Myeloid-Derived Suppressor Cell Subsets by Sunitinib Is Compartmentally Constrained
- (2010) Jennifer S. Ko et al. CANCER RESEARCH
- Sunitinib Inhibition of Stat3 Induces Renal Cell Carcinoma Tumor Cell Apoptosis and Reduces Immunosuppressive Cells
- (2009) H. Xin et al. CANCER RESEARCH
- Sunitinib Mediates Reversal of Myeloid-Derived Suppressor Cell Accumulation in Renal Cell Carcinoma Patients
- (2009) J. S. Ko et al. CLINICAL CANCER RESEARCH
- The basics of epithelial-mesenchymal transition
- (2009) Raghu Kalluri et al. JOURNAL OF CLINICAL INVESTIGATION
- Suppression of Prostate Cancer Nodal and Systemic Metastasis by Blockade of the Lymphangiogenic Axis
- (2008) J. B. Burton et al. CANCER RESEARCH
- Direct regulation of TWIST by HIF-1α promotes metastasis
- (2008) Muh-Hwa Yang et al. NATURE CELL BIOLOGY
- Clinical effect and future considerations for molecularly-targeted therapy in renal cell carcinoma
- (2008) Brian I. Rini et al. UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started