Endothelial extracellular vesicles contain protective proteins and rescue ischemia-reperfusion injury in a human heart-on-chip

Multitarget Strategies to Reduce Myocardial Ischemia/Reperfusion Injury

(2019) Sean M. Davidson et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Exosome-mimetic nanovesicles contain distinct proteome and post-translational modified protein cargo, in comparison to exosomes

(2019) Amirmohammad Nasiri Kenari et al.   PROTEOMICS

Reassessment of Exosome Composition

(2019) Dennis K. Jeppesen et al.   CELL

Proteasome 19S RP and translation preinitiation complexes are secreted within exosomes upon serum starvation

(2019) Nicole Bec et al.   TRAFFIC

Characterization of Protein Profiling and mRNA Expression of LLC Exosomes

(2019) Wen Zhang et al.   PROTEIN JOURNAL

Exosomal microRNA-21-5p Mediates Mesenchymal Stem Cell Paracrine Effects on Human Cardiac Tissue ContractilityNovelty and Significance

(2018) Joshua Mayourian et al.   CIRCULATION RESEARCH

Clinical Studies of Cell Therapy in Cardiovascular Medicine

(2018) Monisha N. Banerjee et al.   CIRCULATION RESEARCH

Endothelial cells release cardioprotective exosomes that may contribute to ischaemic preconditioning

(2018) Sean M. Davidson et al.   Scientific Reports

Toward improved myocardial maturity in an organ-on-chip platform with immature cardiac myocytes

(2017) Sean P Sheehy et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Cardiac microphysiological devices with flexible thin-film sensors for higher-throughput drug screening

(2017) Johan U. Lind et al.   LAB ON A CHIP

Exploring the RNA landscape of endothelial exosomes

(2017) Jennifer Pérez-Boza et al.   RNA

Time to Give Up on Cardioprotection?

(2016) Gerd Heusch et al.   CIRCULATION RESEARCH

PreSERVE-AMINovelty and Significance

(2016) Arshed A. Quyyumi et al.   CIRCULATION RESEARCH

Exosomes derived from endothelial progenitor cells attenuate vascular repair and accelerate reendothelialization by enhancing endothelial function

(2016) Xiaocong Li et al.   CYTOTHERAPY

Revascularization in Patients With Severe Left Ventricular Dysfunction

(2016) Nandan S. Anavekar et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Instrumented cardiac microphysiological devices via multimaterial three-dimensional printing

(2016) Johan U. Lind et al.   NATURE MATERIALS

Bone Marrow Mesenchymal Stem Cells (BM-MSCs) Improve Heart Function in Swine Myocardial Infarction Model through Paracrine Effects

(2016) Min Cai et al.   Scientific Reports

Cell-specific uptake of mantle cell lymphoma-derived exosomes by malignant and non-malignant B-lymphocytes

(2015) Inbal Hazan-Halevy et al.   CANCER LETTERS

Mesenchymal Stem Cell-Derived Exosomes Improve the Microenvironment of Infarcted Myocardium Contributing to Angiogenesis and Anti-Inflammation

(2015) Xiaomei Teng et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Heart Disease and Stroke Statistics—2016 Update

(2015) Dariush Mozaffarian et al.   CIRCULATION

Embryonic Stem Cell-Derived Exosomes Promote Endogenous Repair Mechanisms and Enhance Cardiac Function Following Myocardial Infarction

(2015) M. Khan et al.   CIRCULATION RESEARCH

Proteomic signatures of extracellular vesicles secreted by nonmineralizing and mineralizing human osteoblasts and stimulation of tumor cell growth

(2015) Jess Morhayim et al.   FASEB JOURNAL

Plasma Exosomes Protect the Myocardium From Ischemia-Reperfusion Injury

(2015) Jose M. Vicencio et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Potential extra-ribosomal functions of ribosomal proteins in Saccharomyces cerevisiae

(2015) Hui Lu et al.   MICROBIOLOGICAL RESEARCH

Extracellular vesicles from human cardiac progenitor cells inhibit cardiomyocyte apoptosis and improve cardiac function after myocardial infarction

