Sigma 54-Regulated Transcription Is Associated with Membrane Reorganization and Type III Secretion Effectors during Conversion to Infectious Forms of Chlamydia trachomatis

FRAEM-mediated gene deletion indicates a requirement for Chlamydia trachomatis Tarp during in vivo infectivity and reveals a specific role for the C-terminus during cellular invasion

(2020) Susmita Ghosh et al.   INFECTION AND IMMUNITY

Chlamydia trachomatis CT229 Subverts Rab GTPase-Dependent CCV Trafficking Pathways to Promote Chlamydial Infection

(2019) Robert Faris et al.   Cell Reports

Mechanisms of σ54-Dependent Transcription Initiation and Regulation

(2019) Amy E. Danson et al.   JOURNAL OF MOLECULAR BIOLOGY

Transcription of Bacterial Chromatin

(2019) Beth A. Shen et al.   JOURNAL OF MOLECULAR BIOLOGY

Transposon Mutagenesis in Chlamydia trachomatis Identifies CT339 as a ComEC Homolog Important for DNA Uptake and Lateral Gene Transfer

(2019) Scott D. LaBrie et al.   mBio

Structural and ligand binding analyses of the periplasmic sensor domain of RsbU in Chlamydia trachomatis support a role in TCA cycle regulation

(2019) Katelyn R. Soules et al.   MOLECULAR MICROBIOLOGY

The Loss of Expression of a Single Type 3 Effector (CT622) Strongly Reduces Chlamydia trachomatis Infectivity and Growth

(2018) Mathilde M. Cossé et al.   Frontiers in Cellular and Infection Microbiology

Direct visualization of the expression and localization of chlamydial effector proteins within infected host cells

(2018) Xiaogang Wang et al.   Pathogens and Disease

The Human Centrosomal Protein CCDC146 Binds Chlamydia trachomatis Inclusion Membrane Protein CT288 and Is Recruited to the Periphery of the Chlamydia-Containing Vacuole

(2018) Filipe Almeida et al.   Frontiers in Cellular and Infection Microbiology

The Chlamydia trachomatis type III secretion substrates CT142, CT143, and CT144 are secreted into the lumen of the inclusion

(2017) Maria da Cunha et al.   PLoS One

Absence of Specific Chlamydia trachomatis Inclusion Membrane Proteins Triggers Premature Inclusion Membrane Lysis and Host Cell Death

(2017) Mary M. Weber et al.   Cell Reports

A Laboratory Methodology for Dual RNA-Sequencing of Bacteria and their Host Cells In Vitro

(2017) James W. Marsh et al.   Frontiers in Microbiology

Chlamydia trachomatis ChxR is a transcriptional regulator of virulence factors that function in in vivo host–pathogen interactions

(2017) Chunfu Yang et al.   Pathogens and Disease

Chlamydia cell biology and pathogenesis

(2016) Cherilyn Elwell et al.   NATURE REVIEWS MICROBIOLOGY

The DUF582 Proteins of Chlamydia trachomatis Bind to Components of the ESCRT Machinery, Which Is Dispensable for Bacterial Growth In vitro

(2016) François Vromman et al.   Frontiers in Cellular and Infection Microbiology

Global Mapping of the Inc-Human Interactome Reveals that Retromer Restricts Chlamydia Infection

(2015) Kathleen M. Mirrashidi et al.   Cell Host & Microbe

Expression and Localization of Predicted Inclusion Membrane Proteins in Chlamydia trachomatis

(2015) Mary M. Weber et al.   INFECTION AND IMMUNITY

Regulation of Chlamydia Gene Expression by Tandem Promoters with Different Temporal Patterns

(2015) Christopher J. Rosario et al.   JOURNAL OF BACTERIOLOGY

Transcriptional regulation of theChlamydiaheat shock stress response in an intracellular infection

(2015) Brett R. Hanson et al.   MOLECULAR MICROBIOLOGY

Functional analysis of three topoisomerases that regulate DNA supercoiling levels inChlamydia

(2015) Emilie Orillard et al.   MOLECULAR MICROBIOLOGY

Hypothetical protein CT398 (CdsZ) interacts with σ54 (RpoN)-holoenzyme and the type III secretion export apparatus in Chlamydia trachomatis

(2015) Michael L. Barta et al.   PROTEIN SCIENCE

Rapid and efficient genome-wide characterization of Xanthomonas TAL effector genes

