Characterization and mitigation of gene expression burden in mammalian cells
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Title
Characterization and mitigation of gene expression burden in mammalian cells
Authors
Keywords
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Journal
Nature Communications
Volume 11, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2020-09-15
DOI
10.1038/s41467-020-18392-x
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- (2017) Yili Qian et al. ACS Synthetic Biology
- Overloaded and stressed: whole-cell considerations for bacterial synthetic biology
- (2016) Olivier Borkowski et al. CURRENT OPINION IN MICROBIOLOGY
- A multiplexed miRNA and transgene expression platform for simultaneous repression and expression of protein coding sequences
- (2016) Attila A. Seyhan Molecular BioSystems
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- (2016) M. Xie et al. SCIENCE
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- (2013) Stefan L. Ameres et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
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- (2012) Yannick Rondelez PHYSICAL REVIEW LETTERS
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- (2011) L. Bleris et al. Molecular Systems Biology
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