(2014) L. Barile et al.   CARDIOVASCULAR RESEARCH

Modeling the mitochondrial cardiomyopathy of Barth syndrome with induced pluripotent stem cell and heart-on-chip technologies

(2014) Gang Wang et al.   NATURE MEDICINE

STRING v10: protein–protein interaction networks, integrated over the tree of life

(2014) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

Visual account of protein investment in cellular functions

(2014) W. Liebermeister et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Exosomes as Critical Agents of Cardiac Regeneration Triggered by Cell Therapy

(2014) Ahmed Gamal-Eldin Ibrahim et al.   Stem Cell Reports

Animal models of human disease: Challenges in enabling translation

(2013) Paul McGonigle et al.   BIOCHEMICAL PHARMACOLOGY

Translating cardioprotection for patient benefit: position paper from the Working Group of Cellular Biology of the Heart of the European Society of Cardiology

(2013) Derek J. Hausenloy et al.   CARDIOVASCULAR RESEARCH

Bone-Derived Stem Cells Repair the Heart After Myocardial Infarction Through Transdifferentiation and Paracrine Signaling Mechanisms

(2013) Jason M. Duran et al.   CIRCULATION RESEARCH

Exosome Uptake Depends on ERK1/2-Heat Shock Protein 27 Signaling and Lipid Raft-mediated Endocytosis Negatively Regulated by Caveolin-1

(2013) Katrin J. Svensson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Myocardial ischemia-reperfusion injury: a neglected therapeutic target

(2013) Derek J. Hausenloy et al.   JOURNAL OF CLINICAL INVESTIGATION

Large-scale gene function analysis with the PANTHER classification system

(2013) Huaiyu Mi et al.   Nature Protocols

Hypoxia-Induced Changes in the Bioactivity of Cytotrophoblast-Derived Exosomes

(2013) Carlos Salomon et al.   PLoS One

Hypoxic enhancement of exosome release by breast cancer cells

(2012) Hamish W King et al.   BMC CANCER

Identification of potential target genes of cardioprotection against ischemia–reperfusion injury by express sequence tags analysis in rat hearts

(2012) Hyoung Kyu Kim et al.   Journal of Cardiology

Mechanism of transfer of functional microRNAs between mouse dendritic cells via exosomes

(2011) A. Montecalvo et al.   BLOOD

Assessing bioenergetic function in response to oxidative stress by metabolic profiling

(2011) Brian P. Dranka et al.   FREE RADICAL BIOLOGY AND MEDICINE

Selective transfer of exosomes from oligodendrocytes to microglia by macropinocytosis

(2011) D. Fitzner et al.   JOURNAL OF CELL SCIENCE

Bioenergetic function in cardiovascular cells: The importance of the reserve capacity and its biological regulation

(2010) Brian E. Sansbury et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Lipid raft-dependent endocytosis: a new route for hepcidin-mediated regulation of ferroportin in macrophages

(2010) A. Auriac et al.   HAEMATOLOGICA

Exosome secreted by MSC reduces myocardial ischemia/reperfusion injury

(2010) Ruenn Chai Lai et al.   Stem Cell Research

Roles for Endoplasmic Reticulum–Associated Degradation and the Novel Endoplasmic Reticulum Stress Response Gene Derlin-3 in the Ischemic Heart

(2009) Peter J. Belmont et al.   CIRCULATION RESEARCH

Mitochondrial Permeability Transition Pore Opening as a Promising Therapeutic Target in Cardiac Diseases

(2009) S. Javadov et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Universal sample preparation method for proteome analysis

(2009) Jacek R Wiśniewski et al.   NATURE METHODS

Protein denitrosylation: enzymatic mechanisms and cellular functions

(2009) Moran Benhar et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Non-parametric estimation of posterior error probabilities associated with peptides identified by tandem mass spectrometry

(2008) L. Kall et al.   BIOINFORMATICS

Ischemia-induced ribosomal protein S3 expressional changes and the neuroprotective effect against experimental cerebral ischemic damage

(2008) In Koo Hwang et al.   JOURNAL OF NEUROSCIENCE RESEARCH