Journal
MICROBIOLOGICAL RESEARCH
Volume 177, Issue -, Pages 28-33Publisher
ELSEVIER GMBH, URBAN & FISCHER VERLAG
DOI: 10.1016/j.micres.2015.05.004
Keywords
Extra-ribosomal function; Ribosomal protein; Saccharomyces cerevisiae
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Funding
- National Natural Science Foundation of China [81401552]
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Ribosomal proteins (RPs), are essential components of the ribosomes, the molecular machines that turn mRNA blueprints into proteins, as they serve to stabilize the structure of the rRNA, thus improving protein biosynthesis. In addition, growing evidence suggests that RPs can function in other cellular roles. In the present review, we summarize several potential extra-ribosomal functions of RPs in ribosomal biogenesis, transcription activity, translation process, DNA repair, replicative life span, adhesive growth, and morphological transformation in Saccharomyces cerevisiae. However, the future in-depth studies are needed to identify these novel secondary functions of RPs in S. cerevisiae. (C) 2015 Elsevier GmbH. All rights reserved.
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