LINC01106 drives colorectal cancer growth and stemness through a positive feedback loop to regulate the Gli family factors

LncRNA BCAR4, targeting to miR-665/STAT3 signaling, maintains cancer stem cells stemness and promotes tumorigenicity in colorectal cancer

(2019) Shurui Ouyang et al.   Cancer Cell International

LINC01354 interacting with hnRNP-D contributes to the proliferation and metastasis in colorectal cancer through activating Wnt/β-catenin signaling pathway

(2019) Jing Li et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

SNHG15 is a bifunctional MYC-regulated noncoding locus encoding a lncRNA that promotes cell proliferation, invasion and drug resistance in colorectal cancer by interacting with AIF

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Functional role of long non-coding RNA CASC19/miR-140-5p/CEMIP axis in colorectal cancer progression in vitro

(2019) Xiao-Dong Wang et al.   WORLD JOURNAL OF GASTROENTEROLOGY

USF1-induced upregulation of LINC01048 promotes cell proliferation and apoptosis in cutaneous squamous cell carcinoma by binding to TAF15 to transcriptionally activate YAP1

(2019) Lezi Chen et al.   Cell Death & Disease

RUNX3 suppresses metastasis and stemness by inhibiting Hedgehog signaling in colorectal cancer

(2019) Bo Ram Kim et al.   CELL DEATH AND DIFFERENTIATION

LncRNA CASC9 interacts with CPSF3 to regulate TGF-β signaling in colorectal cancer

(2019) Kaili Luo et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Fused in sarcoma silences HIV gene transcription and maintains viral latency through suppressing AFF4 gene activation

(2019) Simona Krasnopolsky et al.   Retrovirology

TSPAN8 promotes cancer cell stemness via activation of sonic Hedgehog signaling

(2019) Rongxuan Zhu et al.   Nature Communications

FOXM1-Mediated LINC-ROR Regulates the Proliferation and Sensitivity to Sorafenib in Hepatocellular Carcinoma

(2019) Yingru Zhi et al.   Molecular Therapy-Nucleic Acids

A ceRNA circuitry involving the long noncoding RNA Klhl14-AS, Pax8 and Bcl2 drives thyroid carcinogenesis

(2019) Sara C Credendino et al.   CANCER RESEARCH

LINC00265 promotes colorectal tumorigenesis via ZMIZ2 and USP7-mediated stabilization of β-catenin

(2019) Yahui Zhu et al.   CELL DEATH AND DIFFERENTIATION

Long noncoding RNA SMAD5-AS1 acts as a microRNA-106a-5p sponge to promote epithelial mesenchymal transition in nasopharyngeal carcinoma

(2019) Ying-Juan Zheng et al.   FASEB JOURNAL

LINC01123, a c-Myc-activated long non-coding RNA, promotes proliferation and aerobic glycolysis of non-small cell lung cancer through miR-199a-5p/c-Myc axis

(2019) Qian Hua et al.   Journal of Hematology & Oncology

Long noncoding RNA GSTM3TV2 upregulates LAT2 and OLR1 by competitively sponging let-7 to promote gemcitabine resistance in pancreatic cancer

(2019) Guangbing Xiong et al.   Journal of Hematology & Oncology

Linc00173 promotes chemoresistance and progression of small cell lung cancer by sponging miR-218 to regulate Etk expression

(2019) Fanrui Zeng et al.   ONCOGENE

Long non-coding RNA SNHG3 promotes progression of gastric cancer by regulating neighboring MED18 gene methylation

(2019) Yi Xuan et al.   Cell Death & Disease

Profiling the lncRNA-miRNA-mRNA ceRNA network to reveal potential crosstalk between inflammatory bowel disease and colorectal cancer

(2019) Fangfang Sun et al.   PeerJ

FUS-mediated regulation of acetylcholine receptor transcription at neuromuscular junctions is compromised in amyotrophic lateral sclerosis

(2019) Gina Picchiarelli et al.   NATURE NEUROSCIENCE

Circular RNA circ0005276 promotes the proliferation and migration of prostate cancer cells by interacting with FUS to transcriptionally activate XIAP

