A disease-associated PTPN22 variant promotes systemic autoimmunity in murine models
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Title
A disease-associated PTPN22 variant promotes systemic autoimmunity in murine models
Authors
Keywords
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Journal
JOURNAL OF CLINICAL INVESTIGATION
Volume 123, Issue 5, Pages 2024-2036
Publisher
American Society for Clinical Investigation
Online
2013-04-23
DOI
10.1172/jci66963
References
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Note: Only part of the references are listed.- PTPN22 Alters the Development of Regulatory T Cells in the Thymus
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- (2012) Torkel Vang et al. Nature Chemical Biology
- Protein tyrosine phosphatases in lymphocyte activation and autoimmunity
- (2012) Inmoo Rhee et al. NATURE IMMUNOLOGY
- Toll-like receptor 7 (TLR7)-driven accumulation of a novel CD11c+ B-cell population is important for the development of autoimmunity
- (2011) A. V. Rubtsov et al. BLOOD
- Substrate Specificity of Lymphoid-specific Tyrosine Phosphatase (Lyp) and Identification of Src Kinase-associated Protein of 55 kDa Homolog (SKAP-HOM) as a Lyp Substrate
- (2011) Xiao Yu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The PTPN22 allele encoding an R620W variant interferes with the removal of developing autoreactive B cells in humans
- (2011) Laurence Menard et al. JOURNAL OF CLINICAL INVESTIGATION
- WASp-deficient B cells play a critical, cell-intrinsic role in triggering autoimmunity
- (2011) Shirly Becker-Herman et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Altered B Cell Homeostasis Is Associated with Type I Diabetes and Carriers of the PTPN22 Allelic Variant
- (2011) T. Habib et al. JOURNAL OF IMMUNOLOGY
- Lyp breakdown and autoimmunity
- (2011) Timothy W Behrens NATURE GENETICS
- The autoimmune disease–associated PTPN22 variant promotes calpain-mediated Lyp/Pep degradation associated with lymphocyte and dendritic cell hyperresponsiveness
- (2011) Jinyi Zhang et al. NATURE GENETICS
- CD45-Csk Phosphatase-Kinase Titration Uncouples Basal and Inducible T Cell Receptor Signaling during Thymic Development
- (2010) Julie Zikherman et al. IMMUNITY
- Phospholipase Cγ1 is essential for T cell development, activation, and tolerance
- (2010) Guoping Fu et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Molecular orchestration of differentiation and function of regulatory T cells
- (2009) L.-F. Lu et al. GENES & DEVELOPMENT
- Transitional B Cells Exhibit a B Cell Receptor-Specific Nuclear Defect in Gene Transcription
- (2009) S. F. Andrews et al. JOURNAL OF IMMUNOLOGY
- PTPN22 Deficiency Cooperates with the CD45 E613R Allele to Break Tolerance on a Non-Autoimmune Background
- (2009) J. Zikherman et al. JOURNAL OF IMMUNOLOGY
- Cutting Edge: The PTPN22 Allelic Variant Associated with Autoimmunity Impairs B Cell Signaling
- (2009) A. F. Arechiga et al. JOURNAL OF IMMUNOLOGY
- Protein Tyrosine Phosphatases in Autoimmunity
- (2008) Torkel Vang et al. Annual Review of Immunology
- Characterization of a late transitional B cell population highly sensitive to BAFF-mediated homeostatic proliferation
- (2008) Almut Meyer-Bahlburg et al. JOURNAL OF EXPERIMENTAL MEDICINE
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