Paeonol Inhibits IL-1β-Induced Inflammation via PI3K/Akt/NF-κB Pathways: In Vivo and Vitro Studies

Paeonol promotes microRNA-126 expression to inhibit monocyte adhesion to ox-LDL-injured vascular endothelial cells and block the activation of the PI3K/Akt/NF-κB pathway

(2016) Xusheng Yuan et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

PPARγ deficiency results in severe, accelerated osteoarthritis associated with aberrant mTOR signalling in the articular cartilage

(2015) Faezeh Vasheghani et al.   ANNALS OF THE RHEUMATIC DISEASES

Anti-inflammatory effects of farrerol on IL-1β-stimulated human osteoarthritis chondrocytes

(2015) Hongfei Zhang et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Echinocystic Acid Inhibits IL-1β-Induced COX-2 and iNOS Expression in Human Osteoarthritis Chondrocytes

(2015) Zhiqiang Ma et al.   INFLAMMATION

H-RN, a novel antiangiogenic peptide derived from hepatocyte growth factor inhibits inflammation in vitro and in vivo through PI3K/AKT/IKK/NF-κB signal pathway

(2014) Lili Wang et al.   BIOCHEMICAL PHARMACOLOGY

Recent Progress in Osteoarthritis Research

(2014) Jie Shen et al.   JOURNAL OF THE AMERICAN ACADEMY OF ORTHOPAEDIC SURGEONS

Matrix Metalloproteases and Tissue Inhibitors of Metalloproteinases in Medial Plica and Pannus-like Tissue Contribute to Knee Osteoarthritis Progression

(2013) Chih-Chang Yang et al.   PLoS One

Effect of Paeonol on Antioxidant and Immune Regulatory Activity in Hepatocellular Carcinoma Rats

(2012) Bendong Chen et al.   MOLECULES

Paeonol from Hippocampus kuda Bleeler suppressed the neuro-inflammatory responses in vitro via NF-κB and MAPK signaling pathways

(2012) S.W.A. Himaya et al.   TOXICOLOGY IN VITRO

Anti-arthritic effects of chlorogenic acid in interleukin-1β-induced rabbit chondrocytes and a rabbit osteoarthritis model

(2010) Wei-Ping Chen et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Inhibition of LPS-Induced iNOS, COX-2 and Inflammatory Mediator Expression by Paeonol through the MAPKs Inactivation in RAW 264.7 Cells

(2009) Hee-Sung Chae et al.   AMERICAN JOURNAL OF CHINESE MEDICINE