- Home
- Publications
- Publication Search
- Publication Details
Title
Restoring Regulatory T Cells in Type 1 Diabetes
Authors
Keywords
Regulatory T cells (Tregs), Type 1 diabetes, Nonobese diabetic (NOD) mice, IL-2, CTLA-4, Therapy
Journal
Current Diabetes Reports
Volume 16, Issue 11, Pages -
Publisher
Springer Nature
Online
2016-09-23
DOI
10.1007/s11892-016-0807-6
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- A pilot study of operational tolerance with a regulatory T-cell-based cell therapy in living donor liver transplantation
- (2016) Satoru Todo et al. HEPATOLOGY
- Dendritic Cells Coordinate the Development and Homeostasis of Organ-Specific Regulatory T Cells
- (2016) Daniel S. Leventhal et al. IMMUNITY
- Hydrophobic CDR3 residues promote the development of self-reactive T cells
- (2016) Brian D Stadinski et al. NATURE IMMUNOLOGY
- Pathogenic CD4 T cells in type 1 diabetes recognize epitopes formed by peptide fusion
- (2016) T. Delong et al. SCIENCE
- Type 1 diabetes vaccine candidates promote human Foxp3+Treg induction in humanized mice
- (2016) Isabelle Serr et al. Nature Communications
- Nanoparticle-based autoimmune disease therapy
- (2015) Pau Serra et al. CLINICAL IMMUNOLOGY
- Therapeutic Window of Interleukin-2 for Autoimmune Diseases: Figure 1
- (2015) Qizhi Tang DIABETES
- Selective IL-2 Responsiveness of Regulatory T Cells Through Multiple Intrinsic Mechanisms Supports the Use of Low-Dose IL-2 Therapy in Type 1 Diabetes
- (2015) Aixin Yu et al. DIABETES
- Alefacept provides sustained clinical and immunological effects in new-onset type 1 diabetes patients
- (2015) Mark R. Rigby et al. JOURNAL OF CLINICAL INVESTIGATION
- Combination Therapy Using IL-2/IL-2 Monoclonal Antibody Complexes, Rapamycin, and Islet Autoantigen Peptides Increases Regulatory T Cell Frequency and Protects against Spontaneous and Induced Type 1 Diabetes in Nonobese Diabetic Mice
- (2015) J. N. Manirarora et al. JOURNAL OF IMMUNOLOGY
- Dendritic cell SIRT1–HIF1α axis programs the differentiation of CD4+T cells through IL-12 and TGF-β1
- (2015) Guangwei Liu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Type 1 diabetes immunotherapy using polyclonal regulatory T cells
- (2015) Jeffrey A. Bluestone et al. Science Translational Medicine
- Protocol of the adaptive study of IL-2 dose frequency on regulatory T cells in type 1 diabetes (DILfrequency): a mechanistic, non-randomised, repeat dose, open-label, response-adaptive study
- (2015) Lucy A Truman et al. BMJ Open
- Safety profile of intravenous and subcutaneous siplizumab, an anti-CD2 monoclonal antibody, for the treatment of plaque psoriasis: results of two randomized, double-blind, placebo-controlled studies
- (2015) Richard G. Langley et al. INTERNATIONAL JOURNAL OF DERMATOLOGY
- Antigen Presentation in the Autoimmune Diabetes of the NOD Mouse
- (2014) Emil R. Unanue Annual Review of Immunology
- Interleukin-5-producing group 2 innate lymphoid cells control eosinophilia induced by interleukin-2 therapy
- (2014) F. Van Gool et al. BLOOD
- Therapy of type 1 diabetes with CD4+CD25highCD127-regulatory T cells prolongs survival of pancreatic islets — Results of one year follow-up
- (2014) Natalia Marek-Trzonkowska et al. CLINICAL IMMUNOLOGY
- Regulatory T Cells Control Antigen-Specific Expansion of Tfh Cell Number and Humoral Immune Responses via the Coreceptor CTLA-4
- (2014) James Badger Wing et al. IMMUNITY
- The Coinhibitory Receptor CTLA-4 Controls B Cell Responses by Modulating T Follicular Helper, T Follicular Regulatory, and T Regulatory Cells
- (2014) Peter T. Sage et al. IMMUNITY
- Effects of Low-Dose Recombinant Interleukin 2 to Promote T-Regulatory Cells in Alopecia Areata
- (2014) Emeline Castela et al. JAMA Dermatology