(2015) Yan-Hua Yu et al.   Scientific Reports

Identification of type III secretion substrates of Chlamydia trachomatis using Yersinia enterocolitica as a heterologous system

(2014) Maria da Cunha et al.   BMC MICROBIOLOGY

The Chlamydia trachomatis Type III Secretion Chaperone Slc1 Engages Multiple Early Effectors, Including TepP, a Tyrosine-phosphorylated Protein Required for the Recruitment of CrkI-II to Nascent Inclusions and Innate Immune Signaling

(2014) Yi-Shan Chen et al.   PLoS Pathogens

Reconceptualizing the chlamydial inclusion as a pathogen-specified parasitic organelle: an expanded role for Inc proteins

(2014) Elizabeth R. Moore et al.   Frontiers in Cellular and Infection Microbiology

Use of a promiscuous, constitutively-active bacterial enhancer-binding protein to define the σ54 (RpoN) regulon of Salmonella Typhimurium LT2

(2013) David J Samuels et al.   BMC GENOMICS

Chlamydia trachomatis GlgA Is Secreted into Host Cell Cytoplasm

(2013) Chunxue Lu et al.   PLoS One

Conditional Gene Expression in Chlamydia trachomatis Using the Tet System

(2013) Jason Wickstrum et al.   PLoS One

Simultaneous Transcriptional Profiling of Bacteria and Their Host Cells

(2013) Michael S. Humphrys et al.   PLoS One

Genus-optimized strategy for the identification of chlamydial type III secretion substrates

(2013) Kelley M. Hovis et al.   Pathogens and Disease

Differential Effects of DNA Supercoiling on Chlamydia Early Promoters Correlate with Expression Patterns in Midcycle

(2012) E. Cheng et al.   JOURNAL OF BACTERIOLOGY

High-Throughput Droplet Digital PCR System for Absolute Quantitation of DNA Copy Number

(2011) Benjamin J. Hindson et al.   ANALYTICAL CHEMISTRY

Comparative analyses imply that the enigmatic sigma factor 54 is a central controller of the bacterial exterior

(2011) Christof Francke et al.   BMC GENOMICS

The Chlamydial Type III Secretion Mechanism: Revealing Cracks in a Tough Nut

(2011) Helen Jennifer Betts-Hampikian et al.   Frontiers in Microbiology

Identification of a Family of Effectors Secreted by the Type III Secretion System That Are Conserved in Pathogenic Chlamydiae

(2010) Sandra Muschiol et al.   INFECTION AND IMMUNITY

Identification of Chlamydia trachomatis Outer Membrane Complex Proteins by Differential Proteomics

(2010) X. Liu et al.   JOURNAL OF BACTERIOLOGY

Identification ofChlamydia trachomatisCT621, a protein delivered through the type III secretion system to the host cell cytoplasm and nucleus

(2009) Anne-Sofie Hobolt-Pedersen et al.   FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY

Evidence that CT694 is a novelChlamydia trachomatisT3S substrate capable of functioning during invasion or early cycle development

(2009) S. Hower et al.   MOLECULAR MICROBIOLOGY

Deep sequencing-based discovery of the Chlamydia trachomatis transcriptome

(2009) Marco Albrecht et al.   NUCLEIC ACIDS RESEARCH

The Chlamydia Type III Secretion System C-ring Engages a Chaperone-Effector Protein Complex

(2009) Kris E. Spaeth et al.   PLoS Pathogens

Chlamydia effector proteins and new insights into chlamydial cellular microbiology

(2008) Raphael H Valdivia   CURRENT OPINION IN MICROBIOLOGY

Characterization of Fifty Putative Inclusion Membrane Proteins Encoded in the Chlamydia trachomatis Genome

(2008) Z. Li et al.   INFECTION AND IMMUNITY

Pmp-Like Proteins Pls1 and Pls2 Are Secreted into the Lumen of the Chlamydia trachomatis Inclusion

(2008) I. Jorgensen et al.   INFECTION AND IMMUNITY

DNA Supercoiling-Dependent Gene Regulation in Chlamydia

(2008) E. Niehus et al.   JOURNAL OF BACTERIOLOGY

The AAA+ superfamily of functionally diverse proteins

(2008) Jamie Snider et al.   GENOME BIOLOGY