Exploration of Biomarkers for Amoxicillin/Clavulanate-Induced Liver Injury: Multi-Omics Approaches

Characterization of amoxicillin- and clavulanic acid-specific T cells in patients with amoxicillin-clavulanate-induced liver injury

(2015) Seung-Hyun Kim et al.   HEPATOLOGY

Drug-Induced Liver Injury: Morbidity, Mortality, and Hy’s Law

(2014) Arie Regev et al.   GASTROENTEROLOGY

The association betweenHLA-DQB1polymorphism and antituberculosis drug-induced liver injury: a Case-Control Study

(2014) R. Chen et al.   JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS

Detection of hepatotoxicity potential with metabolite profiling (metabolomics) of rat plasma

(2014) W. Mattes et al.   TOXICOLOGY LETTERS

MicroRNAs as potential circulating biomarkers of drug-induced liver injury: key current and future issues for translation to humans

(2014) Robert James Hornby et al.   Expert Review of Clinical Pharmacology

Liver-specific microRNAs as biomarkers of nanomaterial-induced liver damage

(2013) Takashi Nagano et al.   NANOTECHNOLOGY

HLA Alleles Influence the Clinical Signature of Amoxicillin-Clavulanate Hepatotoxicity

(2013) Camilla Stephens et al.   PLoS One

Metabolomics Identifies an Inflammatory Cascade Involved in Dioxin- and Diet-Induced Steatohepatitis

(2012) Tsutomu Matsubara et al.   Cell Metabolism

Serum microRNA Biomarkers for Drug-Induced Liver Injury

(2012) P J Starkey Lewis et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Circulating microRNAs in exosomes indicate hepatocyte injury and inflammation in alcoholic, drug-induced, and inflammatory liver diseases

(2012) Shashi Bala et al.   HEPATOLOGY

Susceptibility to Amoxicillin-Clavulanate-Induced Liver Injury Is Influenced by Multiple HLA Class I and II Alleles

(2011) M. Isabel Lucena et al.   GASTROENTEROLOGY

Circulating microRNAs as potential markers of human drug-induced liver injury

(2011) Philip J. Starkey Lewis et al.   HEPATOLOGY

MicroRNAs are transported in plasma and delivered to recipient cells by high-density lipoproteins

(2011) Kasey C. Vickers et al.   NATURE CELL BIOLOGY

Mechanisms of drug-induced liver injury: from bedside to bench

(2011) Shannan Tujios et al.   Nature Reviews Gastroenterology & Hepatology

Market withdrawal of new molecular entities approved in the United States from 1980 to 2009

(2011) Zaina P. Qureshi et al.   PHARMACOEPIDEMIOLOGY AND DRUG SAFETY

Argonaute2 complexes carry a population of circulating microRNAs independent of vesicles in human plasma

(2011) J. D. Arroyo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Application of Metabonomics to Predict Drug-Induced Liver Injury

(2010) T M O'Connell et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Use of Pharmaco-Metabonomics for Early Prediction of Acetaminophen-Induced Hepatotoxicity in Humans

(2010) J H Winnike et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Azelaic acid modulates the inflammatory response in normal human keratinocytes through PPARγ activation

(2010) Arianna Mastrofrancesco et al.   EXPERIMENTAL DERMATOLOGY

Drug-induced liver injury: Is it time for genetics to change our clinical practice?

(2010) Pietro Invernizzi   JOURNAL OF HEPATOLOGY

Alanine aminotransferase: Is it healthy to be “normal”?

(2009) D. Robert Dufour   HEPATOLOGY

Estimation of the healthy upper limits for serum alanine aminotransferase in Asian populations with normal liver histology

(2009) Jae Keun Lee et al.   HEPATOLOGY

HLA-B*5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin

(2009) Ann K Daly et al.   NATURE GENETICS

Pharmacometabonomic identification of a significant host-microbiome metabolic interaction affecting human drug metabolism

(2009) T. A. Clayton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fast-food-based hyper-alimentation can induce rapid and profound elevation of serum alanine aminotransferase in healthy subjects

(2008) S. Kechagias et al.   GUT

GlutathioneS-transferase m1 and t1 null genotypes increase susceptibility to idiosyncratic drug-induced liver injury

(2008) M. Isabel Lucena et al.   HEPATOLOGY

Independent associations of alanine aminotransferase (ALT) levels with cardiovascular risk factor clustering in Chinese adolescents

(2008) Alice P.S. Kong et al.   JOURNAL OF HEPATOLOGY

Detection of microRNA Expression in Human Peripheral Blood Microvesicles

(2008) Melissa Piper Hunter et al.   PLoS One