- Attenuation of Donor-Reactive T Cells Allows Effective Control of Allograft Rejection Using Regulatory T Cell Therapy
- (2013) K. Lee et al. AMERICAN JOURNAL OF TRANSPLANTATION
- Costimulation Modulation With Abatacept in Patients With Recent-Onset Type 1 Diabetes: Follow-up 1 Year After Cessation of Treatment
- (2013) Tihamer Orban et al. DIABETES CARE
- A disease-associated PTPN22 variant promotes systemic autoimmunity in murine models
- (2013) Xuezhi Dai et al. JOURNAL OF CLINICAL INVESTIGATION
- Different Modulation of Ptpn22 in Effector and Regulatory T Cells Leads to Attenuation of Autoimmune Diabetes in Transgenic Nonobese Diabetic Mice
- (2013) L.-T. Yeh et al. JOURNAL OF IMMUNOLOGY
- Recent thymic emigrants are the preferential precursors of regulatory T cells differentiated in the periphery
- (2013) R. S. Paiva et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Integrated Enrichment Analysis of Variants and Pathways in Genome-Wide Association Studies Indicates Central Role for IL-2 Signaling Genes in Type 1 Diabetes, and Cytokine Signaling Genes in Crohn's Disease
- (2013) Peter Carbonetto et al. PLoS Genetics
- Targeting of memory T cells with alefacept in new-onset type 1 diabetes (T1DAL study): 12 month results of a randomised, double-blind, placebo-controlled phase 2 trial
- (2013) Mark R Rigby et al. Lancet Diabetes & Endocrinology
- TCR affinity and specificity requirements for human regulatory T-cell function
- (2012) G. Plesa et al. BLOOD
- Following the Fate of One Insulin-Reactive CD4 T cell
- (2012) Georgia Fousteri et al. DIABETES
- Rapamycin/IL-2 Combination Therapy in Patients With Type 1 Diabetes Augments Tregs yet Transiently Impairs -Cell Function
- (2012) S. A. Long et al. DIABETES
- Administration of CD4+CD25highCD127- Regulatory T Cells Preserves -Cell Function in Type 1 Diabetes in Children
- (2012) N. Marek-Trzonkowska et al. DIABETES CARE
- Safety and Efficacy of Antigen-Specific Regulatory T-Cell Therapy for Patients With Refractory Crohn's Disease
- (2012) Pierre Desreumaux et al. GASTROENTEROLOGY
- Pregnancy imprints regulatory memory that sustains anergy to fetal antigen
- (2012) Jared H. Rowe et al. NATURE
- Lack of the Phosphatase PTPN22 Increases Adhesion of Murine Regulatory T Cells to Improve Their Immunosuppressive Function
- (2012) R. J. Brownlie et al. Science Signaling
- The Soluble CTLA-4 Splice Variant Protects From Type 1 Diabetes and Potentiates Regulatory T-Cell Function
- (2011) K. D. Gerold et al. DIABETES
- Insulin as a key autoantigen in the development of type 1 diabetes
- (2011) Maki Nakayama DIABETES-METABOLISM RESEARCH AND REVIEWS
- Register shifting of an insulin peptide–MHC complex allows diabetogenic T cells to escape thymic deletion
- (2011) James F. Mohan et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Plasticity of Human Regulatory T Cells in Healthy Subjects and Patients with Type 1 Diabetes
- (2011) Stephanie A. McClymont et al. JOURNAL OF IMMUNOLOGY
- Co-stimulation modulation with abatacept in patients with recent-onset type 1 diabetes: a randomised, double-blind, placebo-controlled trial
- (2011) Tihamer Orban et al. LANCET
- Peripheral education of the immune system by colonic commensal microbiota
- (2011) Stephanie K. Lathrop et al. NATURE
- A role for interleukin-2 trans-presentation in dendritic cell–mediated T cell activation in humans, as revealed by daclizumab therapy
- (2011) Simone C Wuest et al. NATURE MEDICINE
- Regulatory T-Cell Responses to Low-Dose Interleukin-2 in HCV-Induced Vasculitis
- (2011) David Saadoun et al. NEW ENGLAND JOURNAL OF MEDICINE
- Interleukin-2 and Regulatory T Cells in Graft-versus-Host Disease
- (2011) John Koreth et al. NEW ENGLAND JOURNAL OF MEDICINE
