Pharmacogenetics of Lipid-Lowering Agents: Precision or Indecision Medicine?
Published 2016 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Pharmacogenetics of Lipid-Lowering Agents: Precision or Indecision Medicine?
Authors
Keywords
Pharmacogenetics, Hypolipidemic agents, Hydroxymethylglutaryl-CoA reductase inhibitors, Dyslipidemias
Journal
Current Atherosclerosis Reports
Volume 18, Issue 5, Pages -
Publisher
Springer Nature
Online
2016-03-19
DOI
10.1007/s11883-016-0573-6
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Role of rs3846662 and HMGCR alternative splicing in statin efficacy and baseline lipid levels in familial hypercholesterolemia
- (2016) Valerie Leduc et al. Pharmacogenetics and Genomics
- Nonstatin Low-Density Lipoprotein–Lowering Therapy and Cardiovascular Risk Reduction—Statement FromATVBCouncil: Table.
- (2015) Robert A. Hegele et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Targeted next-generation sequencing in monogenic dyslipidemias
- (2015) Robert A. Hegele et al. CURRENT OPINION IN LIPIDOLOGY
- APOE Polymorphisms Contribute to Reduced Atorvastatin Response in Chilean Amerindian Subjects
- (2015) Jenny Lagos et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Differential Lipid Response to Statins Is Associated With Variants in the BUD13–APOA5 Gene Region
- (2015) Sarah E. OʼBrien et al. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY
- Effect of Naturally Random Allocation to Lower Low-Density Lipoprotein Cholesterol on the Risk of Coronary Heart Disease Mediated by Polymorphisms in NPC1L1, HMGCR, or Both
- (2015) Brian A. Ference et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials
- (2015) Daniel I Swerdlow et al. LANCET
- Inhibition of PCSK9 with evolocumab in homozygous familial hypercholesterolaemia (TESLA Part B): a randomised, double-blind, placebo-controlled trial
- (2015) Frederick J Raal et al. LANCET
- PCSK9 inhibition with evolocumab (AMG 145) in heterozygous familial hypercholesterolaemia (RUTHERFORD-2): a randomised, double-blind, placebo-controlled trial
- (2015) Frederick J Raal et al. LANCET
- Association Between SLCO1B1 Gene T521C Polymorphism and Statin-Related Myopathy Risk
- (2015) Qingtao Hou et al. MEDICINE
- Statin Lactonization by Uridine 5′-Diphospho-glucuronosyltransferases (UGTs)
- (2015) Tom J. J. Schirris et al. MOLECULAR PHARMACEUTICS
- Chylomicronaemia—current diagnosis and future therapies
- (2015) Amanda J. Brahm et al. Nature Reviews Endocrinology
- Antisense Inhibition of Apolipoprotein C-III in Patients with Hypertriglyceridemia
- (2015) Daniel Gaudet et al. NEW ENGLAND JOURNAL OF MEDICINE
- The rs13064411 polymorphism in the WDR52 gene, associated with PCSK9 levels, modifies statin-induced changes in serum total and LDL cholesterol levels
- (2015) Catherine E. de Keyser et al. Pharmacogenetics and Genomics
- Possible association of ABCB1:c.3435T>C polymorphism with high-density-lipoprotein-cholesterol response to statin treatment - a pilot study.
- (2015) Anna Sałacka et al. Bosnian Journal of Basic Medical Sciences
- Rare LPL gene variants attenuate triglyceride reduction and HDL cholesterol increase in response to fenofibric acid therapy in individuals with mixed dyslipidemia
- (2014) Feng Gao et al. ATHEROSCLEROSIS
- Pharmacogenomics, Lipid Disorders, and Treatment Options
- (2014) S E Gryn et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Targeting APOC3 in the Familial Chylomicronemia Syndrome
- (2014) Daniel Gaudet et al. NEW ENGLAND JOURNAL OF MEDICINE
- Pharmacogenetic meta-analysis of genome-wide association studies of LDL cholesterol response to statins
- (2014) Iris Postmus et al. Nature Communications
- Narrative Review: Statin-Related Myopathy
- (2013) Tisha R. Joy ANNALS OF INTERNAL MEDICINE
- Diagnosis, Prevention, and Management of Statin Adverse Effects and Intolerance: Canadian Working Group Consensus Update
- (2013) G.B. John Mancini et al. CANADIAN JOURNAL OF CARDIOLOGY
- Clinical and Pharmacogenetic Predictors of Circulating Atorvastatin and Rosuvastatin Concentrations in Routine Clinical Care
- (2013) Marianne K. DeGorter et al. Circulation-Cardiovascular Genetics
- Cholesteryl Ester Transfer Protein Polymorphisms, Statin Use, and Their Impact on Cholesterol Levels and Cardiovascular Events
- (2013) M Leusink et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Evaluation of the pharmacokinetics and drug interactions of the two recently developed statins, rosuvastatin and pitavastatin
- (2013) Miao Hu et al. Expert Opinion on Drug Metabolism & Toxicology
- RareAPOA5promoter variants associated with paradoxical HDL cholesterol decrease in response to fenofibric acid therapy
- (2013) Ariel Brautbar et al. JOURNAL OF LIPID RESEARCH
- A statin-dependent QTL for GATM expression is associated with statin-induced myopathy
- (2013) Lara M. Mangravite et al. NATURE
- Pharmacogenomics of lipid-lowering therapies
- (2013) Miao Hu et al. PHARMACOGENOMICS
- Severe Hypertriglyceridemia With Pancreatitis
- (2013) Frank M. Sacks et al. JAMA Internal Medicine
- Genetic Determinants of Statin-Induced Low-Density Lipoprotein Cholesterol Reduction
- (2012) Daniel I. Chasman et al. Circulation-Cardiovascular Genetics
