Resveratrol Protects Osteoblasts Against Dexamethasone-Induced Cytotoxicity Through Activation of AMP-Activated Protein Kinase

Baicalin Ameliorates Dexamethasone-Induced Osteoporosis by Regulation of the RANK/RANKL/OPG Signaling Pathway

(2020) Ye Zhao et al.   Drug Design Development and Therapy

Resveratrol promotes osteogenesis via activating SIRT1/FoxO1 pathway in osteoporosis mice

(2020) Yixuan Jiang et al.   LIFE SCIENCES

Resveratrol Promotes in vitro Differentiation of Osteoblastic MC3T3-E1 Cells via Potentiation of the Calcineurin/NFATc1 Signaling Pathway

(2019) Y. Huang et al.   BIOCHEMISTRY-MOSCOW

Sodium hydrosulfide mitigates dexamethasone‐induced osteoblast dysfunction by interfering with mitochondrial function

(2019) Jun Ma et al.   BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY

Chlorogenic acid promotes the Nrf2/HO-1 anti-oxidative pathway by activating p21Waf1/Cip1 to resist dexamethasone-induced apoptosis in osteoblastic cells

(2019) Dandan Han et al.   FREE RADICAL BIOLOGY AND MEDICINE

MnTBAP inhibits bone loss in ovariectomized rats by reducing mitochondrial oxidative stress in osteoblasts

(2019) Xiangchang Cao et al.   JOURNAL OF BONE AND MINERAL METABOLISM

PGK1 depletion activates Nrf2 signaling to protect human osteoblasts from dexamethasone

(2019) Jinqian Liang et al.   Cell Death & Disease

The Role and Mechanism of SIRT1 in Resveratrol-regulated Osteoblast Autophagy in Osteoporosis Rats

(2019) Xuhao Yang et al.   Scientific Reports

Activation of AMP-activated protein kinase by compound 991 protects osteoblasts from dexamethasone

(2018) Yong-yi Xu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Dexamethasone-induced immunosuppression: mechanisms and implications for immunotherapy

(2018) Amber J. Giles et al.   Journal for ImmunoTherapy of Cancer

Osteoprotegerin inhibit osteoclast differentiation and bone resorption by enhancing autophagy via AMPK/mTOR/p70S6K signaling pathway in vitro

(2018) Xishuai Tong et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Effects of resveratrol on bone health in type 2 diabetic patients. A double-blind randomized-controlled trial

(2018) Simona Bo et al.   Nutrition & Diabetes

Osteoblast autophagy in glucocorticoid-induced osteoporosis

(2018) Lufei Wang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Energy Metabolism of the Osteoblast: Implications for Osteoporosis

(2017) Wen-Chih Lee et al.   ENDOCRINE REVIEWS

Local intra-articular injection of resveratrol delays cartilage degeneration in C57BL/6 mice by inducing autophagy via AMPK/mTOR pathway

(2017) Na Qin et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Resveratrol suppresses the alveolar bone resorption induced by artificial trauma from occlusion in mice

(2017) Y Matsuda et al.   ORAL DISEASES

The Flavonoid 7,4′-Dihydroxyflavone Prevents Dexamethasone Paradoxical Adverse Effect on Eotaxin Production by Human Fibroblasts

(2017) Changda Liu et al.   PHYTOTHERAPY RESEARCH

Resveratrol prevents alveolar bone loss in an experimental rat model of periodontitis

(2016) Govinda Bhattarai et al.   Acta Biomaterialia

HIF-1α Promotes Glutamine-Mediated Redox Homeostasis and Glycogen-Dependent Bioenergetics to Support Postimplantation Bone Cell Survival

(2016) Steve Stegen et al.   Cell Metabolism

Role of Nrf2/HO-1 system in development, oxidative stress response and diseases: an evolutionarily conserved mechanism

(2016) Agnieszka Loboda et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

AMPK promotes osteogenesis and inhibits adipogenesis through AMPK-Gfi1-OPN axis

(2016) Yu-gang Wang et al.   CELLULAR SIGNALLING

Long-term side effects of glucocorticoids

(2016) Merih Oray et al.   Expert Opinion On Drug Safety

Curcumin protects human adipose-derived mesenchymal stem cells against oxidative stress-induced inhibition of osteogenesis

(2016) Nan Wang et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Nrf2 regulates ROS production by mitochondria and NADPH oxidase

(2015) Stjepana Kovac et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Resveratrol supplementation affects bone acquisition and osteoporosis: Pre-clinical evidence toward translational diet therapy

(2015) Janet C. Tou   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

CTRP3 acts as a negative regulator of osteoclastogenesis through AMPK-c-Fos-NFATc1 signaling in vitro and RANKL-induced calvarial bone destruction in vivo

(2015) Ju-Young Kim et al.   BONE

AMP-activated protein kinase (AMPK) activity negatively regulates chondrogenic differentiation

(2015) Kenjiro Bandow et al.   BONE

Carfilzomib, Lenalidomide, and Dexamethasone for Relapsed Multiple Myeloma

(2015) A. Keith Stewart et al.   NEW ENGLAND JOURNAL OF MEDICINE

Glucocorticoid (dexamethasone)-induced metabolome changes in healthy males suggest prediction of response and side effects

(2015) Natalie Bordag et al.   Scientific Reports

Activation of AMPK participates hydrogen sulfide-induced cyto-protective effect against dexamethasone in osteoblastic MC3T3-E1 cells

(2014) Ming Yang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Mitochondrial Complex I Activity Suppresses Inflammation and Enhances Bone Resorption by Shifting Macrophage-Osteoclast Polarization

(2014) Zixue Jin et al.   Cell Metabolism

Fisetin prevents fluoride- and dexamethasone-induced oxidative damage in osteoblast and hippocampal cells

(2011) Iwona Inkielewicz-Stepniak et al.   FOOD AND CHEMICAL TOXICOLOGY

AMP-activated protein kinase (AMPK) activation regulates in vitro bone formation and bone mass

(2010) M. Shah et al.   BONE

Sirtuin 3, a New Target of PGC-1α, Plays an Important Role in the Suppression of ROS and Mitochondrial Biogenesis

(2010) Xingxing Kong et al.   PLoS One

Coordination of PGC-1β and iron uptake in mitochondrial biogenesis and osteoclast activation

(2009) Kiyo-aki Ishii et al.   NATURE MEDICINE

Functions of RANKL/RANK/OPG in bone modeling and remodeling

(2008) Brendan F. Boyce et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Regulation of bone development and maintenance by Runx2

(2007) Toshihisa Komori   Frontiers in Bioscience-Landmark