- CD4+CD25+Foxp3+ regulatory T cell formation requires more specific recognition of a self-peptide than thymocyte deletion
- (2011) C. Cozzo Picca et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Trans-Endocytosis of CD80 and CD86: A Molecular Basis for the Cell-Extrinsic Function of CTLA-4
- (2011) O. S. Qureshi et al. SCIENCE
- An autoimmune-associated variant in PTPN2 reveals an impairment of IL-2R signaling in CD4+ T cells
- (2010) S A Long et al. GENES AND IMMUNITY
- TCR ligand density and affinity determine peripheral induction of Foxp3 in vivo
- (2010) Rachel A. Gottschalk et al. JOURNAL OF EXPERIMENTAL MEDICINE
- IL-2 reverses established type 1 diabetes in NOD mice by a local effect on pancreatic regulatory T cells
- (2010) Yenkel Grinberg-Bleyer et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Unique autoreactive T cells recognize insulin peptides generated within the islets of Langerhans in autoimmune diabetes
- (2010) James F Mohan et al. NATURE IMMUNOLOGY
- Diabetogenic T cells recognize insulin bound to IAg7 in an unexpected, weakly binding register
- (2010) B. D. Stadinski et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- EBV-Related Lymphoproliferative Disease Complicating Therapy with the Anti-CD2 Monoclonal Antibody, Siplizumab, in Patients with T-Cell Malignancies
- (2009) D. O'Mahony et al. CLINICAL CANCER RESEARCH
- Defects in IL-2R Signaling Contribute to Diminished Maintenance of FOXP3 Expression in CD4+CD25+ Regulatory T-Cells of Type 1 Diabetic Subjects
- (2009) S. A. Long et al. DIABETES
- Loss of FOXP3 expression in natural human CD4+CD25+regulatory T cells upon repetitivein vitrostimulation
- (2009) Petra Hoffmann et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Genetic association of HLA DQB1 with CD4+CD25+high T-cell apoptosis in type 1 diabetes
- (2009) S Glisic et al. GENES AND IMMUNITY
- Functional Delineation and Differentiation Dynamics of Human CD4+ T Cells Expressing the FoxP3 Transcription Factor
- (2009) Makoto Miyara et al. IMMUNITY
- Genetic Evidence That the Differential Expression of the Ligand-Independent Isoform of CTLA-4 Is the Molecular Basis of the Idd5.1 Type 1 Diabetes Region in Nonobese Diabetic Mice
- (2009) M. Araki et al. JOURNAL OF IMMUNOLOGY
- Cell-specific protein phenotypes for the autoimmune locus IL2RA using a genotype-selectable human bioresource
- (2009) Calliope A Dendrou et al. NATURE GENETICS
- Apoptosis of CD4+CD25high T Cells in Type 1 Diabetes May Be Partially Mediated by IL-2 Deprivation
- (2009) Parthav Jailwala et al. PLoS One
- The Effect of Costimulatory and Interleukin 2 Receptor Blockade on Regulatory T Cells in Renal Transplantation
- (2008) J. A. Bluestone et al. AMERICAN JOURNAL OF TRANSPLANTATION
- Insulin as an autoantigen in NOD/human diabetes
- (2008) Li Zhang et al. CURRENT OPINION IN IMMUNOLOGY
- Expansion of Human Regulatory T-Cells From Patients With Type 1 Diabetes
- (2008) A. L. Putnam et al. DIABETES
- Central Role of Defective Interleukin-2 Production in the Triggering of Islet Autoimmune Destruction
- (2008) Qizhi Tang et al. IMMUNITY
- A Two-Step Process for Thymic Regulatory T Cell Development
- (2008) Chan-Wang Joaquim Lio et al. IMMUNITY
- Meta-analysis of genome-wide association study data identifies additional type 1 diabetes risk loci
- (2008) Jason D Cooper et al. NATURE GENETICS
- The Foxp3+ regulatory T cell: a jack of all trades, master of regulation
- (2008) Qizhi Tang et al. NATURE IMMUNOLOGY
- Concordance for Islet Autoimmunity among Monozygotic Twins
- (2008) Maria J. Redondo et al. NEW ENGLAND JOURNAL OF MEDICINE
- CTLA-4 Control over Foxp3+ Regulatory T Cell Function
- (2008) K. Wing et al. SCIENCE
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now