- The Clinical Pharmacogenomics Implementation Consortium: CPIC Guideline for SLCO1B1 and Simvastatin-Induced Myopathy
- (2012) R A Wilke et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Lipoprotein(a)
- (2012) Joseph B. Dubé et al. CURRENT OPINION IN LIPIDOLOGY
- Impact of common genetic variation on response to simvastatin therapy among 18 705 participants in the Heart Protection Study
- (2012) Jemma C. Hopewell et al. EUROPEAN HEART JOURNAL
- Genome-wide association study of genetic determinants of LDL-c response to atorvastatin therapy: importance of Lp(a)
- (2012) Harshal A. Deshmukh et al. JOURNAL OF LIPID RESEARCH
- Efficacy and safety of a microsomal triglyceride transfer protein inhibitor in patients with homozygous familial hypercholesterolaemia: a single-arm, open-label, phase 3 study
- (2012) Marina Cuchel et al. LANCET
- The PPAR alpha gene is associated with triglyceride, low-density cholesterol and inflammation marker response to fenofibrate intervention: the GOLDN study
- (2012) A C Frazier-Wood et al. PHARMACOGENOMICS JOURNAL
- Genome-Wide Study of Gene Variants Associated with Differential Cardiovascular Event Reduction by Pravastatin Therapy
- (2012) Dov Shiffman et al. PLoS One
- Variants Identified in a GWAS Meta-Analysis for Blood Lipids Are Associated with the Lipid Response to Fenofibrate
- (2012) Stella Aslibekyan et al. PLoS One
- Meta-Analyses of KIF6 Trp719Arg in Coronary Heart Disease and Statin Therapeutic Effect
- (2012) Ping Peng et al. PLoS One
- Mechanisms of statin-induced myalgia assessed by physiogenomic associations
- (2011) Gualberto Ruaño et al. ATHEROSCLEROSIS
- Genetic variation at the SLCO1B1 gene locus and low density lipoprotein cholesterol lowering response to pravastatin in the elderly
- (2011) Hironobu Akao et al. ATHEROSCLEROSIS
- Sortilin: An unusual suspect in cholesterol metabolism
- (2011) Joseph B. Dubé et al. BIOESSAYS
- Genetic variation in the ABCC2 gene is associated with dose decreases or switches to other cholesterol-lowering drugs during simvastatin and atorvastatin therapy
- (2011) M L Becker et al. PHARMACOGENOMICS JOURNAL
- Organic Anion Transporting Polypeptide 1B1: a Genetically Polymorphic Transporter of Major Importance for Hepatic Drug Uptake
- (2011) M. Niemi et al. PHARMACOLOGICAL REVIEWS
- ABCG2 Polymorphism Is Associated With the Low-Density Lipoprotein Cholesterol Response to Rosuvastatin
- (2010) B Tomlinson et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Mipomersen, an apolipoprotein B synthesis inhibitor, for lowering of LDL cholesterol concentrations in patients with homozygous familial hypercholesterolaemia: a randomised, double-blind, placebo-controlled trial
- (2010) Frederick J Raal et al. LANCET
- Biological, clinical and population relevance of 95 loci for blood lipids
- (2010) Tanya M. Teslovich et al. NATURE
- Genome-Wide Association of Lipid-Lowering Response to Statins in Combined Study Populations
- (2010) Mathew J. Barber et al. PLoS One
- Identification of Genetic Variants Associated With Response to Statin Therapy
- (2009) Jessica L. Mega et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Comprehensive Whole-Genome and Candidate Gene Analysis for Response to Statin Therapy in the Treating to New Targets (TNT) Cohort
- (2009) John F. Thompson et al. Circulation-Cardiovascular Genetics
- UDP-Glucuronosyltransferase (UGT) Polymorphisms Affect Atorvastatin Lactonization In Vitro and In Vivo
- (2009) S Riedmaier et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Plasma lipoproteins: genetic influences and clinical implications
- (2009) Robert A. Hegele NATURE REVIEWS GENETICS
- Intramuscular Administration of AAV1-Lipoprotein Lipase S447X Lowers Triglycerides in Lipoprotein Lipase–Deficient Patients
- (2008) Erik S. Stroes et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Genetic variation at the LDL receptor and HMG-CoA reductase gene loci, lipid levels, statin response, and cardiovascular disease incidence in PROSPER
- (2008) Eliana Polisecki et al. ATHEROSCLEROSIS
- Variation in the 3-Hydroxyl-3-Methylglutaryl Coenzyme A Reductase Gene Is Associated With Racial Differences in Low-Density Lipoprotein Cholesterol Response to Simvastatin Treatment
- (2008) Ronald M. Krauss et al. CIRCULATION
- CETP genotype predicts increased mortality in statin-treated men with proven cardiovascular disease: an adverse pharmacogenetic interaction
- (2008) J. J. Regieli et al. EUROPEAN HEART JOURNAL
- Association of Cholesteryl Ester Transfer Protein Genotypes With CETP Mass and Activity, Lipid Levels, and Coronary Risk
- (2008) Alexander Thompson JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Association of the Trp719Arg Polymorphism in Kinesin-Like Protein 6 With Myocardial Infarction and Coronary Heart Disease in 2 Prospective Trials
- (2008) Olga A. Iakoubova et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- SLCO1B1Variants and Statin-Induced Myopathy — A Genomewide Study
- (2008) NEW ENGLAND JOURNAL OF MEDICINE
- Association between a frequent allele of the gene encoding OATP1B1 and enhanced LDL-lowering response to fluvastatin therapy
- (2008) Philippe Couvert et al. PHARMACOGENOMICS
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started