(2019) Yang Feng et al.   Cell Death & Disease

LncRNA FLVCR1-AS1 acts as miR-513c sponge to modulate cancer cell proliferation, migration, and invasion in hepatocellular carcinoma

(2018) Kunsong Zhang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Roles for Interleukin 17 and Adaptive Immunity in Pathogenesis of Colorectal Cancer

(2018) Christopher G. Hurtado et al.   GASTROENTEROLOGY

MicroRNA-324-5p regulates stemness, pathogenesis and sensitivity to bortezomib in multiple myeloma cells by targeting hedgehog signaling

(2017) Bo Tang et al.   INTERNATIONAL JOURNAL OF CANCER

Long noncoding AGAP2-AS1 is activated by SP1 and promotes cell proliferation and invasion in gastric cancer

(2017) Fuzhen Qi et al.   Journal of Hematology & Oncology

STAT3-mediated upregulation of lncRNA HOXD-AS1 as a ceRNA facilitates liver cancer metastasis by regulating SOX4

(2017) Hui Wang et al.   Molecular Cancer

Colorectal cancer heterogeneity and targeted therapy: Clinical implications, challenges and solutions for treatment resistance

(2017) Zhenhua Zhai et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Long non-coding RNA UICLM promotes colorectal cancer liver metastasis by acting as a ceRNA for microRNA-215 to regulate ZEB2 expression

(2017) Dong-liang Chen et al.   Theranostics

The Prognostic Significance of the Hedgehog Signaling Pathway in Colorectal Cancer

(2016) Vassilis Papadopoulos et al.   Clinical Colorectal Cancer

Upregulated long non-coding RNA AGAP2-AS1 represses LATS2 and KLF2 expression through interacting with EZH2 and LSD1 in non-small-cell lung cancer cells

(2016) W Li et al.   Cell Death & Disease

LncRNA GClnc1 Promotes Gastric Carcinogenesis and May Act as a Modular Scaffold of WDR5 and KAT2A Complexes to Specify the Histone Modification Pattern

(2016) T.-T. Sun et al.   Cancer Discovery

miRNA-144 suppresses proliferation and migration of colorectal cancer cells through GSPT1

(2015) Ruilin Xiao et al.   BIOMEDICINE & PHARMACOTHERAPY

Colorectal cancer

(2015) Herb Brody   NATURE

FUS functions in coupling transcription to splicing by mediating an interaction between RNAP II and U1 snRNP

(2015) Yong Yu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Self-assembled FUS binds active chromatin and regulates gene transcription

(2014) Liuqing Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genome Regulation by Long Noncoding RNAs

(2012) John L. Rinn et al.   Annual Review of Biochemistry

The RNA Pol II Elongation Factor Ell3 Marks Enhancers in ES Cells and Primes Future Gene Activation

(2012) Chengqi Lin et al.   CELL

Gli Proteins in Development and Disease

(2011) Chi-chung Hui et al.   Annual Review of Cell and Developmental Biology

Long Noncoding RNA HOTAIR Regulates Polycomb-Dependent Chromatin Modification and Is Associated with Poor Prognosis in Colorectal Cancers

(2011) R. Kogo et al.   CANCER RESEARCH

A ceRNA Hypothesis: The Rosetta Stone of a Hidden RNA Language?

(2011) Leonardo Salmena et al.   CELL

Molecular Mechanisms of Long Noncoding RNAs

(2011) Kevin C. Wang et al.   MOLECULAR CELL

Colorectal cancer molecular biology moves into clinical practice

(2010) C. C. Pritchard et al.   GUT

Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008

(2010) Jacques Ferlay et al.   INTERNATIONAL JOURNAL OF CANCER

Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis

(2010) Rajnish A. Gupta et al.   NATURE

Long Noncoding RNA as Modular Scaffold of Histone Modification Complexes

(2010) M.-C. Tsai et al.   SCIENCE

Many roads to maturity: microRNA biogenesis pathways and their regulation

(2009) Julia Winter et al.   NATURE CELL BIOLOGY