Agrin induces long-term osteochondral regeneration by supporting repair morphogenesis
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Title
Agrin induces long-term osteochondral regeneration by supporting repair morphogenesis
Authors
Keywords
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Journal
Science Translational Medicine
Volume 12, Issue 559, Pages eaax9086
Publisher
American Association for the Advancement of Science (AAAS)
Online
2020-09-03
DOI
10.1126/scitranslmed.aax9086
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Note: Only part of the references are listed.- Modulation of the Wnt pathway through inhibition of CLK2 and DYRK1A by lorecivivint as a novel, potentially disease-modifying approach for knee osteoarthritis treatment
- (2019) V. Deshmukh et al. OSTEOARTHRITIS AND CARTILAGE
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- (2018) V. Deshmukh et al. OSTEOARTHRITIS AND CARTILAGE
- A novel Wnt pathway inhibitor, SM04690, for the treatment of moderate to severe osteoarthritis of the knee: results of a 24-week, randomized, controlled, phase 1 study
- (2017) Y. Yazici et al. OSTEOARTHRITIS AND CARTILAGE
- Articular cartilage and joint development from embryogenesis to adulthood
- (2017) Rebekah S. Decker SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Joint morphogenetic cells in the adult mammalian synovium
- (2017) Anke J. Roelofs et al. Nature Communications
- DOT1L safeguards cartilage homeostasis and protects against osteoarthritis
- (2017) Silvia Monteagudo et al. Nature Communications
- WNT16 antagonises excessive canonical WNT activation and protects cartilage in osteoarthritis
- (2016) Giovanna Nalesso et al. ANNALS OF THE RHEUMATIC DISEASES
- The cyclic AMP signaling pathway: Exploring targets for successful drug discovery (Review)
- (2016) KUO YAN et al. Molecular Medicine Reports
- Joint Development Involves a Continuous Influx of Gdf5-Positive Cells
- (2016) Yulia Shwartz et al. Cell Reports
- The cAMP Pathway as Therapeutic Target in Autoimmune and Inflammatory Diseases
- (2016) Verena Katharina Raker et al. Frontiers in Immunology
- Identification of Targets of a New Nutritional Mixture for Osteoarthritis Management Composed by Curcuminoids Extract, Hydrolyzed Collagen and Green Tea Extract
- (2016) Fanny Comblain et al. PLoS One
- Agrin mediates chondrocyte homeostasis and requires both LRP4 and α-dystroglycan to enhance cartilage formation in vitro and in vivo
- (2015) Suzanne Eldridge et al. ANNALS OF THE RHEUMATIC DISEASES
- Identification of a Potent Inhibitor of CREB-Mediated Gene Transcription with Efficacious in Vivo Anticancer Activity
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- (2014) E N Blaney Davidson et al. ANNALS OF THE RHEUMATIC DISEASES
- LRP4 induces extracellular matrix productions and facilitates chondrocyte differentiation
- (2014) Nobuyuki Asai et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Health economics in the field of osteoarthritis: An Expert's consensus paper from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO)
- (2013) Mickaël Hiligsmann et al. SEMINARS IN ARTHRITIS AND RHEUMATISM
- NIH Image to ImageJ: 25 years of image analysis
- (2012) Caroline A Schneider et al. NATURE METHODS
- Wnt Proteins
- (2012) K. Willert et al. Cold Spring Harbor Perspectives in Biology
- Alternative Wnt Pathways and Receptors
- (2012) R. van Amerongen Cold Spring Harbor Perspectives in Biology
- Small molecule-based disruption of the Axin/β-catenin protein complex regulates mesenchymal stem cell differentiation
- (2011) Jungsug Gwak et al. CELL RESEARCH
- WNT-3A modulates articular chondrocyte phenotype by activating both canonical and noncanonical pathways
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- Roles of β-catenin signaling in phenotypic expression and proliferation of articular cartilage superficial zone cells
- (2011) Rika Yasuhara et al. LABORATORY INVESTIGATION
- CREB and the CRTC co-activators: sensors for hormonal and metabolic signals
- (2011) Judith Y. Altarejos et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Bone Morphogenetic Proteins and articular cartilage
- (2010) P.M. van der Kraan et al. OSTEOARTHRITIS AND CARTILAGE
- Analyses of early events during chondrogenic repair in rat full-thickness articular cartilage defects
- (2009) Yoshihisa Anraku et al. JOURNAL OF BONE AND MINERAL METABOLISM
- Lrp4, a Novel Receptor for Dickkopf 1 and Sclerostin, Is Expressed by Osteoblasts and Regulates Bone Growth and Turnover In Vivo
- (2009) Hong Y. Choi et al. PLoS One
- Identification of the molecular response of articular cartilage to injury, by microarray screening: Wnt-16 expression and signaling after injury and in osteoarthritis
- (2008) Francesco Dell'Accio et al. ARTHRITIS AND RHEUMATISM
- A distinct cohort of progenitor cells participates in synovial joint and articular cartilage formation during mouse limb skeletogenesis
- (2008) Eiki Koyama et al. DEVELOPMENTAL BIOLOGY
- LRP4 Serves as a Coreceptor of Agrin
- (2008) Bin Zhang et al. NEURON
- Nicotine-induced phosphorylation of phosphorylated cyclic AMP response element-binding protein (pCREB) in hippocampal neurons is potentiated by agrin
- (2008) Christian Chiamulera et al. NEUROSCIENCE LETTERS
- A novel in vivo murine model of cartilage regeneration. Age and strain-dependent outcome after joint surface injury
- (2008) N.M. Eltawil et al. OSTEOARTHRITIS AND CARTILAGE
- Wnt–β-catenin signaling in the pathogenesis of osteoarthritis
- (2008) Maripat Corr Nature clinical practice. Rheumatology
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