WNT11-FZD7-DAAM1 signalling supports tumour initiating abilities and melanoma amoeboid invasion

Myosin II Reactivation and Cytoskeletal Remodeling as a Hallmark and a Vulnerability in Melanoma Therapy Resistance

(2020) Jose L. Orgaz et al.   CANCER CELL

Cancer Burden Is Controlled by Mural Cell-β3-Integrin Regulated Crosstalk with Tumor Cells

(2020) Ping-Pui Wong et al.   CELL

Regional Activation of Myosin II in Cancer Cells Drives Tumor Progression via a Secretory Cross-Talk with the Immune Microenvironment

(2019) Mirella Georgouli et al.   CELL

SMAD signaling promotes melanoma metastasis independently of phenotype switching

(2019) Eylul Tuncer et al.   JOURNAL OF CLINICAL INVESTIGATION

Melanoma plasticity and phenotypic diversity: therapeutic barriers and opportunities

(2019) Florian Rambow et al.   GENES & DEVELOPMENT

ROCK2 Confers Acquired Gemcitabine Resistance in Pancreatic Cancer Cells by Upregulating Transcription Factor ZEB1

(2019) Yang Zhou et al.   Cancers

Toward Minimal Residual Disease-Directed Therapy in Melanoma

(2018) Florian Rambow et al.   CELL

Regulation of neural crest development by the formin family protein Daam1

(2018) Olga Ossipova et al.   GENESIS

Supervillin promotes epithelial-mesenchymal transition and metastasis of hepatocellular carcinoma in hypoxia via activation of the RhoA/ROCK-ERK/p38 pathway

(2018) Xueran Chen et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Stem cell functionality is microenvironmentally defined during tumour expansion and therapy response in colon cancer

(2018) Kristiaan J. Lenos et al.   NATURE CELL BIOLOGY

Characterization of stem cell and cancer stem cell populations in ovary and ovarian tumors

(2018) Seema C. Parte et al.   Journal of Ovarian Research

Epithelial-to-mesenchymal transition in cancer: complexity and opportunities

(2018) Yun Zhang et al.   Frontiers of Medicine

Cancer stem cells revisited

(2017) Eduard Batlle et al.   NATURE MEDICINE

TGFΒ-induced transcription in cancer

(2017) Gaia Cantelli et al.   SEMINARS IN CANCER BIOLOGY

Intratumor and Intertumor Heterogeneity in Melanoma

(2017) Tomasz M. Grzywa et al.   Translational Oncology

Actomyosin drives cancer cell nuclear dysmorphia and threatens genome stability

(2017) Tohru Takaki et al.   Nature Communications

QuPath: Open source software for digital pathology image analysis

(2017) Peter Bankhead et al.   Scientific Reports

Ki-67 is required for maintenance of cancer stem cells but not cell proliferation

(2016) Justin Cidado et al.   Oncotarget

Rho-associated kinase (ROCK) function is essential for cell cycle progression, senescence and tumorigenesis

(2016) Sandra Kümper et al.   eLife

Crosstalk in skin: melanocytes, keratinocytes, stem cells, and melanoma

(2016) Joshua X. Wang et al.   Journal of Cell Communication and Signaling

TGF-β-Induced Transcription Sustains Amoeboid Melanoma Migration and Dissemination

(2015) Gaia Cantelli et al.   CURRENT BIOLOGY

Targeting ALDH1 to decrease tumorigenicity, growth and metastasis of human melanoma

(2015) Lili Yue et al.   MELANOMA RESEARCH

Oxidative stress inhibits distant metastasis by human melanoma cells

(2015) Elena Piskounova et al.   NATURE

Antioxidants can increase melanoma metastasis in mice

(2015) Kristell Le Gal et al.   Science Translational Medicine

Decoding the regulatory landscape of melanoma reveals TEADS as regulators of the invasive cell state

(2015) Annelien Verfaillie et al.   Nature Communications

Mesenchymal Cancer Cell-Stroma Crosstalk Promotes Niche Activation, Epithelial Reversion, and Metastatic Colonization

(2015) Yaiza del Pozo Martin et al.   Cell Reports

Developmental pathways activated in melanocytes and melanoma

(2014) Jianglan Liu et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Phenotype Switching: Tumor Cell Plasticity as a Resistance Mechanism and Target for Therapy

(2014) K. Kemper et al.   CANCER RESEARCH

Molecular mechanisms of epithelial–mesenchymal transition

(2014) Samy Lamouille et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

FZD7 drives in vitro aggressiveness in Stem-A subtype of ovarian cancer via regulation of non-canonical Wnt/PCP pathway

(2014) M Asad et al.   Cell Death & Disease

Diverse matrix metalloproteinase functions regulate cancer amoeboid migration

(2014) Jose L. Orgaz et al.   Nature Communications

Melanoma Cells Revive an Embryonic Transcriptional Network to Dictate Phenotypic Heterogeneity

(2014) Niels Vandamme et al.   Frontiers in Oncology

Overcoming Intrinsic Multidrug Resistance in Melanoma by Blocking the Mitochondrial Respiratory Chain of Slow-Cycling JARID1Bhigh Cells

(2013) Alexander Roesch et al.   CANCER CELL

The neural crest

(2013) R. Mayor et al.   DEVELOPMENT

Matrix geometry determines optimal cancer cell migration strategy and modulates response to interventions

(2013) Melda Tozluoğlu et al.   NATURE CELL BIOLOGY

Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration

(2012) Valbona Luga et al.   CELL

Planar Cell Polarity Links Axes of Spatial Dynamics in Neural-Tube Closure

(2012) Tamako Nishimura et al.   CELL

Matrix-Bound PAI-1 Supports Cell Blebbing via RhoA/ROCK1 Signaling

(2012) Amandine Cartier-Michaud et al.   PLoS One

Wnt/Ca2+ signaling pathway: a brief overview

(2011) Antara De   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

ROCK and JAK1 Signaling Cooperate to Control Actomyosin Contractility in Tumor Cells and Stroma

(2011) Victoria Sanz-Moreno et al.   CANCER CELL

Aldehyde dehydrogenase: Its role as a cancer stem cell marker comes down to the specific isoform

(2011) Paola Marcato et al.   CELL CYCLE

Neural crest specification by noncanonical Wnt signaling and PAR-1

(2011) O. Ossipova et al.   DEVELOPMENT

Prognostic Significance of Mitotic Rate in Localized Primary Cutaneous Melanoma: An Analysis of Patients in the Multi-Institutional American Joint Committee on Cancer Melanoma Staging Database

(2011) John F. Thompson et al.   JOURNAL OF CLINICAL ONCOLOGY

Integrative Genome Comparison of Primary and Metastatic Melanomas

(2010) Omar Kabbarah et al.   PLoS One

ELDA: Extreme limiting dilution analysis for comparing depleted and enriched populations in stem cell and other assays

(2009) Yifang Hu et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1

(2009) David A. Barbie et al.   NATURE

Myocardin-related transcription factors and SRF are required for cytoskeletal dynamics and experimental metastasis

(2009) Souhila Medjkane et al.   NATURE CELL BIOLOGY

The gene expression profiles of primary and metastatic melanoma yields a transition point of tumor progression and metastasis

(2008) Adam I Riker et al.   BMC Medical Genomics

In vivo Switching of Human Melanoma Cells between Proliferative and Invasive States

(2008) K. S. Hoek et al.   CANCER RESEARCH

Rac Activation and Inactivation Control Plasticity of Tumor Cell Movement

(2008) Victoria Sanz-Moreno et al.   CELL

Directional migration of neural crest cells in vivo is regulated by Syndecan-4/Rac1 and non-canonical Wnt signaling/RhoA

(2008) H. K. Matthews et al.   DEVELOPMENT

Imaging amoeboid cancer cell motilityin vivo

(2008) S. PINNER et al.   JOURNAL OF MICROSCOPY

Gene Expression Changes in an Animal Melanoma Model Correlate with Aggressiveness of Human Melanoma Metastases

(2008) L. Xu et al.   MOLECULAR CANCER RESEARCH

Contact inhibition of locomotion in vivo controls neural crest directional migration

(2008) Carlos Carmona-Fontaine et al.   NATURE

Efficient tumour formation by single human melanoma cells

(2008) Elsa Quintana et al.   NATURE